171 related articles for article (PubMed ID: 24564229)
1. Folate-vinca alkaloid conjugates for cancer therapy: a structure-activity relationship.
Leamon CP; Vlahov IR; Reddy JA; Vetzel M; Santhapuram HK; You F; Bloomfield A; Dorton R; Nelson M; Kleindl P; Vaughn JF; Westrick E
Bioconjug Chem; 2014 Mar; 25(3):560-8. PubMed ID: 24564229
[TBL] [Abstract][Full Text] [Related]
2. Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
Leamon CP; Reddy JA; Vlahov IR; Westrick E; Parker N; Nicoson JS; Vetzel M
Int J Cancer; 2007 Oct; 121(7):1585-92. PubMed ID: 17551919
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of EC140: a novel folate-targeted vinca alkaloid conjugate.
Leamon CP; Reddy JA; Vlahov IR; Kleindl PJ; Vetzel M; Westrick E
Bioconjug Chem; 2006; 17(5):1226-32. PubMed ID: 16984132
[TBL] [Abstract][Full Text] [Related]
4. Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate.
Reddy JA; Dorton R; Westrick E; Dawson A; Smith T; Xu LC; Vetzel M; Kleindl P; Vlahov IR; Leamon CP
Cancer Res; 2007 May; 67(9):4434-42. PubMed ID: 17483358
[TBL] [Abstract][Full Text] [Related]
5. EC-145, a folate-targeted Vinca alkaloid conjugate for the potential treatment of folate receptor-expressing cancers.
Dosio F; Milla P; Cattel L
Curr Opin Investig Drugs; 2010 Dec; 11(12):1424-33. PubMed ID: 21154124
[TBL] [Abstract][Full Text] [Related]
6. Preclinical antitumor activity of a novel folate-targeted dual drug conjugate.
Leamon CP; Reddy JA; Vlahov IR; Westrick E; Dawson A; Dorton R; Vetzel M; Santhapuram HK; Wang Y
Mol Pharm; 2007; 4(5):659-67. PubMed ID: 17874843
[TBL] [Abstract][Full Text] [Related]
7. Regioselective synthesis of folate receptor-targeted agents derived from epothilone analogs and folic acid.
Vlahov IR; Vite GD; Kleindl PJ; Wang Y; Santhapuram HK; You F; Howard SJ; Kim SH; Lee FF; Leamon CP
Bioorg Med Chem Lett; 2010 Aug; 20(15):4578-81. PubMed ID: 20594844
[TBL] [Abstract][Full Text] [Related]
8. Positive interaction of bisbenzylisoquinoline alkaloid, cepharanthin, with vinca alkaloid agents against human tumors.
Ono M; Tanaka N
In Vivo; 1997; 11(3):233-41. PubMed ID: 9239517
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and structure-activity relationship studies of cytotoxic vinorelbine amide analogues.
Hu L; Song W; Meng Y; Guo D; Liu X; Hu L
Bioorg Med Chem Lett; 2012 Dec; 22(24):7547-50. PubMed ID: 23107481
[TBL] [Abstract][Full Text] [Related]
10. Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate.
Reddy JA; Westrick E; Santhapuram HK; Howard SJ; Miller ML; Vetzel M; Vlahov I; Chari RV; Goldmacher VS; Leamon CP
Cancer Res; 2007 Jul; 67(13):6376-82. PubMed ID: 17616697
[TBL] [Abstract][Full Text] [Related]
11. In vivo structural activity and optimization studies of folate-tubulysin conjugates.
Reddy JA; Dorton R; Dawson A; Vetzel M; Parker N; Nicoson JS; Westrick E; Klein PJ; Wang Y; Vlahov IR; Leamon CP
Mol Pharm; 2009; 6(5):1518-25. PubMed ID: 19630399
[TBL] [Abstract][Full Text] [Related]
12. Folate receptor specific anti-tumor activity of folate-mitomycin conjugates.
Reddy JA; Westrick E; Vlahov I; Howard SJ; Santhapuram HK; Leamon CP
Cancer Chemother Pharmacol; 2006 Aug; 58(2):229-36. PubMed ID: 16331500
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and biological evaluation of a highly-potent and cancer cell selective folate-taxoid conjugate.
Seitz JD; Vineberg JG; Herlihy E; Park B; Melief E; Ojima I
Bioorg Med Chem; 2015 May; 23(9):2187-94. PubMed ID: 25819334
[TBL] [Abstract][Full Text] [Related]
14. Vinflunine, the latest Vinca alkaloid in clinical development. A review of its preclinical anticancer properties.
Kruczynski A; Hill BT
Crit Rev Oncol Hematol; 2001 Nov; 40(2):159-73. PubMed ID: 11682323
[TBL] [Abstract][Full Text] [Related]
15. Comparative evaluation of the biological properties of reducible and acid-sensitive folate prodrugs of a highly potent doxorubicin derivative.
Abu Ajaj K; El-Abadla N; Welker P; Azab S; Zeisig R; Fichtner I; Kratz F
Eur J Cancer; 2012 Sep; 48(13):2054-65. PubMed ID: 21937219
[TBL] [Abstract][Full Text] [Related]
16. Preclinical in vivo antitumor activity of vinflunine, a novel fluorinated Vinca alkaloid.
Kruczynski A; Colpaert F; Tarayre JP; Mouillard P; Fahy J; Hill BT
Cancer Chemother Pharmacol; 1998; 41(6):437-47. PubMed ID: 9554586
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and SAR of vinca alkaloid analogues.
Voss ME; Ralph JM; Xie D; Manning DD; Chen X; Frank AJ; Leyhane AJ; Liu L; Stevens JM; Budde C; Surman MD; Friedrich T; Peace D; Scott IL; Wolf M; Johnson R
Bioorg Med Chem Lett; 2009 Feb; 19(4):1245-9. PubMed ID: 19147348
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of a folate-targeted rhaponticin conjugate.
Liang X; Sun Y; Zeng W; Liu L; Ma X; Zhao Y; Fan J
Bioorg Med Chem; 2013 Jan; 21(1):178-85. PubMed ID: 23177726
[TBL] [Abstract][Full Text] [Related]
19. Phase I study of folate conjugate EC145 (Vintafolide) in patients with refractory solid tumors.
Lorusso PM; Edelman MJ; Bever SL; Forman KM; Pilat M; Quinn MF; Li J; Heath EI; Malburg LM; Klein PJ; Leamon CP; Messmann RA; Sausville EA
J Clin Oncol; 2012 Nov; 30(32):4011-6. PubMed ID: 23032618
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and activity of a folate peptide camptothecin prodrug.
Henne WA; Doorneweerd DD; Hilgenbrink AR; Kularatne SA; Low PS
Bioorg Med Chem Lett; 2006 Oct; 16(20):5350-5. PubMed ID: 16901694
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]