These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Jang KJ; Mehr AP; Hamilton GA; McPartlin LA; Chung S; Suh KY; Ingber DE Integr Biol (Camb); 2013 Sep; 5(9):1119-29. PubMed ID: 23644926 [TBL] [Abstract][Full Text] [Related]
6. Renal transporters in drug development. Morrissey KM; Stocker SL; Wittwer MB; Xu L; Giacomini KM Annu Rev Pharmacol Toxicol; 2013; 53():503-29. PubMed ID: 23140242 [TBL] [Abstract][Full Text] [Related]
7. Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules. Vormann MK; Gijzen L; Hutter S; Boot L; Nicolas A; van den Heuvel A; Vriend J; Ng CP; Nieskens TTG; van Duinen V; de Wagenaar B; Masereeuw R; Suter-Dick L; Trietsch SJ; Wilmer M; Joore J; Vulto P; Lanz HL AAPS J; 2018 Aug; 20(5):90. PubMed ID: 30109442 [TBL] [Abstract][Full Text] [Related]
8. Renal handling of drugs and amino acids after impairment of kidney or liver function--influences of maturity and protective treatment. Fleck C; Bräunlich H Pharmacol Ther; 1995; 67(1):53-77. PubMed ID: 7494861 [TBL] [Abstract][Full Text] [Related]
9. Renal proximal tubular epithelial cells: review of isolation, characterization, and culturing techniques. Mihevc M; Petreski T; Maver U; Bevc S Mol Biol Rep; 2020 Dec; 47(12):9865-9882. PubMed ID: 33170426 [TBL] [Abstract][Full Text] [Related]
10. A simple method for the isolation and detailed characterization of primary human proximal tubule cells for renal replacement therapy. Sánchez-Romero N; Martínez-Gimeno L; Caetano-Pinto P; Saez B; Sánchez-Zalabardo JM; Masereeuw R; Giménez I Int J Artif Organs; 2020 Jan; 43(1):45-57. PubMed ID: 31385550 [TBL] [Abstract][Full Text] [Related]
11. Current State of In vitro Cell-Based Renal Models. Gozalpour E; Fenner KS Curr Drug Metab; 2018; 19(4):310-326. PubMed ID: 29357789 [TBL] [Abstract][Full Text] [Related]
12. Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics. Bajaj P; Chowdhury SK; Yucha R; Kelly EJ; Xiao G Drug Metab Dispos; 2018 Nov; 46(11):1692-1702. PubMed ID: 30076203 [TBL] [Abstract][Full Text] [Related]
13. An integrated in vitro model of perfused tumor and cardiac tissue. Moya M; Tran D; George SC Stem Cell Res Ther; 2013; 4 Suppl 1(Suppl 1):S15. PubMed ID: 24565445 [TBL] [Abstract][Full Text] [Related]
14. Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers. Frohlich EM; Alonso JL; Borenstein JT; Zhang X; Arnaout MA; Charest JL Lab Chip; 2013 Jun; 13(12):2311-9. PubMed ID: 23636129 [TBL] [Abstract][Full Text] [Related]
15. Renal drug-drug interactions: what we have learned and where we are going. Lepist EI; Ray AS Expert Opin Drug Metab Toxicol; 2012 Apr; 8(4):433-48. PubMed ID: 22372422 [TBL] [Abstract][Full Text] [Related]
16. Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling. Brown CD; Sayer R; Windass AS; Haslam IS; De Broe ME; D'Haese PC; Verhulst A Toxicol Appl Pharmacol; 2008 Dec; 233(3):428-38. PubMed ID: 18930752 [TBL] [Abstract][Full Text] [Related]
17. Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. Chang SY; Weber EJ; Sidorenko VS; Chapron A; Yeung CK; Gao C; Mao Q; Shen D; Wang J; Rosenquist TA; Dickman KG; Neumann T; Grollman AP; Kelly EJ; Himmelfarb J; Eaton DL JCI Insight; 2017 Nov; 2(22):. PubMed ID: 29202460 [TBL] [Abstract][Full Text] [Related]
18. Three-dimensional spheroid culture induces apical-basal polarity and the original characteristics of immortalized human renal proximal tubule epithelial cells. Mizuguchi K; Aoki H; Aoyama M; Kawaguchi Y; Waguri-Nagaya Y; Ohte N; Asai K Exp Cell Res; 2021 Jul; 404(1):112630. PubMed ID: 33971195 [TBL] [Abstract][Full Text] [Related]
19. Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles. Ross EJ; Gordon ER; Sothers H; Darji R; Baron O; Haithcock D; Prabhakarpandian B; Pant K; Myers RM; Cooper SJ; Cox NJ Sci Rep; 2021 Jul; 11(1):14053. PubMed ID: 34234242 [TBL] [Abstract][Full Text] [Related]