These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 24571781)

  • 1. Elucidating substrate promiscuity in the human cytochrome 3A4.
    Hayes C; Ansbro D; Kontoyianni M
    J Chem Inf Model; 2014 Mar; 54(3):857-69. PubMed ID: 24571781
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-Based Site of Metabolism (SOM) Prediction of Ligand for CYP3A4 Enzyme: Comparison of Glide XP and Induced Fit Docking (IFD).
    Lokwani DK; Sarkate AP; Karnik KS; Nikalje APG; Seijas JA
    Molecules; 2020 Apr; 25(7):. PubMed ID: 32244772
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Importance of hydrophobic parameters in identifying appropriate pose of CYP substrates in cytochromes.
    Ramesh M; Bharatam PV
    Eur J Med Chem; 2014 Jan; 71():15-23. PubMed ID: 24269512
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Flexibility of human cytochromes P450: molecular dynamics reveals differences between CYPs 3A4, 2C9, and 2A6, which correlate with their substrate preferences.
    Skopalík J; Anzenbacher P; Otyepka M
    J Phys Chem B; 2008 Jul; 112(27):8165-73. PubMed ID: 18598011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops.
    Castrignanò S; D'Avino S; Di Nardo G; Catucci G; Sadeghi SJ; Gilardi G
    Biochim Biophys Acta Proteins Proteom; 2018 Jan; 1866(1):116-125. PubMed ID: 28734977
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4.
    Dai ZR; Ai CZ; Ge GB; He YQ; Wu JJ; Wang JY; Man HZ; Jia Y; Yang L
    Int J Mol Sci; 2015 Jun; 16(7):14677-94. PubMed ID: 26133240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone.
    Gong EC; Chea S; Balupuri A; Kang NS; Chin YW; Choi YH
    Molecules; 2018 Mar; 23(3):. PubMed ID: 29498658
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Flexibility of human cytochrome P450 enzymes: molecular dynamics and spectroscopy reveal important function-related variations.
    Hendrychová T; Anzenbacherová E; Hudeček J; Skopalík J; Lange R; Hildebrandt P; Otyepka M; Anzenbacher P
    Biochim Biophys Acta; 2011 Jan; 1814(1):58-68. PubMed ID: 20656072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of binding modes of ligands to multiple conformations of CYP3A4.
    Teixeira VH; Ribeiro V; Martel PJ
    Biochim Biophys Acta; 2010 Oct; 1804(10):2036-45. PubMed ID: 20601222
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Predicting the binding modes and sites of metabolism of xenobiotics.
    Mukherjee G; Lal Gupta P; Jayaram B
    Mol Biosyst; 2015 Jul; 11(7):1914-24. PubMed ID: 25913019
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Cytochrome P450 3A4 has three Major Conformations: New Clues to Drug Recognition by this Promiscuous Enzyme.
    Benkaidali L; André F; Moroy G; Tangour B; Maurel F; Petitjean M
    Mol Inform; 2017 Oct; 36(10):. PubMed ID: 28685969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New combined model for the prediction of regioselectivity in cytochrome P450/3A4 mediated metabolism.
    Oh WS; Kim DN; Jung J; Cho KH; No KT
    J Chem Inf Model; 2008 Mar; 48(3):591-601. PubMed ID: 18290640
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Understanding the mechanism of cytochrome P450 3A4: recent advances and remaining problems.
    Sevrioukova IF; Poulos TL
    Dalton Trans; 2013 Mar; 42(9):3116-26. PubMed ID: 23018626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computational Investigation of Ligand Binding to the Peripheral Site in CYP3A4: Conformational Dynamics and Inhibitor Discovery.
    Du H; Li J; Cai Y; Zhang H; Liu G; Tang Y; Li W
    J Chem Inf Model; 2017 Mar; 57(3):616-626. PubMed ID: 28221037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of small-molecule binding to cytochrome P450 3A4: flexible docking combined with multidimensional QSAR.
    Lill MA; Dobler M; Vedani A
    ChemMedChem; 2006 Jan; 1(1):73-81. PubMed ID: 16892339
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improved cytochrome P450 3A4 molecular models accurately predict the Phe215 requirement for raloxifene dehydrogenation selectivity.
    Moore CD; Shahrokh K; Sontum SF; Cheatham TE; Yost GS
    Biochemistry; 2010 Oct; 49(41):9011-9. PubMed ID: 20812728
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Improving docking results via reranking of ensembles of ligand poses in multiple X-ray protein conformations with MM-GBSA.
    Greenidge PA; Kramer C; Mozziconacci JC; Sherman W
    J Chem Inf Model; 2014 Oct; 54(10):2697-717. PubMed ID: 25266271
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prediction of cytochrome P450 mediated metabolism.
    Olsen L; Oostenbrink C; Jørgensen FS
    Adv Drug Deliv Rev; 2015 Jun; 86():61-71. PubMed ID: 25958010
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular docking and in vitro evaluations reveal the role of human cytochrome P450 3A4 in the cross-coupling metabolism of phenolic xenobiotics.
    Liu L; Cui H; Huang Y; Yan H; Zhou Y; Wan Y
    Environ Res; 2023 Mar; 220():115256. PubMed ID: 36634892
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Active Site Crowding of Cytochrome P450 3A4 as a Strategy To Alter Its Selectivity.
    Schiavini P; Cheong KJ; Moitessier N; Auclair K
    Chembiochem; 2017 Feb; 18(3):248-252. PubMed ID: 27897366
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.