BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 24575365)

  • 1. Impairment of insulin-stimulated glucose transport and ERK activation by adipocyte-specific knockout of PKC-λ produces a phenotype characterized by diminished adiposity and enhanced insulin suppression of hepatic gluconeogenesis.
    Sajan MP; Jurzak MJ; Samuels VT; Shulman GI; Braun U; Leitges M; Farese RV
    Adipocyte; 2014 Jan; 3(1):19-29. PubMed ID: 24575365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
    Sajan MP; Ivey RA; Lee M; Mastorides S; Jurczak MJ; Samuels VT; Shulman GI; Braun U; Leitges M; Farese RV
    Mol Endocrinol; 2014 Jul; 28(7):1097-107. PubMed ID: 24877563
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein kinase C-lambda knockout in embryonic stem cells and adipocytes impairs insulin-stimulated glucose transport.
    Bandyopadhyay G; Standaert ML; Sajan MP; Kanoh Y; Miura A; Braun U; Kruse F; Leitges M; Farese RV
    Mol Endocrinol; 2004 Feb; 18(2):373-83. PubMed ID: 14615604
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.
    Farese RV; Sajan MP; Yang H; Li P; Mastorides S; Gower WR; Nimal S; Choi CS; Kim S; Shulman GI; Kahn CR; Braun U; Leitges M
    J Clin Invest; 2007 Aug; 117(8):2289-301. PubMed ID: 17641777
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Repletion of atypical protein kinase C following RNA interference-mediated depletion restores insulin-stimulated glucose transport.
    Sajan MP; Rivas J; Li P; Standaert ML; Farese RV
    J Biol Chem; 2006 Jun; 281(25):17466-17473. PubMed ID: 16644736
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thiazolidinedione treatment enhances insulin effects on protein kinase C-zeta /lambda activation and glucose transport in adipocytes of nondiabetic and Goto-Kakizaki type II diabetic rats.
    Kanoh Y; Bandyopadhyay G; Sajan MP; Standaert ML; Farese RV
    J Biol Chem; 2000 Jun; 275(22):16690-6. PubMed ID: 10749857
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ι.
    Sajan MP; Nimal S; Mastorides S; Acevedo-Duncan M; Kahn CR; Fields AP; Braun U; Leitges M; Farese RV
    Metabolism; 2012 Apr; 61(4):459-69. PubMed ID: 22225955
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
    Sajan MP; Ivey RA; Lee MC; Farese RV
    J Lipid Res; 2015 Jan; 56(1):70-80. PubMed ID: 25395359
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
    Sajan MP; Lee MC; Foufelle F; Sajan J; Cleland C; Farese RV
    Cell Signal; 2018 Mar; 43():62-70. PubMed ID: 29269047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of PKC isoforms in glucose transport in 3T3-L1 adipocytes: insignificance of atypical PKC.
    Tsuru M; Katagiri H; Asano T; Yamada T; Ohno S; Ogihara T; Oka Y
    Am J Physiol Endocrinol Metab; 2002 Aug; 283(2):E338-45. PubMed ID: 12110540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.
    Sajan MP; Bandyopadhyay G; Miura A; Standaert ML; Nimal S; Longnus SL; Van Obberghen E; Hainault I; Foufelle F; Kahn R; Braun U; Leitges M; Farese RV
    Am J Physiol Endocrinol Metab; 2010 Feb; 298(2):E179-92. PubMed ID: 19887597
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of transiently expressed atypical (zeta, lambda), conventional (alpha, beta) and novel (delta, epsilon) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific interchangeable effects of protein kinases C-zeta and C-lambda.
    Bandyopadhyay G; Standaert ML; Kikkawa U; Ono Y; Moscat J; Farese RV
    Biochem J; 1999 Feb; 337 ( Pt 3)(Pt 3):461-70. PubMed ID: 9895289
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-zeta/lambda by insulin in vastus lateralis muscles and adipocytes of diabetic rats.
    Kanoh Y; Bandyopadhyay G; Sajan MP; Standaert ML; Farese RV
    Endocrinology; 2001 Apr; 142(4):1595-605. PubMed ID: 11250941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotubes.
    Bandyopadhyay G; Kanoh Y; Sajan MP; Standaert ML; Farese RV
    Endocrinology; 2000 Nov; 141(11):4120-7. PubMed ID: 11089544
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Knockout of PKC alpha enhances insulin signaling through PI3K.
    Leitges M; Plomann M; Standaert ML; Bandyopadhyay G; Sajan MP; Kanoh Y; Farese RV
    Mol Endocrinol; 2002 Apr; 16(4):847-58. PubMed ID: 11923480
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cbl, IRS-1, and IRS-2 mediate effects of rosiglitazone on PI3K, PKC-lambda, and glucose transport in 3T3/L1 adipocytes.
    Standaert ML; Kanoh Y; Sajan MP; Bandyopadhyay G; Farese RV
    Endocrinology; 2002 May; 143(5):1705-16. PubMed ID: 11956152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Okadaic acid activates atypical protein kinase C (zeta/lambda) in rat and 3T3/L1 adipocytes. An apparent requirement for activation of Glut4 translocation and glucose transport.
    Standaert ML; Bandyopadhyay G; Sajan MP; Cong L; Quon MJ; Farese RV
    J Biol Chem; 1999 May; 274(20):14074-8. PubMed ID: 10318822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.
    Standaert ML; Bandyopadhyay G; Perez L; Price D; Galloway L; Poklepovic A; Sajan MP; Cenni V; Sirri A; Moscat J; Toker A; Farese RV
    J Biol Chem; 1999 Sep; 274(36):25308-16. PubMed ID: 10464256
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans.
    Sajan MP; Ivey RA; Farese RV
    Metabolism; 2015 Nov; 64(11):1454-65. PubMed ID: 26386696
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.
    Egawa K; Maegawa H; Shi K; Nakamura T; Obata T; Yoshizaki T; Morino K; Shimizu S; Nishio Y; Suzuki E; Kashiwagi A
    J Biol Chem; 2002 Oct; 277(41):38863-9. PubMed ID: 12147684
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.