235 related articles for article (PubMed ID: 24576206)
1. Measurement of in vivo drug load distribution of cysteine-linked antibody-drug conjugates using microscale liquid chromatography mass spectrometry.
Hengel SM; Sanderson R; Valliere-Douglass J; Nicholas N; Leiske C; Alley SC
Anal Chem; 2014 Apr; 86(7):3420-5. PubMed ID: 24576206
[TBL] [Abstract][Full Text] [Related]
2. A native SEC-MS workflow and validation for analyzing drug-to-antibody ratio and drug load distribution in cysteine-linked antibody-drug conjugates.
Wu G; Yu C; Yin S; Du J; Zhang Y; Fu Z; Wang L; Wang J
J Chromatogr B Analyt Technol Biomed Life Sci; 2024 Jul; 1241():124167. PubMed ID: 38823148
[TBL] [Abstract][Full Text] [Related]
3. Conformation and dynamics of interchain cysteine-linked antibody-drug conjugates as revealed by hydrogen/deuterium exchange mass spectrometry.
Pan LY; Salas-Solano O; Valliere-Douglass JF
Anal Chem; 2014 Mar; 86(5):2657-64. PubMed ID: 24512515
[TBL] [Abstract][Full Text] [Related]
4. A rapid on-line method for mass spectrometric confirmation of a cysteine-conjugated antibody-drug-conjugate structure using multidimensional chromatography.
Birdsall RE; Shion H; Kotch FW; Xu A; Porter TJ; Chen W
MAbs; 2015; 7(6):1036-44. PubMed ID: 26305867
[TBL] [Abstract][Full Text] [Related]
5. Approaches to Interchain Cysteine-Linked ADC Characterization by Mass Spectrometry.
Valliere-Douglass JF; Hengel SM; Pan LY
Mol Pharm; 2015 Jun; 12(6):1774-83. PubMed ID: 25474122
[TBL] [Abstract][Full Text] [Related]
6. Characterization of antibody drug conjugate positional isomers at cysteine residues by peptide mapping LC-MS analysis.
Janin-Bussat MC; Dillenbourg M; Corvaia N; Beck A; Klinguer-Hamour C
J Chromatogr B Analyt Technol Biomed Life Sci; 2015 Feb; 981-982():9-13. PubMed ID: 25596378
[TBL] [Abstract][Full Text] [Related]
7. Native intact mass determination of antibodies conjugated with monomethyl Auristatin E and F at interchain cysteine residues.
Valliere-Douglass JF; McFee WA; Salas-Solano O
Anal Chem; 2012 Mar; 84(6):2843-9. PubMed ID: 22384990
[TBL] [Abstract][Full Text] [Related]
8. Practical approaches for overcoming challenges in heightened characterization of antibody-drug conjugates with new methodologies and ultrahigh-resolution mass spectrometry.
Friese OV; Smith JN; Brown PW; Rouse JC
MAbs; 2018 Apr; 10(3):335-345. PubMed ID: 29393747
[TBL] [Abstract][Full Text] [Related]
9. Immunoprecipitation middle-up LC-MS for in vivo drug-to-antibody ratio determination for antibody-drug conjugates.
Davis JA; Kagan M; Read J; Walles M; Hatsis P
Bioanalysis; 2017 Oct; 9(20):1535-1549. PubMed ID: 29072490
[TBL] [Abstract][Full Text] [Related]
10. Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.
Debaene F; Boeuf A; Wagner-Rousset E; Colas O; Ayoub D; Corvaïa N; Van Dorsselaer A; Beck A; Cianférani S
Anal Chem; 2014 Nov; 86(21):10674-83. PubMed ID: 25270580
[TBL] [Abstract][Full Text] [Related]
11. [The Characterization of Drug-to-Antibody Ratio and Isoforms of ADCs Using LC and MS Technologies].
Iizuka R; Kotch F; Xu A; Porter T; Shion H; Birdsall R; Chen W
Yakugaku Zasshi; 2017; 137(5):525-528. PubMed ID: 28458283
[TBL] [Abstract][Full Text] [Related]
12. Native-MS Analysis of Monoclonal Antibody Conjugates by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.
Campuzano IDG; Netirojjanakul C; Nshanian M; Lippens JL; Kilgour DPA; Van Orden S; Loo JA
Anal Chem; 2018 Jan; 90(1):745-751. PubMed ID: 29193956
[TBL] [Abstract][Full Text] [Related]
13. Accurate determination of drug-to-antibody ratio of interchain cysteine-linked antibody-drug conjugates by LC-HRMS.
Li K; Zhang Z; Lin ZJ; Shi H; Ma Y
Anal Bioanal Chem; 2020 Feb; 412(4):833-840. PubMed ID: 31872274
[TBL] [Abstract][Full Text] [Related]
14. Development of a native nanoelectrospray mass spectrometry method for determination of the drug-to-antibody ratio of antibody-drug conjugates.
Chen J; Yin S; Wu Y; Ouyang J
Anal Chem; 2013 Feb; 85(3):1699-704. PubMed ID: 23289544
[TBL] [Abstract][Full Text] [Related]
15. Intact quantitation of cysteine-conjugated antibody-drug conjugates using native mass spectrometry.
Li Y; Wang Y; Shenoy VM; Niu S; Jenkins GJ; Sarvaiya H
Rapid Commun Mass Spectrom; 2024 Aug; 38(15):e9774. PubMed ID: 38812280
[TBL] [Abstract][Full Text] [Related]
16. Analysis of ADCs by Native Mass Spectrometry.
Hernandez-Alba O; Ehkirch A; Beck A; Cianférani S
Methods Mol Biol; 2020; 2078():197-211. PubMed ID: 31643058
[TBL] [Abstract][Full Text] [Related]
17. Native size-exclusion chromatography-mass spectrometry: suitability for antibody-drug conjugate drug-to-antibody ratio quantitation across a range of chemotypes and drug-loading levels.
Jones J; Pack L; Hunter JH; Valliere-Douglass JF
MAbs; 2020; 12(1):1682895. PubMed ID: 31769727
[TBL] [Abstract][Full Text] [Related]
18. Characterization of the drug-to-antibody ratio distribution for antibody-drug conjugates in plasma/serum.
Xu K; Liu L; Dere R; Mai E; Erickson R; Hendricks A; Lin K; Junutula JR; Kaur S
Bioanalysis; 2013 May; 5(9):1057-71. PubMed ID: 23641696
[TBL] [Abstract][Full Text] [Related]
19. Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics.
Thompson P; Fleming R; Bezabeh B; Huang F; Mao S; Chen C; Harper J; Zhong H; Gao X; Yu XQ; Hinrichs MJ; Reed M; Kamal A; Strout P; Cho S; Woods R; Hollingsworth RE; Dixit R; Wu H; Gao C; Dimasi N
J Control Release; 2016 Aug; 236():100-16. PubMed ID: 27327768
[TBL] [Abstract][Full Text] [Related]
20. A size exclusion-reversed phase two dimensional-liquid chromatography methodology for stability and small molecule related species in antibody drug conjugates.
Li Y; Gu C; Gruenhagen J; Zhang K; Yehl P; Chetwyn NP; Medley CD
J Chromatogr A; 2015 May; 1393():81-8. PubMed ID: 25818558
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
