BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 24576853)

  • 1. Optimized lentiviral vectors for HIV gene therapy: multiplexed expression of small RNAs and inclusion of MGMT(P140K) drug resistance gene.
    Chung J; Scherer LJ; Gu A; Gardner AM; Torres-Coronado M; Epps EW; Digiusto DL; Rossi JJ
    Mol Ther; 2014 May; 22(5):952-63. PubMed ID: 24576853
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.
    Zhao H; Pestina TI; Nasimuzzaman M; Mehta P; Hargrove PW; Persons DA
    Blood; 2009 Jun; 113(23):5747-56. PubMed ID: 19365082
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Co-expression of MGMT(P140K) and alpha-L-iduronidase in primary hepatocytes from mucopolysaccharidosis type I mice enables efficient selection with metabolic correction.
    Wang D; Worsham DN; Pan D
    J Gene Med; 2008 Mar; 10(3):249-59. PubMed ID: 18076130
    [TBL] [Abstract][Full Text] [Related]  

  • 4. F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
    Maier P; Heckmann D; Spier I; Laufs S; Zucknick M; Allgayer H; Fruehauf S; Zeller WJ; Wenz F
    Cancer Gene Ther; 2012 Nov; 19(11):802-10. PubMed ID: 23037811
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endogenous MCM7 microRNA cluster as a novel platform to multiplex small interfering and nucleolar RNAs for combinational HIV-1 gene therapy.
    Chung J; Zhang J; Li H; Ouellet DL; DiGiusto DL; Rossi JJ
    Hum Gene Ther; 2012 Nov; 23(11):1200-8. PubMed ID: 22834872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency.
    Trobridge GD; Beard BC; Wu RA; Ironside C; Malik P; Kiem HP
    PLoS One; 2012; 7(9):e45173. PubMed ID: 23028826
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Imaging stem cell-derived persistent foci after in vivo selection of lentiviral MGMT-P140K transduced murine bone marrow cells.
    Lin Y; Cheung P; Roth JC; Wilson DL; Gerson SL
    Mol Ther; 2011 Jul; 19(7):1342-52. PubMed ID: 21304493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells.
    Schambach A; Baum C
    DNA Repair (Amst); 2007 Aug; 6(8):1187-96. PubMed ID: 17482894
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation.
    Hacke K; Falahati R; Flebbe-Rehwaldt L; Kasahara N; Gaensler KM
    Immunol Res; 2009; 44(1-3):112-26. PubMed ID: 19048410
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.
    Trobridge GD; Wu RA; Beard BC; Chiu SY; Muñoz NM; von Laer D; Rossi JJ; Kiem HP
    PLoS One; 2009 Nov; 4(11):e7693. PubMed ID: 19888329
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Optimizing glioblastoma temozolomide chemotherapy employing lentiviral-based anti-MGMT shRNA technology.
    Viel T; Monfared P; Schelhaas S; Fricke IB; Kuhlmann MT; Fraefel C; Jacobs AH
    Mol Ther; 2013 Mar; 21(3):570-9. PubMed ID: 23319055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vivo selection of autologous MGMT gene-modified cells following reduced-intensity conditioning with BCNU and temozolomide in the dog model.
    Gori JL; Beard BC; Ironside C; Karponi G; Kiem HP
    Cancer Gene Ther; 2012 Aug; 19(8):523-9. PubMed ID: 22627392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection.
    Anderson J; Akkina R
    Retrovirology; 2005 Aug; 2():53. PubMed ID: 16109172
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinical Trial of MGMT(P140K) Gene Therapy in the Treatment of Pediatric Patients with Brain Tumors.
    Kramer B; Singh R; Wischusen J; Dent R; Rush A; Middlemiss S; Ching YW; Alexander IE; McCowage G
    Hum Gene Ther; 2018 Aug; 29(8):874-885. PubMed ID: 29385852
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy.
    Anderson JS; Javien J; Nolta JA; Bauer G
    Mol Ther; 2009 Dec; 17(12):2103-14. PubMed ID: 19690520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Construction of a novel gene therapy lentiviral vector for drug resistant selection and detection in vivo].
    Xu C; Gu Y; Hou W; Cheng T; Zhang T; Que Y; Gao S; Zhang J; Han J; Xia N
    Sheng Wu Gong Cheng Xue Bao; 2008 Feb; 24(2):256-61. PubMed ID: 18464610
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection.
    Milsom MD; Williams DA
    DNA Repair (Amst); 2007 Aug; 6(8):1210-21. PubMed ID: 17482893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro.
    Zielske SP; Gerson SL
    Mol Ther; 2002 Apr; 5(4):381-7. PubMed ID: 11945064
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression.
    Falahati R; Zhang J; Flebbe-Rehwaldt L; Shi Y; Gerson SL; Gaensler KM
    Mol Ther; 2012 Nov; 20(11):2180-9. PubMed ID: 22871662
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Efficiency and safety of O⁶-methylguanine DNA methyltransferase (MGMT(P140K))-mediated in vivo selection in a humanized mouse model.
    Phaltane R; Haemmerle R; Rothe M; Modlich U; Moritz T
    Hum Gene Ther; 2014 Feb; 25(2):144-55. PubMed ID: 24218991
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.