441 related articles for article (PubMed ID: 24581546)
1. Discovery of 2-pyridone derivatives as potent HIV-1 NNRTIs using molecular hybridization based on crystallographic overlays.
Chen W; Zhan P; Rai D; De Clercq E; Pannecouque C; Balzarini J; Zhou Z; Liu H; Liu X
Bioorg Med Chem; 2014 Mar; 22(6):1863-72. PubMed ID: 24581546
[TBL] [Abstract][Full Text] [Related]
2. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays.
Huang B; Wang X; Liu X; Chen Z; Li W; Sun S; Liu H; Daelemans D; De Clercq E; Pannecouque C; Zhan P; Liu X
Bioorg Med Chem; 2017 Aug; 25(16):4397-4406. PubMed ID: 28659246
[TBL] [Abstract][Full Text] [Related]
4. New pyridinone derivatives as potent HIV-1 nonnucleoside reverse transcriptase inhibitors.
Le Van K; Cauvin C; de Walque S; Georges B; Boland S; Martinelli V; Demonté D; Durant F; Hevesi L; Van Lint C
J Med Chem; 2009 Jun; 52(12):3636-43. PubMed ID: 19469474
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.
Chen X; Zhan P; Liu X; Cheng Z; Meng C; Shao S; Pannecouque C; De Clercq E; Liu X
Bioorg Med Chem; 2012 Jun; 20(12):3856-64. PubMed ID: 22591854
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, biological evaluation and molecular modeling of 4,6-diarylpyrimidines and diarylbenzenes as novel non-nucleosides HIV-1 reverse transcriptase inhibitors.
Ribone SR; Leen V; Madrid M; Dehaen W; Daelemans D; Pannecouque C; Briñón MC
Eur J Med Chem; 2012 Dec; 58():485-92. PubMed ID: 23159806
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization.
Liu Z; Chen W; Zhan P; De Clercq E; Pannecouque C; Liu X
Eur J Med Chem; 2014 Nov; 87():52-62. PubMed ID: 25240095
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of 3-benzyloxy-linked pyrimidinylphenylamine derivatives as potent HIV-1 NNRTIs.
Rai D; Chen W; Tian Y; Chen X; Zhan P; De Clercq E; Pannecouque C; Balzarini J; Liu X
Bioorg Med Chem; 2013 Dec; 21(23):7398-405. PubMed ID: 24134904
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Zhang J; Zhan P; Wu J; Li Z; Jiang Y; Ge W; Pannecouque C; De Clercq E; Liu X
Bioorg Med Chem; 2011 Jul; 19(14):4366-76. PubMed ID: 21683601
[TBL] [Abstract][Full Text] [Related]
10. Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.
Huang B; Li C; Chen W; Liu T; Yu M; Fu L; Sun Y; Liu H; De Clercq E; Pannecouque C; Balzarini J; Zhan P; Liu X
Eur J Med Chem; 2015 Mar; 92():754-65. PubMed ID: 25626145
[TBL] [Abstract][Full Text] [Related]
11. Fused heterocyclic compounds bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 1: design, synthesis and biological evaluation of novel 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives.
Tian Y; Du D; Rai D; Wang L; Liu H; Zhan P; De Clercq E; Pannecouque C; Liu X
Bioorg Med Chem; 2014 Apr; 22(7):2052-9. PubMed ID: 24631361
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs.
Gu SX; Yang SQ; He QQ; Ma XD; Chen FE; Dai HF; Clercq ED; Balzarini J; Pannecouque C
Bioorg Med Chem; 2011 Dec; 19(23):7093-9. PubMed ID: 22037050
[TBL] [Abstract][Full Text] [Related]
13. Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing.
Zhao T; Meng Q; Kang D; Ji J; De Clercq E; Pannecouque C; Liu X; Zhan P
Eur J Med Chem; 2019 Nov; 182():111619. PubMed ID: 31434039
[TBL] [Abstract][Full Text] [Related]
14. Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors from arylthioacetanilide structural motif.
Li W; Li X; De Clercq E; Zhan P; Liu X
Eur J Med Chem; 2015 Sep; 102():167-79. PubMed ID: 26276432
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, structure-activity relationships, and docking studies of N-phenylarylformamide derivatives (PAFAs) as non-nucleoside HIV reverse transcriptase inhibitors.
Ma XD; He QQ; Zhang X; Yang SQ; Yang LM; Gu SX; Zheng YT; Chen FE; Dai HF
Eur J Med Chem; 2012 Dec; 58():504-12. PubMed ID: 23164656
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket.
Yang J; Chen W; Kang D; Lu X; Li X; Liu Z; Huang B; Daelemans D; Pannecouque C; De Clercq E; Zhan P; Liu X
Eur J Med Chem; 2016 Feb; 109():294-304. PubMed ID: 26802545
[TBL] [Abstract][Full Text] [Related]
17. Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines.
Huang B; Liang X; Li C; Chen W; Liu T; Li X; Sun Y; Fu L; Liu H; De Clercq E; Pannecouque C; Zhan P; Liu X
Eur J Med Chem; 2015 Mar; 93():330-7. PubMed ID: 25707013
[TBL] [Abstract][Full Text] [Related]
18. Discovery of piperidine-linked pyridine analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Chen X; Li Y; Ding S; Balzarini J; Pannecouque C; De Clercq E; Liu H; Liu X
ChemMedChem; 2013 Jul; 8(7):1117-26. PubMed ID: 23650275
[TBL] [Abstract][Full Text] [Related]
19. Diaryl ethers with carboxymethoxyphenacyl motif as potent HIV-1 reverse transcriptase inhibitors with improved solubility.
Frączek T; Kamiński R; Krakowiak A; Naessens E; Verhasselt B; Paneth P
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):9-16. PubMed ID: 29098886
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological activity of naphthyl-substituted (B-ring) benzophenone derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Ma XD; Zhang X; Dai HF; Yang SQ; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
Bioorg Med Chem; 2011 Aug; 19(15):4601-7. PubMed ID: 21719299
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
