184 related articles for article (PubMed ID: 24582612)
1. Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase.
Fang L; Hou S; Xue L; Zheng F; Zhan CG
Chem Biol Interact; 2014 May; 214():18-25. PubMed ID: 24582612
[TBL] [Abstract][Full Text] [Related]
2. Substrate selectivity of high-activity mutants of human butyrylcholinesterase.
Hou S; Xue L; Yang W; Fang L; Zheng F; Zhan CG
Org Biomol Chem; 2013 Nov; 11(43):7477-85. PubMed ID: 24077614
[TBL] [Abstract][Full Text] [Related]
3. Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine.
Xue L; Hou S; Tong M; Fang L; Chen X; Jin Z; Tai HH; Zheng F; Zhan CG
Biochem J; 2013 Aug; 453(3):447-54. PubMed ID: 23849058
[TBL] [Abstract][Full Text] [Related]
4. Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine.
Yang W; Xue L; Fang L; Chen X; Zhan CG
Chem Biol Interact; 2010 Sep; 187(1-3):148-52. PubMed ID: 20060817
[TBL] [Abstract][Full Text] [Related]
5. Design of high-activity mutants of human butyrylcholinesterase against (-)-cocaine: structural and energetic factors affecting the catalytic efficiency.
Zheng F; Yang W; Xue L; Hou S; Liu J; Zhan CG
Biochemistry; 2010 Oct; 49(42):9113-9. PubMed ID: 20886866
[TBL] [Abstract][Full Text] [Related]
6. Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine.
Xue L; Hou S; Yang W; Fang L; Zheng F; Zhan CG
Chem Biol Interact; 2013 Mar; 203(1):57-62. PubMed ID: 22917637
[TBL] [Abstract][Full Text] [Related]
7. Rational design of an enzyme mutant for anti-cocaine therapeutics.
Zheng F; Zhan CG
J Comput Aided Mol Des; 2008 Sep; 22(9):661-71. PubMed ID: 17989928
[TBL] [Abstract][Full Text] [Related]
8. Computational redesign of human butyrylcholinesterase for anticocaine medication.
Pan Y; Gao D; Yang W; Cho H; Yang G; Tai HH; Zhan CG
Proc Natl Acad Sci U S A; 2005 Nov; 102(46):16656-61. PubMed ID: 16275916
[TBL] [Abstract][Full Text] [Related]
9. Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine.
Xue L; Ko MC; Tong M; Yang W; Hou S; Fang L; Liu J; Zheng F; Woods JH; Tai HH; Zhan CG
Mol Pharmacol; 2011 Feb; 79(2):290-7. PubMed ID: 20971807
[TBL] [Abstract][Full Text] [Related]
10. Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase.
Chen X; Huang X; Geng L; Xue L; Hou S; Zheng X; Brimijoin S; Zheng F; Zhan CG
Biochem J; 2015 Mar; 466(2):243-51. PubMed ID: 25486543
[TBL] [Abstract][Full Text] [Related]
11. A model of glycosylated human butyrylcholinesterase.
Fang L; Zheng F; Zhan CG
Mol Biosyst; 2014 Feb; 10(2):348-54. PubMed ID: 24327294
[TBL] [Abstract][Full Text] [Related]
12. Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity.
Duysen EG; Bartels CF; Lockridge O
J Pharmacol Exp Ther; 2002 Aug; 302(2):751-8. PubMed ID: 12130740
[TBL] [Abstract][Full Text] [Related]
13. Free energy perturbation simulation on transition states and high-activity mutants of human butyrylcholinesterase for (-)-cocaine hydrolysis.
Yang W; Pan Y; Fang L; Gao D; Zheng F; Zhan CG
J Phys Chem B; 2010 Aug; 114(33):10889-96. PubMed ID: 20677742
[TBL] [Abstract][Full Text] [Related]
14. Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase.
Sun H; Shen ML; Pang YP; Lockridge O; Brimijoin S
J Pharmacol Exp Ther; 2002 Aug; 302(2):710-6. PubMed ID: 12130735
[TBL] [Abstract][Full Text] [Related]
15. Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biological Half-Life.
Cai Y; Zhou S; Jin Z; Wei H; Shang L; Deng J; Zhan CG; Zheng F
AAPS J; 2019 Nov; 22(1):5. PubMed ID: 31754920
[TBL] [Abstract][Full Text] [Related]
16. Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase.
Yang W; Pan Y; Zheng F; Cho H; Tai HH; Zhan CG
Biophys J; 2009 Mar; 96(5):1931-8. PubMed ID: 19254552
[TBL] [Abstract][Full Text] [Related]
17. Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity.
Larrimore KE; Barcus M; Kannan L; Gao Y; Zhan CG; Brimijoin S; Mor T
Chem Biol Interact; 2013 Mar; 203(1):217-20. PubMed ID: 23000451
[TBL] [Abstract][Full Text] [Related]
18. Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene.
Zheng X; Chen X; Zhang T; Zhan M; Zhan CG; Zheng F
Org Biomol Chem; 2020 Mar; 18(10):1968-1977. PubMed ID: 32101217
[TBL] [Abstract][Full Text] [Related]
19. Model of human butyrylcholinesterase tetramer by homology modeling and dynamics simulation.
Pan Y; Muzyka JL; Zhan CG
J Phys Chem B; 2009 May; 113(18):6543-52. PubMed ID: 19402731
[TBL] [Abstract][Full Text] [Related]
20. Kinetic characterization of human butyrylcholinesterase mutants for the hydrolysis of cocaethylene.
Hou S; Zhan M; Zheng X; Zhan CG; Zheng F
Biochem J; 2014 Jun; 460(3):447-57. PubMed ID: 24870023
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
