These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
751 related articles for article (PubMed ID: 24582753)
1. Over-expression of FoxM1 is associated with adverse prognosis and FLT3-ITD in acute myeloid leukemia. Liu LL; Zhang DH; Mao X; Zhang XH; Zhang B Biochem Biophys Res Commun; 2014 Mar; 446(1):280-5. PubMed ID: 24582753 [TBL] [Abstract][Full Text] [Related]
2. Internal tandem duplication of FLT3 deregulates proliferation and differentiation and confers resistance to the FLT3 inhibitor AC220 by Up-regulating RUNX1 expression in hematopoietic cells. Hirade T; Abe M; Onishi C; Taketani T; Yamaguchi S; Fukuda S Int J Hematol; 2016 Jan; 103(1):95-106. PubMed ID: 26590920 [TBL] [Abstract][Full Text] [Related]
3. Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation. Kapoor S; Natarajan K; Baldwin PR; Doshi KA; Lapidus RG; Mathias TJ; Scarpa M; Trotta R; Davila E; Kraus M; Huszar D; Tron AE; Perrotti D; Baer MR Clin Cancer Res; 2018 Jan; 24(1):234-247. PubMed ID: 29074603 [No Abstract] [Full Text] [Related]
4. FLT3 inhibition upregulates HDAC8 via FOXO to inactivate p53 and promote maintenance of FLT3-ITD+ acute myeloid leukemia. Long J; Jia MY; Fang WY; Chen XJ; Mu LL; Wang ZY; Shen Y; Xiang RF; Wang LN; Wang L; Jiang CH; Jiang JL; Zhang WJ; Sun YD; Chang L; Gao WH; Wang Y; Li JM; Hong DL; Liang AB; Hu J Blood; 2020 Apr; 135(17):1472-1483. PubMed ID: 32315388 [TBL] [Abstract][Full Text] [Related]
5. NFATc1 as a therapeutic target in FLT3-ITD-positive AML. Metzelder SK; Michel C; von Bonin M; Rehberger M; Hessmann E; Inselmann S; Solovey M; Wang Y; Sohlbach K; Brendel C; Stiewe T; Charles J; Ten Haaf A; Ellenrieder V; Neubauer A; Gattenlöhner S; Bornhäuser M; Burchert A Leukemia; 2015 Jul; 29(7):1470-7. PubMed ID: 25976987 [TBL] [Abstract][Full Text] [Related]
9. Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia. Zhang W; Konopleva M; Shi YX; McQueen T; Harris D; Ling X; Estrov Z; Quintás-Cardama A; Small D; Cortes J; Andreeff M J Natl Cancer Inst; 2008 Feb; 100(3):184-98. PubMed ID: 18230792 [TBL] [Abstract][Full Text] [Related]
10. Quizartinib (AC220): a promising option for acute myeloid leukemia. Zhou F; Ge Z; Chen B Drug Des Devel Ther; 2019; 13():1117-1125. PubMed ID: 31114157 [TBL] [Abstract][Full Text] [Related]
11. Cabozantinib is selectively cytotoxic in acute myeloid leukemia cells with FLT3-internal tandem duplication (FLT3-ITD). Lu JW; Wang AN; Liao HA; Chen CY; Hou HA; Hu CY; Tien HF; Ou DL; Lin LI Cancer Lett; 2016 Jul; 376(2):218-25. PubMed ID: 27060207 [TBL] [Abstract][Full Text] [Related]
12. FLT3-ITD transduces autonomous growth signals during its biosynthetic trafficking in acute myelogenous leukemia cells. Yamawaki K; Shiina I; Murata T; Tateyama S; Maekawa Y; Niwa M; Shimonaka M; Okamoto K; Suzuki T; Nishida T; Abe R; Obata Y Sci Rep; 2021 Nov; 11(1):22678. PubMed ID: 34811450 [TBL] [Abstract][Full Text] [Related]
13. Homoharringtonine synergizes with quizartinib in FLT3-ITD acute myeloid leukemia by targeting FLT3-AKT-c-Myc pathway. Wang F; Huang J; Guo T; Zheng Y; Zhang L; Zhang D; Wang F; Naren D; Cui Y; Liu X; Qu Y; Luo H; Yang Y; Wei H; Guo Y Biochem Pharmacol; 2021 Jun; 188():114538. PubMed ID: 33831397 [TBL] [Abstract][Full Text] [Related]
14. Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity. Yi H; Zeng D; Shen Z; Liao J; Wang X; Liu Y; Zhang X; Kong P Oncotarget; 2016 Jun; 7(26):40387-40397. PubMed ID: 27248172 [TBL] [Abstract][Full Text] [Related]
15. The role of quizartinib in the treatment of acute myeloid leukemia. Ostronoff F; Estey E Expert Opin Investig Drugs; 2013 Dec; 22(12):1659-69. PubMed ID: 24070241 [TBL] [Abstract][Full Text] [Related]
16. High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in Sharawat SK; Raina V; Kumar L; Sharma A; Bakhshi R; Vishnubhatla S; Gupta R; Bakhshi S Indian J Med Res; 2016 May; 143(Supplement):S11-S16. PubMed ID: 27748272 [TBL] [Abstract][Full Text] [Related]
17. Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia. Smith CC; Wang Q; Chin CS; Salerno S; Damon LE; Levis MJ; Perl AE; Travers KJ; Wang S; Hunt JP; Zarrinkar PP; Schadt EE; Kasarskis A; Kuriyan J; Shah NP Nature; 2012 Apr; 485(7397):260-3. PubMed ID: 22504184 [TBL] [Abstract][Full Text] [Related]
18. MZH29 is a novel potent inhibitor that overcomes drug resistance FLT3 mutations in acute myeloid leukemia. Xu B; Zhao Y; Wang X; Gong P; Ge W Leukemia; 2017 Apr; 31(4):913-921. PubMed ID: 27773927 [TBL] [Abstract][Full Text] [Related]
19. Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors. Maifrede S; Nieborowska-Skorska M; Sullivan-Reed K; Dasgupta Y; Podszywalow-Bartnicka P; Le BV; Solecka M; Lian Z; Belyaeva EA; Nersesyan A; Machnicki MM; Toma M; Chatain N; Rydzanicz M; Zhao H; Jelinek J; Piwocka K; Sliwinski T; Stoklosa T; Ploski R; Fischer T; Sykes SM; Koschmieder S; Bullinger L; Valent P; Wasik MA; Huang J; Skorski T Blood; 2018 Jul; 132(1):67-77. PubMed ID: 29784639 [TBL] [Abstract][Full Text] [Related]
20. Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells. Stölzel F; Steudel C; Oelschlägel U; Mohr B; Koch S; Ehninger G; Thiede C Ann Hematol; 2010 Jul; 89(7):653-62. PubMed ID: 20119833 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]