BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 24584936)

  • 1. Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA).
    Herva ME; Zibaee S; Fraser G; Barker RA; Goedert M; Spillantini MG
    J Biol Chem; 2014 Apr; 289(17):11897-11905. PubMed ID: 24584936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA.
    Becker K; Wang X; Vander Stel K; Chu Y; Kordower J; Ma J
    Mol Neurobiol; 2018 Nov; 55(11):8728-8737. PubMed ID: 29589283
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preserved proteinase K-resistant core after amplification of alpha-synuclein aggregates: Implication to disease-related structural study.
    Yoshinaga S; Yamanaka T; Miyazaki H; Okuzumi A; Hiyama A; Murayama S; Nukina N
    Biochem Biophys Res Commun; 2020 Feb; 522(3):655-661. PubMed ID: 31785806
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Seeded propagation of α-synuclein aggregation in mouse brain using protein misfolding cyclic amplification.
    Nicot S; Verchère J; Bélondrade M; Mayran C; Bétemps D; Bougard D; Baron T
    FASEB J; 2019 Nov; 33(11):12073-12086. PubMed ID: 31370680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy.
    Shahnawaz M; Mukherjee A; Pritzkow S; Mendez N; Rabadia P; Liu X; Hu B; Schmeichel A; Singer W; Wu G; Tsai AL; Shirani H; Nilsson KPR; Low PA; Soto C
    Nature; 2020 Feb; 578(7794):273-277. PubMed ID: 32025029
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amplification of distinct α-synuclein fibril conformers through protein misfolding cyclic amplification.
    Jung BC; Lim YJ; Bae EJ; Lee JS; Choi MS; Lee MK; Lee HJ; Kim YS; Lee SJ
    Exp Mol Med; 2017 Apr; 49(4):e314. PubMed ID: 28386127
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
    Pujols J; Peña-Díaz S; Lázaro DF; Peccati F; Pinheiro F; González D; Carija A; Navarro S; Conde-Giménez M; García J; Guardiola S; Giralt E; Salvatella X; Sancho J; Sodupe M; Outeiro TF; Dalfó E; Ventura S
    Proc Natl Acad Sci U S A; 2018 Oct; 115(41):10481-10486. PubMed ID: 30249646
    [TBL] [Abstract][Full Text] [Related]  

  • 8. α-Synuclein aggregation at low concentrations.
    Afitska K; Fucikova A; Shvadchak VV; Yushchenko DA
    Biochim Biophys Acta Proteins Proteom; 2019; 1867(7-8):701-709. PubMed ID: 31096048
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protease-Sensitive and -Resistant Forms of Human and Murine Alpha-Synucleins in Distinct Brain Regions of Transgenic Mice (M83) Expressing the Human Mutated A53T Protein.
    Bétemps D; Arsac JN; Nicot S; Canal D; Tlili H; Belondrade M; Morignat E; Verchère J; Gaillard D; Bruyère-Ostells L; Mayran C; Lakhdar L; Bougard D; Baron T
    Biomolecules; 2023 Dec; 13(12):. PubMed ID: 38136658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Detection of alpha-synuclein aggregates in gastrointestinal biopsies by protein misfolding cyclic amplification.
    Fenyi A; Leclair-Visonneau L; Clairembault T; Coron E; Neunlist M; Melki R; Derkinderen P; Bousset L
    Neurobiol Dis; 2019 Sep; 129():38-43. PubMed ID: 31078683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The neurotransmitter serotonin interrupts α-synuclein amyloid maturation.
    Falsone SF; Leitinger G; Karner A; Kungl AJ; Kosol S; Cappai R; Zangger K
    Biochim Biophys Acta; 2011 May; 1814(5):553-61. PubMed ID: 21376144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ligand Profiling as a Diagnostic Tool to Differentiate Patient-Derived α-Synuclein Polymorphs.
    Chisholm TS; Melki R; Hunter CA
    ACS Chem Neurosci; 2024 May; 15(10):2080-2088. PubMed ID: 38690599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Detection of Misfolded α-Synuclein Aggregates in Cerebrospinal Fluid by the Protein Misfolding Cyclic Amplification Platform.
    Concha-Marambio L; Shahnawaz M; Soto C
    Methods Mol Biol; 2019; 1948():35-44. PubMed ID: 30771168
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors.
    Pujols J; Peña-Díaz S; Conde-Giménez M; Pinheiro F; Navarro S; Sancho J; Ventura S
    Int J Mol Sci; 2017 Mar; 18(3):. PubMed ID: 28257086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of α-Synuclein Amyloid Fibril Elongation by Blocking Fibril Ends.
    Shvadchak VV; Afitska K; Yushchenko DA
    Angew Chem Int Ed Engl; 2018 May; 57(20):5690-5694. PubMed ID: 29575453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A simple in vitro assay for assessing the efficacy, mechanisms and kinetics of anti-prion fibril compounds.
    Ladner-Keay CL; Ross L; Perez-Pineiro R; Zhang L; Bjorndahl TC; Cashman N; Wishart DS
    Prion; 2018; 12(5-6):280-300. PubMed ID: 30223704
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Single Molecule Fingerprinting Reveals Different Amplification Properties of α-Synuclein Oligomers and Preformed Fibrils in Seeding Assay.
    Lau D; Magnan C; Hill K; Cooper A; Gambin Y; Sierecki E
    ACS Chem Neurosci; 2022 Apr; 13(7):883-896. PubMed ID: 35286811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Eye lens crystallin proteins inhibit the autocatalytic amyloid amplification nature of mature α-synuclein fibrils.
    Gaspar R; Garting T; Stradner A
    PLoS One; 2020; 15(6):e0235198. PubMed ID: 32598365
    [TBL] [Abstract][Full Text] [Related]  

  • 19. α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation.
    Bartels T; Choi JG; Selkoe DJ
    Nature; 2011 Aug; 477(7362):107-10. PubMed ID: 21841800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. α-Synuclein Fibrils Exhibit Gain of Toxic Function, Promoting Tau Aggregation and Inhibiting Microtubule Assembly.
    Oikawa T; Nonaka T; Terada M; Tamaoka A; Hisanaga S; Hasegawa M
    J Biol Chem; 2016 Jul; 291(29):15046-56. PubMed ID: 27226637
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.