These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 24589581)

  • 1. Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides.
    Ward AJ; Norrbom M; Chun S; Bennett CF; Rigo F
    Nucleic Acids Res; 2014 May; 42(9):5871-9. PubMed ID: 24589581
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination.
    Lai F; Damle SS; Ling KK; Rigo F
    Mol Cell; 2020 Mar; 77(5):1032-1043.e4. PubMed ID: 31924447
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RNA Reduction and Hepatotoxic Potential Caused by Non-Gapmer Antisense Oligonucleotides.
    Hori SI; Mitsuoka Y; Kugimiya A
    Nucleic Acid Ther; 2019 Feb; 29(1):44-50. PubMed ID: 30508397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway.
    Liang XH; Nichols JG; Hsu CW; Vickers TA; Crooke ST
    Nucleic Acids Res; 2019 Jul; 47(13):6900-6916. PubMed ID: 31165876
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus.
    Liang XH; Sun H; Nichols JG; Crooke ST
    Mol Ther; 2017 Sep; 25(9):2075-2092. PubMed ID: 28663102
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Some ASOs that bind in the coding region of mRNAs and induce RNase H1 cleavage can cause increases in the pre-mRNAs that may blunt total activity.
    Liang XH; Nichols JG; De Hoyos CL; Crooke ST
    Nucleic Acids Res; 2020 Sep; 48(17):9840-9858. PubMed ID: 32870273
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.
    Huang L; Low A; Damle SS; Keenan MM; Kuntz S; Murray SF; Monia BP; Guo S
    Genome Biol; 2018 Jan; 19(1):4. PubMed ID: 29334995
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.
    Burel SA; Hart CE; Cauntay P; Hsiao J; Machemer T; Katz M; Watt A; Bui HH; Younis H; Sabripour M; Freier SM; Hung G; Dan A; Prakash TP; Seth PP; Swayze EE; Bennett CF; Crooke ST; Henry SP
    Nucleic Acids Res; 2016 Mar; 44(5):2093-109. PubMed ID: 26553810
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Defining the factors that contribute to on-target specificity of antisense oligonucleotides.
    Lima WF; Vickers TA; Nichols J; Li C; Crooke ST
    PLoS One; 2014; 9(7):e101752. PubMed ID: 25072142
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination.
    Lee JS; Mendell JT
    Mol Cell; 2020 Mar; 77(5):1044-1054.e3. PubMed ID: 31924448
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms.
    Vickers TA; Crooke ST
    PLoS One; 2014; 9(10):e108625. PubMed ID: 25299183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides.
    Wilton SD; Lloyd F; Carville K; Fletcher S; Honeyman K; Agrawal S; Kole R
    Neuromuscul Disord; 1999 Jul; 9(5):330-8. PubMed ID: 10407856
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival.
    Wittkopp N; Huntzinger E; Weiler C; Saulière J; Schmidt S; Sonawane M; Izaurralde E
    Mol Cell Biol; 2009 Jul; 29(13):3517-28. PubMed ID: 19414594
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of combinations of gapmer antisense oligonucleotides on the target reduction.
    Yanagidaira M; Yoshioka K; Nagata T; Nakao S; Miyata K; Yokota T
    Mol Biol Rep; 2023 Apr; 50(4):3539-3546. PubMed ID: 36787053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Estimated number of off-target candidate sites for antisense oligonucleotides in human mRNA sequences.
    Yoshida T; Naito Y; Sasaki K; Uchida E; Sato Y; Naito M; Kawanishi T; Obika S; Inoue T
    Genes Cells; 2018 Jun; 23(6):448-455. PubMed ID: 29667281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs.
    Liang XH; Nichols JG; Sun H; Crooke ST
    Nucleic Acids Res; 2018 Jan; 46(1):293-313. PubMed ID: 29165591
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway.
    Chen CY; Shyu AB
    Mol Cell Biol; 2003 Jul; 23(14):4805-13. PubMed ID: 12832468
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hybridization-mediated off-target effects of splice-switching antisense oligonucleotides.
    Scharner J; Ma WK; Zhang Q; Lin KT; Rigo F; Bennett CF; Krainer AR
    Nucleic Acids Res; 2020 Jan; 48(2):802-816. PubMed ID: 31802121
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing.
    Rigo F; Hua Y; Chun SJ; Prakash TP; Krainer AR; Bennett CF
    Nat Chem Biol; 2012 Apr; 8(6):555-61. PubMed ID: 22504300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity.
    Dyer PDR; Shepherd TR; Gollings AS; Shorter SA; Gorringe-Pattrick MAM; Tang CK; Cattoz BN; Baillie L; Griffiths PC; Richardson SCW
    J Control Release; 2015 Dec; 220(Pt A):316-328. PubMed ID: 26546271
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.