These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 24591589)

  • 1. Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity.
    Matlack KE; Tardiff DF; Narayan P; Hamamichi S; Caldwell KA; Caldwell GA; Lindquist S
    Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4013-8. PubMed ID: 24591589
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism.
    Tardiff DF; Brown LE; Yan X; Trilles R; Jui NT; Barrasa MI; Caldwell KA; Caldwell GA; Schaus SE; Lindquist S
    ACS Chem Neurosci; 2017 Sep; 8(9):2039-2055. PubMed ID: 28628299
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stabilization of nontoxic Aβ-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease.
    Ryan TM; Roberts BR; McColl G; Hare DJ; Doble PA; Li QX; Lind M; Roberts AM; Mertens HD; Kirby N; Pham CL; Hinds MG; Adlard PA; Barnham KJ; Curtain CC; Masters CL
    J Neurosci; 2015 Feb; 35(7):2871-84. PubMed ID: 25698727
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
    LeVine H; Ding Q; Walker JA; Voss RS; Augelli-Szafran CE
    Neurosci Lett; 2009 Nov; 465(1):99-103. PubMed ID: 19664688
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
    Treusch S; Hamamichi S; Goodman JL; Matlack KE; Chung CY; Baru V; Shulman JM; Parrado A; Bevis BJ; Valastyan JS; Han H; Lindhagen-Persson M; Reiman EM; Evans DA; Bennett DA; Olofsson A; DeJager PL; Tanzi RE; Caldwell KA; Caldwell GA; Lindquist S
    Science; 2011 Dec; 334(6060):1241-5. PubMed ID: 22033521
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of clioquinol on metal-triggered amyloid-beta aggregation revisited.
    Mancino AM; Hindo SS; Kochi A; Lim MH
    Inorg Chem; 2009 Oct; 48(20):9596-8. PubMed ID: 19817493
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clioquinol reduces zinc accumulation in neuritic plaques and inhibits the amyloidogenic pathway in AβPP/PS1 transgenic mouse brain.
    Wang T; Wang CY; Shan ZY; Teng WP; Wang ZY
    J Alzheimers Dis; 2012; 29(3):549-59. PubMed ID: 22269164
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic redistribution of metal ions to treat Alzheimer's disease.
    Crouch PJ; Barnham KJ
    Acc Chem Res; 2012 Sep; 45(9):1604-11. PubMed ID: 22747493
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide.
    Raman B; Ban T; Yamaguchi K; Sakai M; Kawai T; Naiki H; Goto Y
    J Biol Chem; 2005 Apr; 280(16):16157-62. PubMed ID: 15718230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
    White AR; Du T; Laughton KM; Volitakis I; Sharples RA; Xilinas ME; Hoke DE; Holsinger RM; Evin G; Cherny RA; Hill AF; Barnham KJ; Li QX; Bush AI; Masters CL
    J Biol Chem; 2006 Jun; 281(26):17670-80. PubMed ID: 16648635
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metal chelator decreases Alzheimer beta-amyloid plaques.
    Gouras GK; Beal MF
    Neuron; 2001 Jun; 30(3):641-2. PubMed ID: 11430794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Utility of an improved model of amyloid-beta (Aβ₁₋₄₂) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease.
    McColl G; Roberts BR; Pukala TL; Kenche VB; Roberts CM; Link CD; Ryan TM; Masters CL; Barnham KJ; Bush AI; Cherny RA
    Mol Neurodegener; 2012 Nov; 7():57. PubMed ID: 23171715
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits.
    Izzo NJ; Staniszewski A; To L; Fa M; Teich AF; Saeed F; Wostein H; Walko T; Vaswani A; Wardius M; Syed Z; Ravenscroft J; Mozzoni K; Silky C; Rehak C; Yurko R; Finn P; Look G; Rishton G; Safferstein H; Miller M; Johanson C; Stopa E; Windisch M; Hutter-Paier B; Shamloo M; Arancio O; LeVine H; Catalano SM
    PLoS One; 2014; 9(11):e111898. PubMed ID: 25390368
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity.
    Chen J; Armstrong AH; Koehler AN; Hecht MH
    J Am Chem Soc; 2010 Dec; 132(47):17015-22. PubMed ID: 21062056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
    Caragounis A; Du T; Filiz G; Laughton KM; Volitakis I; Sharples RA; Cherny RA; Masters CL; Drew SC; Hill AF; Li QX; Crouch PJ; Barnham KJ; White AR
    Biochem J; 2007 Nov; 407(3):435-50. PubMed ID: 17680773
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alzheimer's disease & metals: therapeutic opportunities.
    Kenche VB; Barnham KJ
    Br J Pharmacol; 2011 May; 163(2):211-9. PubMed ID: 21232050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans.
    Pretsch D; Rollinger JM; Schmid A; Genov M; Wöhrer T; Krenn L; Moloney M; Kasture A; Hummel T; Pretsch A
    Sci Rep; 2020 Jul; 10(1):11707. PubMed ID: 32678125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fucoidan inhibits amyloid-β-induced toxicity in transgenic Caenorhabditis elegans by reducing the accumulation of amyloid-β and decreasing the production of reactive oxygen species.
    Wang X; Yi K; Zhao Y
    Food Funct; 2018 Jan; 9(1):552-560. PubMed ID: 29260173
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Clioquinol rescues yeast cells from Aβ42 toxicity via the inhibition of oxidative damage.
    Zheng Q; Zhu H; Lv C; Zhu Z; Cui H; Fan Z; Sun J; Huang Z; Shi P
    Biotechnol J; 2024 Jun; 19(6):e2300662. PubMed ID: 38863126
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers.
    Diomede L; Cassata G; Fiordaliso F; Salio M; Ami D; Natalello A; Doglia SM; De Luigi A; Salmona M
    Neurobiol Dis; 2010 Nov; 40(2):424-31. PubMed ID: 20637283
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.