These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
260 related articles for article (PubMed ID: 24592208)
1. Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism. Dugovic C; Shelton JE; Yun S; Bonaventure P; Shireman BT; Lovenberg TW Front Neurosci; 2014; 8():28. PubMed ID: 24592208 [TBL] [Abstract][Full Text] [Related]
2. Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat. Dugovic C; Shelton JE; Aluisio LE; Fraser IC; Jiang X; Sutton SW; Bonaventure P; Yun S; Li X; Lord B; Dvorak CA; Carruthers NI; Lovenberg TW J Pharmacol Exp Ther; 2009 Jul; 330(1):142-51. PubMed ID: 19363060 [TBL] [Abstract][Full Text] [Related]
3. Selective Inhibition of Orexin-2 Receptors Prevents Stress-Induced ACTH Release in Mice. Yun S; Wennerholm M; Shelton JE; Bonaventure P; Letavic MA; Shireman BT; Lovenberg TW; Dugovic C Front Behav Neurosci; 2017; 11():83. PubMed ID: 28533747 [TBL] [Abstract][Full Text] [Related]
4. Orexin in sleep, addiction and more: is the perfect insomnia drug at hand? Hoyer D; Jacobson LH Neuropeptides; 2013 Dec; 47(6):477-88. PubMed ID: 24215799 [TBL] [Abstract][Full Text] [Related]
5. Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man. Gotter AL; Forman MS; Harrell CM; Stevens J; Svetnik V; Yee KL; Li X; Roecker AJ; Fox SV; Tannenbaum PL; Garson SL; Lepeleire ID; Calder N; Rosen L; Struyk A; Coleman PJ; Herring WJ; Renger JJ; Winrow CJ Sci Rep; 2016 Jun; 6():27147. PubMed ID: 27256922 [TBL] [Abstract][Full Text] [Related]
6. Orexin OX Jacobson LH; Chen S; Mir S; Hoyer D Curr Top Behav Neurosci; 2017; 33():105-136. PubMed ID: 27909987 [TBL] [Abstract][Full Text] [Related]
7. OX2R-selective orexin agonism is sufficient to ameliorate cataplexy and sleep/wake fragmentation without inducing drug-seeking behavior in mouse model of narcolepsy. Yamamoto H; Nagumo Y; Ishikawa Y; Irukayama-Tomobe Y; Namekawa Y; Nemoto T; Tanaka H; Takahashi G; Tokuda A; Saitoh T; Nagase H; Funato H; Yanagisawa M PLoS One; 2022; 17(7):e0271901. PubMed ID: 35867683 [TBL] [Abstract][Full Text] [Related]
8. Induction of narcolepsy-like symptoms by orexin receptor antagonists in mice. Kaushik MK; Aritake K; Cherasse Y; Imanishi A; Kanbayashi T; Urade Y; Yanagisawa M Sleep; 2021 Aug; 44(8):. PubMed ID: 33609365 [TBL] [Abstract][Full Text] [Related]
9. Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Willie JT; Chemelli RM; Sinton CM; Tokita S; Williams SC; Kisanuki YY; Marcus JN; Lee C; Elmquist JK; Kohlmeier KA; Leonard CS; Richardson JA; Hammer RE; Yanagisawa M Neuron; 2003 Jun; 38(5):715-30. PubMed ID: 12797957 [TBL] [Abstract][Full Text] [Related]
10. TAK-925, an orexin 2 receptor-selective agonist, shows robust wake-promoting effects in mice. Yukitake H; Fujimoto T; Ishikawa T; Suzuki A; Shimizu Y; Rikimaru K; Ito M; Suzuki M; Kimura H Pharmacol Biochem Behav; 2019 Dec; 187():172794. PubMed ID: 31654653 [TBL] [Abstract][Full Text] [Related]
11. Distinct effects of IPSU and suvorexant on mouse sleep architecture. Hoyer D; Dürst T; Fendt M; Jacobson LH; Betschart C; Hintermann S; Behnke D; Cotesta S; Laue G; Ofner S; Legangneux E; Gee CE Front Neurosci; 2013; 7():235. PubMed ID: 24368893 [TBL] [Abstract][Full Text] [Related]
12. Design and Synthesis of Orexin 1 Receptor-Selective Agonists. Iio K; Hashimoto K; Nagumo Y; Amezawa M; Hasegawa T; Yamamoto N; Kutsumura N; Takeuchi K; Ishikawa Y; Yamamoto H; Tokuda A; Sato T; Uchida Y; Inoue A; Tanimura R; Yanagisawa M; Nagase H; Saitoh T J Med Chem; 2023 Apr; 66(8):5453-5464. PubMed ID: 37043436 [TBL] [Abstract][Full Text] [Related]
13. TAK-994, a Novel Orally Available Brain-Penetrant Orexin 2 Receptor-Selective Agonist, Suppresses Fragmentation of Wakefulness and Cataplexy-Like Episodes in Mouse Models of Narcolepsy. Ishikawa T; Hara H; Kawano A; Tohyama K; Kajita Y; Miyanohana Y; Koike T; Kimura H J Pharmacol Exp Ther; 2023 Jun; 385(3):193-204. PubMed ID: 37001988 [TBL] [Abstract][Full Text] [Related]
14. Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice. Etori K; Saito YC; Tsujino N; Sakurai T Front Neurosci; 2014; 8():8. PubMed ID: 24550770 [TBL] [Abstract][Full Text] [Related]
15. Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia. Bonaventure P; Shelton J; Yun S; Nepomuceno D; Sutton S; Aluisio L; Fraser I; Lord B; Shoblock J; Welty N; Chaplan SR; Aguilar Z; Halter R; Ndifor A; Koudriakova T; Rizzolio M; Letavic M; Carruthers NI; Lovenberg T; Dugovic C J Pharmacol Exp Ther; 2015 Sep; 354(3):471-82. PubMed ID: 26177655 [TBL] [Abstract][Full Text] [Related]
16. Optical probing of orexin/hypocretin receptor antagonists. Li SB; Nevárez N; Giardino WJ; de Lecea L Sleep; 2018 Oct; 41(10):. PubMed ID: 30060151 [TBL] [Abstract][Full Text] [Related]
17. Knockdown of orexin type 2 receptor in the lateral pontomesencephalic tegmentum of rats increases REM sleep. Chen L; McKenna JT; Bolortuya Y; Brown RE; McCarley RW Eur J Neurosci; 2013 Mar; 37(6):957-63. PubMed ID: 23282008 [TBL] [Abstract][Full Text] [Related]
18. Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice. Roundtree HM; Simeone TA; Johnson C; Matthews SA; Samson KK; Simeone KA Sleep; 2016 Feb; 39(2):357-68. PubMed ID: 26446112 [TBL] [Abstract][Full Text] [Related]
19. Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy. Ito H; Fukatsu N; Rahaman SM; Mukai Y; Izawa S; Ono D; Kilduff TS; Yamanaka A Proc Natl Acad Sci U S A; 2023 Oct; 120(41):e2301951120. PubMed ID: 37796986 [TBL] [Abstract][Full Text] [Related]
20. Dual orexin receptor antagonists increase sleep and cataplexy in wild type mice. Mahoney CE; Mochizuki T; Scammell TE Sleep; 2020 Jun; 43(6):. PubMed ID: 31830270 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]