BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 24597548)

  • 1. Synthetic FXR agonist GW4064 is a modulator of multiple G protein-coupled receptors.
    Singh N; Yadav M; Singh AK; Kumar H; Dwivedi SK; Mishra JS; Gurjar A; Manhas A; Chandra S; Yadav PN; Jagavelu K; Siddiqi MI; Trivedi AK; Chattopadhyay N; Sanyal S
    Mol Endocrinol; 2014 May; 28(5):659-73. PubMed ID: 24597548
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α.
    Dwivedi SK; Singh N; Kumari R; Mishra JS; Tripathi S; Banerjee P; Shah P; Kukshal V; Tyagi AM; Gaikwad AN; Chaturvedi RK; Mishra DP; Trivedi AK; Sanyal S; Chattopadhyay N; Ramachandran R; Siddiqi MI; Bandyopadhyay A; Arora A; Lundåsen T; Anakk SP; Moore DD; Sanyal S
    Mol Endocrinol; 2011 Jun; 25(6):922-32. PubMed ID: 21493670
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression.
    Zhang S; Pan X; Jeong H
    Drug Metab Dispos; 2015 May; 43(5):743-8. PubMed ID: 25725071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties.
    Flesch D; Gabler M; Lill A; Gomez RC; Steri R; Schneider G; Stark H; Schubert-Zsilavecz M; Merk D
    Bioorg Med Chem; 2015 Jul; 23(13):3490-8. PubMed ID: 25934227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adiponectin determines farnesoid X receptor agonism-mediated cardioprotection against post-infarction remodelling and dysfunction.
    Xia Y; Zhang F; Zhao S; Li Y; Chen X; Gao E; Xu X; Xiong Z; Zhang X; Zhang J; Zhao H; Wang W; Wang H; Guo Y; Liu Y; Li C; Wang S; Zhang L; Yan W; Tao L
    Cardiovasc Res; 2018 Aug; 114(10):1335-1349. PubMed ID: 29668847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Farnesoid X Receptor Agonist GW4064 Inhibits Aromatase and ERβ Expression in Human Endometriotic Stromal Cells.
    Wu PL; Zeng C; Zhou YF; Yin L; Yu XL; Xue Q
    Reprod Sci; 2019 Aug; 26(8):1111-1120. PubMed ID: 30428773
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FXR agonist GW4064 improves liver and intestinal pathology and alters bile acid metabolism in rats undergoing small intestinal resection.
    Cao Y; Xiao Y; Zhou K; Yan J; Wang P; Yan W; Cai W
    Am J Physiol Gastrointest Liver Physiol; 2019 Aug; 317(2):G108-G115. PubMed ID: 30920307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of Farnesoid X Receptor impairs the tumor-promoting function of breast cancer-associated fibroblasts.
    Barone I; Vircillo V; Giordano C; Gelsomino L; Győrffy B; Tarallo R; Rinaldi A; Bruno G; Caruso A; Romeo F; Bonofiglio D; Andò S; Catalano S
    Cancer Lett; 2018 Nov; 437():89-99. PubMed ID: 30176263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A rapid administration of GW4064 inhibits the NLRP3 inflammasome activation independent of farnesoid X receptor agonism.
    Xie S; Guo C; Chi Z; Huang B; Wu Y; Wang D; Xia D
    FEBS Lett; 2017 Sep; 591(18):2836-2847. PubMed ID: 28787755
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β.
    Noh K; Kim YM; Kim YW; Kim SG
    Drug Metab Dispos; 2011 Aug; 39(8):1451-9. PubMed ID: 21596890
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064.
    Moscovitz JE; Kong B; Buckley K; Buckley B; Guo GL; Aleksunes LM
    Toxicol Appl Pharmacol; 2016 Nov; 310():60-67. PubMed ID: 27609522
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes.
    Cai K; Sewer MB
    Biochem J; 2013 Sep; 454(2):267-74. PubMed ID: 23767959
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relevance of FXR-p62/SQSTM1 pathway for survival and protection of mouse hepatocytes and liver, especially with steatosis.
    Haga S; Yimin ; Ozaki M
    BMC Gastroenterol; 2017 Jan; 17(1):9. PubMed ID: 28086800
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GW4064, a farnesoid X receptor agonist, upregulates adipokine expression in preadipocytes and HepG2 cells.
    Xin XM; Zhong MX; Yang GL; Peng Y; Zhang YL; Zhu W
    World J Gastroenterol; 2014 Nov; 20(42):15727-35. PubMed ID: 25400456
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Knockdown of ATP8B1 expression leads to specific downregulation of the bile acid sensor FXR in HepG2 cells: effect of the FXR agonist GW4064.
    Martínez-Fernández P; Hierro L; Jara P; Alvarez L
    Am J Physiol Gastrointest Liver Physiol; 2009 May; 296(5):G1119-29. PubMed ID: 19228886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation.
    Yao J; Zhou CS; Ma X; Fu BQ; Tao LS; Chen M; Xu YP
    World J Gastroenterol; 2014 Oct; 20(39):14430-41. PubMed ID: 25339829
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activated FXR Inhibits Leptin Signaling and Counteracts Tumor-promoting Activities of Cancer-Associated Fibroblasts in Breast Malignancy.
    Giordano C; Barone I; Vircillo V; Panza S; Malivindi R; Gelsomino L; Pellegrino M; Rago V; Mauro L; Lanzino M; Panno ML; Bonofiglio D; Catalano S; Andò S
    Sci Rep; 2016 Feb; 6():21782. PubMed ID: 26899873
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets.
    Moraes LA; Unsworth AJ; Vaiyapuri S; Ali MS; Sasikumar P; Sage T; Flora GD; Bye AP; Kriek N; Dorchies E; Molendi-Coste O; Dombrowicz D; Staels B; Bishop-Bailey D; Gibbins JM
    Arterioscler Thromb Vasc Biol; 2016 Dec; 36(12):2324-2333. PubMed ID: 27758768
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor.
    Greimel T; Jahnel J; Pohl S; Strini T; Tischitz M; Meier-Allard N; Holasek S; Meinel K; Aguiriano-Moser V; Zobel J; Haidl H; Gallistl S; Panzitt K; Wagner M; Schlagenhauf A
    Lab Invest; 2021 Oct; 101(10):1394-1402. PubMed ID: 34145381
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unbinding pathways of GW4064 from human farnesoid X receptor as revealed by molecular dynamics simulations.
    Li W; Fu J; Cheng F; Zheng M; Zhang J; Liu G; Tang Y
    J Chem Inf Model; 2012 Nov; 52(11):3043-52. PubMed ID: 23101941
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.