505 related articles for article (PubMed ID: 24599296)
1. A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies.
Ramaiahgari SC; den Braver MW; Herpers B; Terpstra V; Commandeur JN; van de Water B; Price LS
Arch Toxicol; 2014 May; 88(5):1083-95. PubMed ID: 24599296
[TBL] [Abstract][Full Text] [Related]
2. HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism.
Rebelo SP; Costa R; Estrada M; Shevchenko V; Brito C; Alves PM
Arch Toxicol; 2015 Aug; 89(8):1347-58. PubMed ID: 25107451
[TBL] [Abstract][Full Text] [Related]
3. Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.
Herzog N; Hansen M; Miethbauer S; Schmidtke KU; Anderer U; Lupp A; Sperling S; Seehofer D; Damm G; Scheibner K; Küpper JH
Cell Biol Int; 2016 Mar; 40(3):341-53. PubMed ID: 26715207
[TBL] [Abstract][Full Text] [Related]
4. High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.
Hiemstra S; Ramaiahgari SC; Wink S; Callegaro G; Coonen M; Meerman J; Jennen D; van den Nieuwendijk K; Dankers A; Snoeys J; de Bont H; Price L; van de Water B
Arch Toxicol; 2019 Oct; 93(10):2895-2911. PubMed ID: 31552476
[TBL] [Abstract][Full Text] [Related]
5. Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.
Bierwolf J; Lutgehetmann M; Deichmann S; Erbes J; Volz T; Dandri M; Cohen S; Nashan B; Pollok JM
Tissue Eng Part A; 2012 Jul; 18(13-14):1443-53. PubMed ID: 22612238
[TBL] [Abstract][Full Text] [Related]
6. Human liver cell spheroids in extended perfusion bioreactor culture for repeated-dose drug testing.
Tostões RM; Leite SB; Serra M; Jensen J; Björquist P; Carrondo MJ; Brito C; Alves PM
Hepatology; 2012 Apr; 55(4):1227-36. PubMed ID: 22031499
[TBL] [Abstract][Full Text] [Related]
7. Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening.
Wang Z; Li W; Jing H; Ding M; Fu G; Yuan T; Huang W; Dai M; Tang D; Zeng M; Chen Y; Zhang H; Zhu X; Peng Y; Li Q; Yu WF; Yan HX; Zhai B
Theranostics; 2019; 9(22):6690-6705. PubMed ID: 31588244
[No Abstract] [Full Text] [Related]
8. A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity.
Kostadinova R; Boess F; Applegate D; Suter L; Weiser T; Singer T; Naughton B; Roth A
Toxicol Appl Pharmacol; 2013 Apr; 268(1):1-16. PubMed ID: 23352505
[TBL] [Abstract][Full Text] [Related]
9. Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.
Tolosa L; Gómez-Lechón MJ; López S; Guzmán C; Castell JV; Donato MT; Jover R
Toxicol Sci; 2016 Jul; 152(1):214-29. PubMed ID: 27208088
[TBL] [Abstract][Full Text] [Related]
10. Spheroid-based three-dimensional liver-on-a-chip to investigate hepatocyte-hepatic stellate cell interactions and flow effects.
Lee SA; No da Y; Kang E; Ju J; Kim DS; Lee SH
Lab Chip; 2013 Sep; 13(18):3529-37. PubMed ID: 23657720
[TBL] [Abstract][Full Text] [Related]
11. Reprint of: A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies.
Shah UK; Mallia JO; Singh N; Chapman KE; Doak SH; Jenkins GJS
Mutat Res Genet Toxicol Environ Mutagen; 2018 Oct; 834():35-41. PubMed ID: 30173862
[TBL] [Abstract][Full Text] [Related]
12. 3D spheroid cultures improve the metabolic gene expression profiles of HepaRG cells.
Takahashi Y; Hori Y; Yamamoto T; Urashima T; Ohara Y; Tanaka H
Biosci Rep; 2015 May; 35(3):. PubMed ID: 26182370
[TBL] [Abstract][Full Text] [Related]
13. HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.
Tolosa L; Gómez-Lechón MJ; Pérez-Cataldo G; Castell JV; Donato MT
Arch Toxicol; 2013 Jun; 87(6):1115-27. PubMed ID: 23397584
[TBL] [Abstract][Full Text] [Related]
14. Peptide nanofiber hydrogel induces formation of bile canaliculi structures in three-dimensional hepatic cell culture.
Malinen MM; Palokangas H; Yliperttula M; Urtti A
Tissue Eng Part A; 2012 Dec; 18(23-24):2418-25. PubMed ID: 22712588
[TBL] [Abstract][Full Text] [Related]
15. 3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies.
Gunness P; Mueller D; Shevchenko V; Heinzle E; Ingelman-Sundberg M; Noor F
Toxicol Sci; 2013 May; 133(1):67-78. PubMed ID: 23377618
[TBL] [Abstract][Full Text] [Related]
16. Development of complex-shaped liver multicellular spheroids as a human-based model for nanoparticle toxicity assessment in vitro.
Dubiak-Szepietowska M; Karczmarczyk A; Jönsson-Niedziółka M; Winckler T; Feller KH
Toxicol Appl Pharmacol; 2016 Mar; 294():78-85. PubMed ID: 26825373
[TBL] [Abstract][Full Text] [Related]
17. Generation of proliferating human hepatocytes using Upcyte® technology: characterisation and applications in induction and cytotoxicity assays.
Burkard A; Dähn C; Heinz S; Zutavern A; Sonntag-Buck V; Maltman D; Przyborski S; Hewitt NJ; Braspenning J
Xenobiotica; 2012 Oct; 42(10):939-56. PubMed ID: 22524704
[TBL] [Abstract][Full Text] [Related]
18. Galactosylated reversible hydrogels as scaffold for HepG2 spheroid generation.
Wu Y; Zhao Z; Guan Y; Zhang Y
Acta Biomater; 2014 May; 10(5):1965-74. PubMed ID: 24382516
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of drug toxicity with hepatocytes cultured in a micro-space cell culture system.
Nakamura K; Mizutani R; Sanbe A; Enosawa S; Kasahara M; Nakagawa A; Ejiri Y; Murayama N; Miyamoto Y; Torii T; Kusakawa S; Yamauchi J; Fukuda M; Yamazaki H; Tanoue A
J Biosci Bioeng; 2011 Jan; 111(1):78-84. PubMed ID: 20837398
[TBL] [Abstract][Full Text] [Related]
20. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.
Schulz C; Kammerer S; Küpper JH
Clin Hemorheol Microcirc; 2019; 73(1):249-260. PubMed ID: 31561354
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]