BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 24599328)

  • 21. The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75.
    Zhang DW; Yan HL; Xu XS; Xu L; Yin ZH; Chang S; Luo H
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):906-912. PubMed ID: 32228103
    [TBL] [Abstract][Full Text] [Related]  

  • 22. LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection.
    Debyser Z; Bruggemans A; Van Belle S; Janssens J; Christ F
    Adv Exp Med Biol; 2021; 1322():97-114. PubMed ID: 34258738
    [TBL] [Abstract][Full Text] [Related]  

  • 23. New scaffolds of natural origin as Integrase-LEDGF/p75 interaction inhibitors: virtual screening and activity assays.
    De Luca L; Morreale F; Christ F; Debyser Z; Ferro S; Gitto R
    Eur J Med Chem; 2013 Oct; 68():405-11. PubMed ID: 23994868
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.
    Slaughter A; Jurado KA; Deng N; Feng L; Kessl JJ; Shkriabai N; Larue RC; Fadel HJ; Patel PA; Jena N; Fuchs JR; Poeschla E; Levy RM; Engelman A; Kvaratskhelia M
    Retrovirology; 2014 Nov; 11():100. PubMed ID: 25421939
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction.
    Zhang FH; Debnath B; Xu ZL; Yang LM; Song LR; Zheng YT; Neamati N; Long YQ
    Eur J Med Chem; 2017 Jan; 125():1051-1063. PubMed ID: 27810592
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking.
    Hu G; Li X; Sun X; Lu W; Liu G; Huang J; Shen X; Tang Y
    J Mol Model; 2012 Dec; 18(12):4995-5003. PubMed ID: 22733274
    [TBL] [Abstract][Full Text] [Related]  

  • 27. LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs.
    Schrijvers R; De Rijck J; Demeulemeester J; Adachi N; Vets S; Ronen K; Christ F; Bushman FD; Debyser Z; Gijsbers R
    PLoS Pathog; 2012; 8(3):e1002558. PubMed ID: 22396646
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
    De Luca L; Barreca ML; Ferro S; Christ F; Iraci N; Gitto R; Monforte AM; Debyser Z; Chimirri A
    ChemMedChem; 2009 Aug; 4(8):1311-6. PubMed ID: 19565598
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Evaluation of a flavonoid library for inhibition of interaction of HIV-1 integrase with human LEDGF/p75 towards a structure-activity relationship.
    Yin ZH; Yan HL; Pan Y; Zhang DW; Yan X
    Ann Med; 2022 Dec; 54(1):1590-1600. PubMed ID: 35658757
    [No Abstract]   [Full Text] [Related]  

  • 30. Optimized binding of substituted quinoline ALLINIs within the HIV-1 integrase oligomer.
    Sun J; Patel K; Hume J; Pigza JA; Donahue MG; Kessl JJ
    J Biol Chem; 2021; 296():100363. PubMed ID: 33539919
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Study of Structure-active Relationship for Inhibitors of HIV-1 Integrase LEDGF/p75 Interaction by Machine Learning Methods.
    Li Y; Wu Y; Yan A
    Mol Inform; 2017 Jul; 36(7):. PubMed ID: 28244220
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase.
    Zheng Y; Ao Z; Jayappa KD; Yao X
    Virol J; 2010 Mar; 7():68. PubMed ID: 20331877
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors.
    Singh PK; Li W; Bedwell GJ; Fadel HJ; Poeschla EM; Engelman AN
    Viruses; 2022 Aug; 14(9):. PubMed ID: 36146690
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A Conformational Escape Reaction of HIV-1 against an Allosteric Integrase Inhibitor.
    Nakamura T; Nakamura T; Amano M; Miyakawa T; Yamagata Y; Matsuoka M; Nakata H
    J Virol; 2020 Sep; 94(19):. PubMed ID: 32611758
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Allosteric inhibition of HIV-1 integrase activity.
    Engelman A; Kessl JJ; Kvaratskhelia M
    Curr Opin Chem Biol; 2013 Jun; 17(3):339-45. PubMed ID: 23647983
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibitors of the interactions between HIV-1 IN and the cofactor LEDGF/p75.
    De Luca L; Ferro S; Morreale F; De Grazia S; Chimirri A
    ChemMedChem; 2011 Jul; 6(7):1184-91. PubMed ID: 21506277
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.
    Serrao E; Xu ZL; Debnath B; Christ F; Debyser Z; Long YQ; Neamati N
    Bioorg Med Chem; 2013 Oct; 21(19):5963-72. PubMed ID: 23985689
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.
    Maehigashi T; Ahn S; Kim UI; Lindenberger J; Oo A; Koneru PC; Mahboubi B; Engelman AN; Kvaratskhelia M; Kim K; Kim B
    PLoS Pathog; 2021 Jul; 17(7):e1009671. PubMed ID: 34293041
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integrase.
    Agharbaoui FE; Hoyte AC; Ferro S; Gitto R; Buemi MR; Fuchs JR; Kvaratskhelia M; De Luca L
    Eur J Med Chem; 2016 Nov; 123():673-683. PubMed ID: 27517812
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Identification of the LEDGF/p75 binding site in HIV-1 integrase.
    Busschots K; Voet A; De Maeyer M; Rain JC; Emiliani S; Benarous R; Desender L; Debyser Z; Christ F
    J Mol Biol; 2007 Feb; 365(5):1480-92. PubMed ID: 17137594
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.