These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
112 related articles for article (PubMed ID: 24601221)
1. More antitumor efficacy of the PI3K inhibitor GDC-0941 in breast cancer with PIK3CA mutation or HER2 amplification status in vitro. Zheng J; Wang H; Yao J; Zou X Pharmazie; 2014 Jan; 69(1):38-42. PubMed ID: 24601221 [TBL] [Abstract][Full Text] [Related]
2. The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells. Zheng J; Zou X; Yao J Chemotherapy; 2012; 58(4):273-81. PubMed ID: 23006739 [TBL] [Abstract][Full Text] [Related]
3. Roles of BIM induction and survivin downregulation in lapatinib-induced apoptosis in breast cancer cells with HER2 amplification. Tanizaki J; Okamoto I; Fumita S; Okamoto W; Nishio K; Nakagawa K Oncogene; 2011 Sep; 30(39):4097-106. PubMed ID: 21499301 [TBL] [Abstract][Full Text] [Related]
4. Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. O'Brien C; Wallin JJ; Sampath D; GuhaThakurta D; Savage H; Punnoose EA; Guan J; Berry L; Prior WW; Amler LC; Belvin M; Friedman LS; Lackner MR Clin Cancer Res; 2010 Jul; 16(14):3670-83. PubMed ID: 20453058 [TBL] [Abstract][Full Text] [Related]
5. Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer. Yang W; Hosford SR; Dillon LM; Shee K; Liu SC; Bean JR; Salphati L; Pang J; Zhang X; Nannini MA; Demidenko E; Bates D; Lewis LD; Marotti JD; Eastman AR; Miller TW Clin Cancer Res; 2016 May; 22(9):2250-60. PubMed ID: 26733612 [TBL] [Abstract][Full Text] [Related]
6. Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941. Junttila TT; Akita RW; Parsons K; Fields C; Lewis Phillips GD; Friedman LS; Sampath D; Sliwkowski MX Cancer Cell; 2009 May; 15(5):429-40. PubMed ID: 19411071 [TBL] [Abstract][Full Text] [Related]
7. Suppression of HER2/HER3-mediated growth of breast cancer cells with combinations of GDC-0941 PI3K inhibitor, trastuzumab, and pertuzumab. Yao E; Zhou W; Lee-Hoeflich ST; Truong T; Haverty PM; Eastham-Anderson J; Lewin-Koh N; Gunter B; Belvin M; Murray LJ; Friedman LS; Sliwkowski MX; Hoeflich KP Clin Cancer Res; 2009 Jun; 15(12):4147-56. PubMed ID: 19509167 [TBL] [Abstract][Full Text] [Related]
8. GDC-0941, a novel class I selective PI3K inhibitor, enhances the efficacy of docetaxel in human breast cancer models by increasing cell death in vitro and in vivo. Wallin JJ; Guan J; Prior WW; Lee LB; Berry L; Belmont LD; Koeppen H; Belvin M; Friedman LS; Sampath D Clin Cancer Res; 2012 Jul; 18(14):3901-11. PubMed ID: 22586300 [TBL] [Abstract][Full Text] [Related]
9. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Yakes FM; Chinratanalab W; Ritter CA; King W; Seelig S; Arteaga CL Cancer Res; 2002 Jul; 62(14):4132-41. PubMed ID: 12124352 [TBL] [Abstract][Full Text] [Related]
10. The PI3K inhibitor GDC-0941 combines with existing clinical regimens for superior activity in multiple myeloma. Munugalavadla V; Mariathasan S; Slaga D; Du C; Berry L; Del Rosario G; Yan Y; Boe M; Sun L; Friedman LS; Chesi M; Leif Bergsagel P; Ebens A Oncogene; 2014 Jan; 33(3):316-25. PubMed ID: 23318440 [TBL] [Abstract][Full Text] [Related]
11. Targeting the PI3K/Akt/mTOR pathway with the pan-Akt inhibitor GDC-0068 in PIK3CA-mutant breast cancer brain metastases. Ippen FM; Grosch JK; Subramanian M; Kuter BM; Liederer BM; Plise EG; Mora JL; Nayyar N; Schmidt SP; Giobbie-Hurder A; Martinez-Lage M; Carter SL; Cahill DP; Wakimoto H; Brastianos PK Neuro Oncol; 2019 Nov; 21(11):1401-1411. PubMed ID: 31173106 [TBL] [Abstract][Full Text] [Related]
12. [Growth inhibition of combined pathway inhibitors on KRAS mutated non-small cell lung cancer cell line]. Li ZW; Yang ZL; Feng HL; Bian XC; Liu YY; Liu YQ Zhonghua Bing Li Xue Za Zhi; 2013 May; 42(5):330-5. PubMed ID: 24004591 [TBL] [Abstract][Full Text] [Related]
13. The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor. Tzeng HE; Yang L; Chen K; Wang Y; Liu YR; Pan SL; Gaur S; Hu S; Yen Y Oncotarget; 2015 May; 6(13):11061-73. PubMed ID: 25857298 [TBL] [Abstract][Full Text] [Related]
14. Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models. Spoerke JM; O'Brien C; Huw L; Koeppen H; Fridlyand J; Brachmann RK; Haverty PM; Pandita A; Mohan S; Sampath D; Friedman LS; Ross L; Hampton GM; Amler LC; Shames DS; Lackner MR Clin Cancer Res; 2012 Dec; 18(24):6771-83. PubMed ID: 23136191 [TBL] [Abstract][Full Text] [Related]
15. Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2). English DP; Bellone S; Cocco E; Bortolomai I; Pecorelli S; Lopez S; Silasi DA; Schwartz PE; Rutherford T; Santin AD Am J Obstet Gynecol; 2013 Nov; 209(5):465.e1-9. PubMed ID: 23891627 [TBL] [Abstract][Full Text] [Related]
16. The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in Ippen FM; Alvarez-Breckenridge CA; Kuter BM; Fink AL; Bihun IV; Lastrapes M; Penson T; Schmidt SP; Wojtkiewicz GR; Ning J; Subramanian M; Giobbie-Hurder A; Martinez-Lage M; Carter SL; Cahill DP; Wakimoto H; Brastianos PK Clin Cancer Res; 2019 Jun; 25(11):3374-3383. PubMed ID: 30796030 [TBL] [Abstract][Full Text] [Related]
17. Ellagic Acid Enhances the Efficacy of PI3K Inhibitor GDC-0941 in Breast Cancer Cells. Shi L; Gao X; Li X; Jiang N; Luo F; Gu C; Chen M; Cheng H; Liu P Curr Mol Med; 2015; 15(5):478-86. PubMed ID: 25941816 [TBL] [Abstract][Full Text] [Related]
18. Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer. Poovassery JS; Kang JC; Kim D; Ober RJ; Ward ES Int J Cancer; 2015 Jul; 137(2):267-77. PubMed ID: 25471734 [TBL] [Abstract][Full Text] [Related]
19. PIKing the right patient. Turke AB; Engelman JA Clin Cancer Res; 2010 Jul; 16(14):3523-5. PubMed ID: 20538763 [TBL] [Abstract][Full Text] [Related]
20. The novel dual PI3K/mTOR inhibitor GDC-0941 synergizes with the MEK inhibitor U0126 in non-small cell lung cancer cells. Zou ZQ; Zhang LN; Wang F; Bellenger J; Shen YZ; Zhang XH Mol Med Rep; 2012 Feb; 5(2):503-8. PubMed ID: 22101421 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]