322 related articles for article (PubMed ID: 24606918)
1. SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells.
Keller KE; Doctor ZM; Dwyer ZW; Lee YS
Mol Cell; 2014 Mar; 53(5):700-9. PubMed ID: 24606918
[TBL] [Abstract][Full Text] [Related]
2. Please keep me 2uned to PKM2.
McKnight SL
Mol Cell; 2014 Mar; 53(5):683-4. PubMed ID: 24606916
[TBL] [Abstract][Full Text] [Related]
3. SAICAR binding activates PKM2 protein kinase activity.
Cancer Discov; 2014 May; 4(5):OF20. PubMed ID: 24795025
[TBL] [Abstract][Full Text] [Related]
4. Succinyl-5-aminoimidazole-4-carboxamide-1-ribose 5'-Phosphate (SAICAR) Activates Pyruvate Kinase Isoform M2 (PKM2) in Its Dimeric Form.
Yan M; Chakravarthy S; Tokuda JM; Pollack L; Bowman GD; Lee YS
Biochemistry; 2016 Aug; 55(33):4731-6. PubMed ID: 27481063
[TBL] [Abstract][Full Text] [Related]
5. Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells.
Zhou Z; Li M; Zhang L; Zhao H; Şahin Ö; Chen J; Zhao JJ; Songyang Z; Yu D
Cancer Res; 2018 May; 78(9):2248-2261. PubMed ID: 29440169
[TBL] [Abstract][Full Text] [Related]
6. ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect.
Yang W; Zheng Y; Xia Y; Ji H; Chen X; Guo F; Lyssiotis CA; Aldape K; Cantley LC; Lu Z
Nat Cell Biol; 2012 Dec; 14(12):1295-304. PubMed ID: 23178880
[TBL] [Abstract][Full Text] [Related]
7. SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions.
Keller KE; Tan IS; Lee YS
Science; 2012 Nov; 338(6110):1069-72. PubMed ID: 23086999
[TBL] [Abstract][Full Text] [Related]
8. JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism.
Wang HJ; Hsieh YJ; Cheng WC; Lin CP; Lin YS; Yang SF; Chen CC; Izumiya Y; Yu JS; Kung HJ; Wang WC
Proc Natl Acad Sci U S A; 2014 Jan; 111(1):279-84. PubMed ID: 24344305
[TBL] [Abstract][Full Text] [Related]
9. Lack of Evidence for PKM2 Protein Kinase Activity.
Hosios AM; Fiske BP; Gui DY; Vander Heiden MG
Mol Cell; 2015 Sep; 59(5):850-7. PubMed ID: 26300261
[TBL] [Abstract][Full Text] [Related]
10. PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.
Jiang Y; Wang Y; Wang T; Hawke DH; Zheng Y; Li X; Zhou Q; Majumder S; Bi E; Liu DX; Huang S; Lu Z
Nat Commun; 2014 Nov; 5():5566. PubMed ID: 25412762
[TBL] [Abstract][Full Text] [Related]
11. Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23.
Wei Y; Wang D; Jin F; Bian Z; Li L; Liang H; Li M; Shi L; Pan C; Zhu D; Chen X; Hu G; Liu Y; Zhang CY; Zen K
Nat Commun; 2017 Jan; 8():14041. PubMed ID: 28067230
[TBL] [Abstract][Full Text] [Related]
12. PKM2 gene regulates the behavior of pancreatic cancer cells via mitogen-activated protein kinase pathways.
Feng J; Ma T; Ge Z; Lin J; Ding W; Chen H; Zhu W; Zhou S; Tan Y
Mol Med Rep; 2015 Mar; 11(3):2111-7. PubMed ID: 25411978
[TBL] [Abstract][Full Text] [Related]
13. Pyrimidine tract-binding protein 1 mediates pyruvate kinase M2-dependent phosphorylation of signal transducer and activator of transcription 3 and oncogenesis in anaplastic large cell lymphoma.
Hwang SR; Murga-Zamalloa C; Brown N; Basappa J; McDonnell SR; Mendoza-Reinoso V; Basrur V; Wilcox R; Elenitoba-Johnson K; Lim MS
Lab Invest; 2017 Aug; 97(8):962-970. PubMed ID: 28414323
[TBL] [Abstract][Full Text] [Related]
14. Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species.
Yokoyama M; Tanuma N; Shibuya R; Shiroki T; Abue M; Yamamoto K; Miura K; Yamaguchi K; Sato I; Tamai K; Satoh K
Int J Oncol; 2018 Mar; 52(3):881-891. PubMed ID: 29393401
[TBL] [Abstract][Full Text] [Related]
15. Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma.
Zhao X; Zhao L; Yang H; Li J; Min X; Yang F; Liu J; Huang G
J Biol Chem; 2018 Apr; 293(17):6623-6634. PubMed ID: 29514980
[TBL] [Abstract][Full Text] [Related]
16. PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.
Yang W; Xia Y; Hawke D; Li X; Liang J; Xing D; Aldape K; Hunter T; Alfred Yung WK; Lu Z
Cell; 2012 Aug; 150(4):685-96. PubMed ID: 22901803
[TBL] [Abstract][Full Text] [Related]
17. PKM2 Thr454 phosphorylation increases its nuclear translocation and promotes xenograft tumor growth in A549 human lung cancer cells.
Yu Z; Huang L; Qiao P; Jiang A; Wang L; Yang T; Tang S; Zhang W; Ren C
Biochem Biophys Res Commun; 2016 May; 473(4):953-958. PubMed ID: 27045080
[TBL] [Abstract][Full Text] [Related]
18. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
Xu Q; Tu J; Dou C; Zhang J; Yang L; Liu X; Lei K; Liu Z; Wang Y; Li L; Bao H; Wang J; Tu K
Mol Cancer; 2017 Dec; 16(1):178. PubMed ID: 29262861
[TBL] [Abstract][Full Text] [Related]
19. PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation.
Azoitei N; Becher A; Steinestel K; Rouhi A; Diepold K; Genze F; Simmet T; Seufferlein T
Mol Cancer; 2016 Jan; 15():3. PubMed ID: 26739387
[TBL] [Abstract][Full Text] [Related]
20. HDAC8-dependent deacetylation of PKM2 directs nuclear localization and glycolysis to promote proliferation in hepatocellular carcinoma.
Zhang R; Shen M; Wu C; Chen Y; Lu J; Li J; Zhao L; Meng H; Zhou X; Huang G; Zhao X; Liu J
Cell Death Dis; 2020 Dec; 11(12):1036. PubMed ID: 33279948
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
