229 related articles for article (PubMed ID: 24611490)
1. A new role for the nonpathogenic nonsynonymous single-nucleotide polymorphisms of acetylcholinesterase in the treatment of Alzheimer's disease: a computational study.
Saravanaraman P; Chinnadurai RK; Boopathy R
J Comput Biol; 2014 Aug; 21(8):632-47. PubMed ID: 24611490
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and evaluation of 7H-thiazolo-[3,2-b]-1,2,4-triazin-7-one derivatives as dual binding site acetylcholinesterase inhibitors.
Liu S; Shang R; Shi L; Zhou R; He J; Wan DC
Chem Biol Drug Des; 2014 Aug; 84(2):169-74. PubMed ID: 24890706
[TBL] [Abstract][Full Text] [Related]
3. Combined 3D-QSAR, molecular docking, and molecular dynamics study of tacrine derivatives as potential acetylcholinesterase (AChE) inhibitors of Alzheimer's disease.
Zhou A; Hu J; Wang L; Zhong G; Pan J; Wu Z; Hui A
J Mol Model; 2015 Oct; 21(10):277. PubMed ID: 26438408
[TBL] [Abstract][Full Text] [Related]
4. Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer's Disease.
Son M; Park C; Rampogu S; Zeb A; Lee KW
Int J Mol Sci; 2019 Feb; 20(4):. PubMed ID: 30823604
[TBL] [Abstract][Full Text] [Related]
5. Revealing the mechanistic pathway of cholinergic inhibition of Alzheimer's disease by donepezil: a metadynamics simulation study.
Ghosh S; Jana K; Ganguly B
Phys Chem Chem Phys; 2019 Jul; 21(25):13578-13589. PubMed ID: 31173012
[TBL] [Abstract][Full Text] [Related]
6. Cooperative hydrogen bonds and mobility of the non-aromatic ring as selectivity determinants for human acetylcholinesterase to similar anti-Alzheimer's galantaminics: a computational study.
Rocha REO; Lima LHF
J Biomol Struct Dyn; 2019 Apr; 37(7):1843-1856. PubMed ID: 29697300
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease.
Hamulakova S; Janovec L; Hrabinova M; Kristian P; Kuca K; Banasova M; Imrich J
Eur J Med Chem; 2012 Sep; 55():23-31. PubMed ID: 22818849
[TBL] [Abstract][Full Text] [Related]
8. Computational approach to suggest a new multi-target-directed ligand as a potential medication for Alzheimer's disease.
Eslami M; Nezafat N; Negahdaripour M; Ghasemi Y
J Biomol Struct Dyn; 2019 Nov; 37(18):4825-4839. PubMed ID: 30689517
[TBL] [Abstract][Full Text] [Related]
9. Identification of molecular descriptors for design of novel Isoalloxazine derivatives as potential Acetylcholinesterase inhibitors against Alzheimer's disease.
Gurung AB; Aguan K; Mitra S; Bhattacharjee A
J Biomol Struct Dyn; 2017 Jun; 35(8):1729-1742. PubMed ID: 27410776
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
[TBL] [Abstract][Full Text] [Related]
11. Oxime-dipeptides as anticholinesterase, reactivator of phosphonylated-serine of AChE catalytic triad: probing the mechanistic insight by MM-GBSA, dynamics simulations and DFT analysis.
Chadha N; Tiwari AK; Kumar V; Lal S; Milton MD; Mishra AK
J Biomol Struct Dyn; 2015; 33(5):978-90. PubMed ID: 24805972
[TBL] [Abstract][Full Text] [Related]
12. Use of ligand-based pharmacophore modeling and docking approach to find novel acetylcholinesterase inhibitors for treating Alzheimer's.
Dhanjal JK; Sharma S; Grover A; Das A
Biomed Pharmacother; 2015 Apr; 71():146-52. PubMed ID: 25960230
[TBL] [Abstract][Full Text] [Related]
13. Potential acetylcholinesterase inhibitors: molecular docking, molecular dynamics, and in silico prediction.
Kiametis AS; Silva MA; Romeiro LA; Martins JB; Gargano R
J Mol Model; 2017 Feb; 23(2):67. PubMed ID: 28185116
[TBL] [Abstract][Full Text] [Related]
14. Combining in silico and in vitro approaches to evaluate the acetylcholinesterase inhibitory profile of some commercially available flavonoids in the management of Alzheimer's disease.
Kuppusamy A; Arumugam M; George S
Int J Biol Macromol; 2017 Feb; 95():199-203. PubMed ID: 27871793
[TBL] [Abstract][Full Text] [Related]
15. In silico analyses of acetylcholinesterase (AChE) and its genetic variants in interaction with the anti-Alzheimer drug Rivastigmine.
Pereira GRC; Gonçalves LM; Abrahim-Vieira BA; De Mesquita JF
J Cell Biochem; 2022 Jul; 123(7):1259-1277. PubMed ID: 35644025
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease.
Li RS; Wang XB; Hu XJ; Kong LY
Bioorg Med Chem Lett; 2013 May; 23(9):2636-41. PubMed ID: 23511019
[TBL] [Abstract][Full Text] [Related]
17. Discovery of potential inhibitor against human acetylcholinesterase: a molecular docking and molecular dynamics investigation.
Singh SP; Gupta D
Comput Biol Chem; 2017 Jun; 68():224-230. PubMed ID: 28432980
[TBL] [Abstract][Full Text] [Related]
18. Novel tacrine analogs as potential cholinesterase inhibitors in Alzheimer's disease.
El-Malah A; Gedawy EM; Kassab AE; Salam RM
Arch Pharm (Weinheim); 2014 Feb; 347(2):96-103. PubMed ID: 24343873
[TBL] [Abstract][Full Text] [Related]
19. Quantifying ligand-receptor interactions for gorge-spanning acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
Martis EA; Chandarana RC; Shaikh MS; Ambre PK; D'Souza JS; Iyer KR; Coutinho EC; Nandan SR; Pissurlenkar RR
J Biomol Struct Dyn; 2015; 33(5):1107-25. PubMed ID: 24905476
[TBL] [Abstract][Full Text] [Related]
20. Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates.
Camps P; Formosa X; Galdeano C; Gómez T; Muñoz-Torrero D; Ramírez L; Viayna E; Gómez E; Isambert N; Lavilla R; Badia A; Clos MV; Bartolini M; Mancini F; Andrisano V; Bidon-Chanal A; Huertas O; Dafni T; Luque FJ
Chem Biol Interact; 2010 Sep; 187(1-3):411-5. PubMed ID: 20167211
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
