These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

326 related articles for article (PubMed ID: 24612393)

  • 1. Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.
    Moore SF; Hunter RW; Hers I
    J Thromb Haemost; 2014 May; 12(5):748-60. PubMed ID: 24612393
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.
    Miyazaki M; McCarthy JJ; Fedele MJ; Esser KA
    J Physiol; 2011 Apr; 589(Pt 7):1831-46. PubMed ID: 21300751
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
    Misra UK; Pizzo SV
    PLoS One; 2012; 7(12):e51735. PubMed ID: 23272152
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alkaline intracellular pH (pHi) increases PI3K activity to promote mTORC1 and mTORC2 signaling and function during growth factor limitation.
    Kazyken D; Lentz SI; Wadley M; Fingar DC
    J Biol Chem; 2023 Sep; 299(9):105097. PubMed ID: 37507012
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
    Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
    J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
    [TBL] [Abstract][Full Text] [Related]  

  • 7. AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation.
    Ning J; Clemmons DR
    Mol Endocrinol; 2010 Jun; 24(6):1218-29. PubMed ID: 20363874
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β.
    O'Brien KA; Gartner TK; Hay N; Du X
    Arterioscler Thromb Vasc Biol; 2012 Sep; 32(9):2232-40. PubMed ID: 22814751
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
    Copps KD; Hançer NJ; Qiu W; White MF
    J Biol Chem; 2016 Apr; 291(16):8602-17. PubMed ID: 26846849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ERK1/2-dependent activation of mTOR/mTORC1/p70S6K regulates thrombin-induced RPE cell proliferation.
    Parrales A; López E; Lee-Rivera I; López-Colomé AM
    Cell Signal; 2013 Apr; 25(4):829-38. PubMed ID: 23291002
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protease-activated receptor-induced Akt activation--regulation and possible function.
    Reséndiz JC; Kroll MH; Lassila R
    J Thromb Haemost; 2007 Dec; 5(12):2484-93. PubMed ID: 17883592
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage.
    Cam M; Bid HK; Xiao L; Zambetti GP; Houghton PJ; Cam H
    J Biol Chem; 2014 Feb; 289(7):4083-94. PubMed ID: 24366874
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin.
    Tee AR; Anjum R; Blenis J
    J Biol Chem; 2003 Sep; 278(39):37288-96. PubMed ID: 12867426
    [TBL] [Abstract][Full Text] [Related]  

  • 14. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
    Palaniappan M; Menon KM
    Mol Endocrinol; 2010 Sep; 24(9):1782-93. PubMed ID: 20660299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer.
    Yang F; Deng R; Qian XJ; Chang SH; Wu XQ; Qin J; Feng GK; Ding K; Zhu XF
    Cell Death Dis; 2014 Mar; 5(3):e1114. PubMed ID: 24625973
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes.
    Miyazaki M; McCarthy JJ; Esser KA
    FEBS J; 2010 May; 277(9):2180-91. PubMed ID: 20412061
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.
    Zhang HH; Huang J; Düvel K; Boback B; Wu S; Squillace RM; Wu CL; Manning BD
    PLoS One; 2009 Jul; 4(7):e6189. PubMed ID: 19593385
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway.
    Bommer UA; Iadevaia V; Chen J; Knoch B; Engel M; Proud CG
    Cell Signal; 2015 Aug; 27(8):1557-68. PubMed ID: 25936523
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets.
    Dangelmaier C; Kunapuli SP
    Platelets; 2022 Nov; 33(8):1301-1306. PubMed ID: 35514261
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.