73 related articles for article (PubMed ID: 24615350)
1. Proteomics and phosphoproteomics provide insights into the mechanism of action of a novel pyrazolo[3,4-d]pyrimidine Src inhibitor in human osteosarcoma.
Bernardini G; Laschi M; Serchi T; Spreafico A; Botta M; Schenone S; Arena S; Geminiani M; Scaloni A; Collodel G; Orlandini M; Niccolai N; Santucci A
Mol Biosyst; 2014 Jun; 10(6):1305-12. PubMed ID: 24615350
[TBL] [Abstract][Full Text] [Related]
2. Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells.
Spreafico A; Schenone S; Serchi T; Orlandini M; Angelucci A; Magrini D; Bernardini G; Collodel G; Di Stefano A; Tintori C; Bologna M; Manetti F; Botta M; Santucci A
FASEB J; 2008 May; 22(5):1560-71. PubMed ID: 18171692
[TBL] [Abstract][Full Text] [Related]
3. Differentially activated Src kinase in chemo-naïve human primary osteosarcoma cells and effects of a Src kinase inhibitor.
Laschi M; Bernardini G; Geminiani M; Manetti F; Mori M; Spreafico A; Campanacci D; Capanna R; Schenone S; Botta M; Santucci A
Biofactors; 2017 Nov; 43(6):801-811. PubMed ID: 28786551
[TBL] [Abstract][Full Text] [Related]
4. New pyrazolo[3,4-d]pyrimidine SRC inhibitors induce apoptosis in mesothelioma cell lines through p27 nuclear stabilization.
Indovina P; Giorgi F; Rizzo V; Khadang B; Schenone S; Di Marzo D; Forte IM; Tomei V; Mattioli E; D'Urso V; Grilli B; Botta M; Giordano A; Pentimalli F
Oncogene; 2012 Feb; 31(7):929-38. PubMed ID: 21785466
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo.
Hingorani P; Zhang W; Gorlick R; Kolb EA
Clin Cancer Res; 2009 May; 15(10):3416-22. PubMed ID: 19447875
[TBL] [Abstract][Full Text] [Related]
6. Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.
Carraro F; Naldini A; Pucci A; Locatelli GA; Maga G; Schenone S; Bruno O; Ranise A; Bondavalli F; Brullo C; Fossa P; Menozzi G; Mosti L; Modugno M; Tintori C; Manetti F; Botta M
J Med Chem; 2006 Mar; 49(5):1549-61. PubMed ID: 16509573
[TBL] [Abstract][Full Text] [Related]
7. Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival.
Shor AC; Keschman EA; Lee FY; Muro-Cacho C; Letson GD; Trent JC; Pledger WJ; Jove R
Cancer Res; 2007 Mar; 67(6):2800-8. PubMed ID: 17363602
[TBL] [Abstract][Full Text] [Related]
8. Lapatinib alters the malignant phenotype of osteosarcoma cells via downregulation of the activity of the HER2-PI3K/AKT-FASN axis in vitro.
Long XH; Zhang GM; Peng AF; Luo QF; Zhang L; Wen HC; Zhou RP; Gao S; Zhou Y; Liu ZL
Oncol Rep; 2014 Jan; 31(1):328-34. PubMed ID: 24172910
[TBL] [Abstract][Full Text] [Related]
9. Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice.
Manetti F; Santucci A; Locatelli GA; Maga G; Spreafico A; Serchi T; Orlandini M; Bernardini G; Caradonna NP; Spallarossa A; Brullo C; Schenone S; Bruno O; Ranise A; Bondavalli F; Hoffmann O; Bologna M; Angelucci A; Botta M
J Med Chem; 2007 Nov; 50(23):5579-88. PubMed ID: 17929792
[TBL] [Abstract][Full Text] [Related]
10. Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.
Carraro F; Pucci A; Naldini A; Schenone S; Bruno O; Ranise A; Bondavalli F; Brullo C; Fossa P; Menozzi G; Mosti L; Manetti F; Botta M
J Med Chem; 2004 Mar; 47(7):1595-8. PubMed ID: 15027847
[TBL] [Abstract][Full Text] [Related]
11. Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells.
Navarra M; Celano M; Maiuolo J; Schenone S; Botta M; Angelucci A; Bramanti P; Russo D
BMC Cancer; 2010 Nov; 10():602. PubMed ID: 21050441
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of nuclear factor-κB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells.
Castro-Gamero AM; Borges KS; da Silva Silveira V; Lira RC; de Paula Gomes Queiroz R; Valera FC; Scrideli CA; Umezawa K; Tone LG
Anticancer Drugs; 2012 Jul; 23(6):638-50. PubMed ID: 22382389
[TBL] [Abstract][Full Text] [Related]
13. Proteomics study of oxidative stress and Src kinase inhibition in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment.
Chou HC; Chen YW; Lee TR; Wu FS; Chan HT; Lyu PC; Timms JF; Chan HL
Free Radic Biol Med; 2010 Jul; 49(1):96-108. PubMed ID: 20385227
[TBL] [Abstract][Full Text] [Related]
14. New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation.
Schenone S; Bruno O; Ranise A; Bondavalli F; Brullo C; Fossa P; Mosti L; Menozzi G; Carraro F; Naldini A; Bernini C; Manetti F; Botta M
Bioorg Med Chem Lett; 2004 May; 14(10):2511-7. PubMed ID: 15109642
[TBL] [Abstract][Full Text] [Related]
15. Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells.
Angelucci A; Schenone S; Gravina GL; Muzi P; Festuccia C; Vicentini C; Botta M; Bologna M
Eur J Cancer; 2006 Nov; 42(16):2838-45. PubMed ID: 16973347
[TBL] [Abstract][Full Text] [Related]
16. 2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.
Dreassi E; Zizzari AT; Mori M; Filippi I; Belfiore A; Naldini A; Carraro F; Santucci A; Schenone S; Botta M
Eur J Med Chem; 2010 Dec; 45(12):5958-64. PubMed ID: 20970221
[TBL] [Abstract][Full Text] [Related]
17. Cytoprotective role of autophagy during paclitaxel-induced apoptosis in Saos-2 osteosarcoma cells.
Kim HJ; Lee SG; Kim YJ; Park JE; Lee KY; Yoo YH; Kim JM
Int J Oncol; 2013 Jun; 42(6):1985-92. PubMed ID: 23563171
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.
Radi M; Dreassi E; Brullo C; Crespan E; Tintori C; Bernardo V; Valoti M; Zamperini C; Daigl H; Musumeci F; Carraro F; Naldini A; Filippi I; Maga G; Schenone S; Botta M
J Med Chem; 2011 Apr; 54(8):2610-26. PubMed ID: 21443205
[TBL] [Abstract][Full Text] [Related]
19. Tanshinone IIA induces apoptosis and inhibits the proliferation, migration, and invasion of the osteosarcoma MG-63 cell line in vitro.
Zhang Y; Wei RX; Zhu XB; Cai L; Jin W; Hu H
Anticancer Drugs; 2012 Feb; 23(2):212-9. PubMed ID: 22126901
[TBL] [Abstract][Full Text] [Related]
20. [Proteomics research of bufalin-induced apoptosis in osteosarcoma cell lines].
Xie XB; Wen LL; Yin JQ; Liao HY; Zou CY; Wang B; Huang G; Shen JN
Zhongguo Zhong Yao Za Zhi; 2014 Jul; 39(14):2739-43. PubMed ID: 25272506
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
