BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 24619300)

  • 1. "Targeting Taspase1 for Cancer Therapy"-Response.
    Chen DY; Takeda S; Oyama T; Hsieh JJ
    Cancer Res; 2012 Jun; 72(11):2913. PubMed ID: 24619300
    [No Abstract]   [Full Text] [Related]  

  • 2. Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis.
    Chen DY; Liu H; Takeda S; Tu HC; Sasagawa S; Van Tine BA; Lu D; Cheng EH; Hsieh JJ
    Cancer Res; 2010 Jul; 70(13):5358-67. PubMed ID: 20516119
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Taspase1: a 'misunderstood' protease with translational cancer relevance.
    Wünsch D; Hahlbrock A; Jung S; Schirmeister T; van den Boom J; Schilling O; Knauer SK; Stauber RH
    Oncogene; 2016 Jun; 35(26):3351-64. PubMed ID: 26657154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of the catalytically impaired Taspase1 T234V or Taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cells.
    Bier C; Hecht R; Kunst L; Scheiding S; Wünsch D; Goesswein D; Schneider G; Krämer OH; Knauer SK; Stauber RH
    PLoS One; 2012; 7(5):e34142. PubMed ID: 22570686
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A pharmacologic inhibitor of the protease Taspase1 effectively inhibits breast and brain tumor growth.
    Chen DY; Lee Y; Van Tine BA; Searleman AC; Westergard TD; Liu H; Tu HC; Takeda S; Dong Y; Piwnica-Worms DR; Oh KJ; Korsmeyer SJ; Hermone A; Gussio R; Shoemaker RH; Cheng EH; Hsieh JJ
    Cancer Res; 2012 Feb; 72(3):736-46. PubMed ID: 22166309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivo.
    Bier C; Knauer SK; Wünsch D; Kunst L; Scheiding S; Kaiser M; Ottmann C; Krämer OH; Stauber RH
    FASEB J; 2012 Aug; 26(8):3421-9. PubMed ID: 22623586
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.
    Takeda S; Chen DY; Westergard TD; Fisher JK; Rubens JA; Sasagawa S; Kan JT; Korsmeyer SJ; Cheng EH; Hsieh JJ
    Genes Dev; 2006 Sep; 20(17):2397-409. PubMed ID: 16951254
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia.
    Zhao Z; Wang L; Volk AG; Birch NW; Stoltz KL; Bartom ET; Marshall SA; Rendleman EJ; Nestler CM; Shilati J; Schiltz GE; Crispino JD; Shilatifard A
    Genes Dev; 2019 Jan; 33(1-2):61-74. PubMed ID: 30573454
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID.
    Malecová B; Caputo VS; Lee DF; Hsieh JJ; Oelgeschläger T
    Transcription; 2015; 6(2):21-32. PubMed ID: 25996597
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bioassays to monitor Taspase1 function for the identification of pharmacogenetic inhibitors.
    Knauer SK; Fetz V; Rabenstein J; Friedl S; Hofmann B; Sabiani S; Schröder E; Kunst L; Proschak E; Thines E; Kindler T; Schneider G; Marschalek R; Stauber RH; Bier C
    PLoS One; 2011; 6(5):e18253. PubMed ID: 21647428
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The importin-alpha/nucleophosmin switch controls taspase1 protease function.
    Bier C; Knauer SK; Docter D; Schneider G; Krämer OH; Stauber RH
    Traffic; 2011 Jun; 12(6):703-14. PubMed ID: 21418451
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell-based analysis of structure-function activity of threonine aspartase 1.
    Bier C; Knauer SK; Klapthor A; Schweitzer A; Rekik A; Krämer OH; Marschalek R; Stauber RH
    J Biol Chem; 2011 Jan; 286(4):3007-17. PubMed ID: 21084304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein.
    Sabiani S; Geppert T; Engelbrecht C; Kowarz E; Schneider G; Marschalek R
    EBioMedicine; 2015 May; 2(5):386-95. PubMed ID: 26137584
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, syntheses, and evaluation of Taspase1 inhibitors.
    Lee JT; Chen DY; Yang Z; Ramos AD; Hsieh JJ; Bogyo M
    Bioorg Med Chem Lett; 2009 Sep; 19(17):5086-90. PubMed ID: 19631530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression.
    Hsieh JJ; Cheng EH; Korsmeyer SJ
    Cell; 2003 Oct; 115(3):293-303. PubMed ID: 14636557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.
    Oyama T; Sasagawa S; Takeda S; Hess RA; Lieberman PM; Cheng EH; Hsieh JJ
    Dev Cell; 2013 Oct; 27(2):188-200. PubMed ID: 24176642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fly versus man: evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's Taspase1.
    Wünsch D; Hahlbrock A; Heiselmayer C; Bäcker S; Heun P; Goesswein D; Stöcker W; Schirmeister T; Schneider G; Krämer OH; Knauer SK; Stauber RH
    FASEB J; 2015 May; 29(5):1973-85. PubMed ID: 25634959
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting Taspase1 for cancer therapy--letter.
    Stauber RH; Bier C; Knauer SK
    Cancer Res; 2012 Jun; 72(11):2912; author reply 2913. PubMed ID: 22593195
    [No Abstract]   [Full Text] [Related]  

  • 19. PEGylated sequence-controlled macromolecules using supramolecular binding to target the Taspase1/Importin α interaction.
    Pasch P; Höing A; Ueclue S; Killa M; Voskuhl J; Knauer SK; Hartmann L
    Chem Commun (Camb); 2021 Mar; 57(25):3091-3094. PubMed ID: 33625405
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The other side of the corona: nanoparticles inhibit the protease taspase1 in a size-dependent manner.
    van den Boom J; Hensel A; Trusch F; Matena A; Siemer S; Guel D; Docter D; Höing A; Bayer P; Stauber RH; Knauer SK
    Nanoscale; 2020 Oct; 12(37):19093-19103. PubMed ID: 32662484
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.