357 related articles for article (PubMed ID: 24623279)
1. Re-trafficking of hERG reverses long QT syndrome 2 phenotype in human iPS-derived cardiomyocytes.
Mehta A; Sequiera GL; Ramachandra CJ; Sudibyo Y; Chung Y; Sheng J; Wong KY; Tan TH; Wong P; Liew R; Shim W
Cardiovasc Res; 2014 Jun; 102(3):497-506. PubMed ID: 24623279
[TBL] [Abstract][Full Text] [Related]
2. The KCNH2-IVS9-28A/G mutation causes aberrant isoform expression and hERG trafficking defect in cardiomyocytes derived from patients affected by Long QT Syndrome type 2.
Mura M; Mehta A; Ramachandra CJ; Zappatore R; Pisano F; Ciuffreda MC; Barbaccia V; Crotti L; Schwartz PJ; Shim W; Gnecchi M
Int J Cardiol; 2017 Aug; 240():367-371. PubMed ID: 28433559
[TBL] [Abstract][Full Text] [Related]
3. Intracellular Mechanism of Rosuvastatin-Induced Decrease in Mature hERG Protein Expression on Membrane.
Feng PF; Zhang B; Zhao L; Fang Q; Liu Y; Wang JN; Xu XQ; Xue H; Li Y; Yan CC; Zhao X; Li BX
Mol Pharm; 2019 Apr; 16(4):1477-1488. PubMed ID: 30807184
[TBL] [Abstract][Full Text] [Related]
4. Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome.
Jouni M; Si-Tayeb K; Es-Salah-Lamoureux Z; Latypova X; Champon B; Caillaud A; Rungoat A; Charpentier F; Loussouarn G; Baró I; Zibara K; Lemarchand P; Gaborit N
J Am Heart Assoc; 2015 Sep; 4(9):e002159. PubMed ID: 26330336
[TBL] [Abstract][Full Text] [Related]
5. Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Liu QN; Trudeau MC
PLoS One; 2015; 10(4):e0123951. PubMed ID: 25923442
[TBL] [Abstract][Full Text] [Related]
6. Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Duncan G; Firth K; George V; Hoang MD; Staniforth A; Smith G; Denning C
Stem Cells Dev; 2017 Dec; 26(23):1695-1705. PubMed ID: 28992755
[TBL] [Abstract][Full Text] [Related]
7. Tbx20 controls the expression of the KCNH2 gene and of hERG channels.
Caballero R; Utrilla RG; Amorós I; Matamoros M; Pérez-Hernández M; Tinaquero D; Alfayate S; Nieto-Marín P; Guerrero-Serna G; Liu QH; Ramos-Mondragón R; Ponce-Balbuena D; Herron T; Campbell KF; Filgueiras-Rama D; Peinado R; López-Sendón JL; Jalife J; Delpón E; Tamargo J
Proc Natl Acad Sci U S A; 2017 Jan; 114(3):E416-E425. PubMed ID: 28049825
[TBL] [Abstract][Full Text] [Related]
8. Promise and Potential Peril With Lumacaftor for the Trafficking Defective Type 2 Long-QT Syndrome-Causative Variants, p.G604S, p.N633S, and p.R685P, Using Patient-Specific Re-Engineered Cardiomyocytes.
O'Hare BJ; John Kim CS; Hamrick SK; Ye D; Tester DJ; Ackerman MJ
Circ Genom Precis Med; 2020 Oct; 13(5):466-475. PubMed ID: 32940533
[TBL] [Abstract][Full Text] [Related]
9. The role and mechanism of chaperones Calnexin/Calreticulin in which ALLN selectively rescues the trafficking defective of HERG-A561V mutation.
Wang Y; Shen T; Fang P; Zhou J; Lou K; Cen Z; Qian H; Zhou J; Liu N; Lian J
Biosci Rep; 2018 Oct; 38(5):. PubMed ID: 29752336
[TBL] [Abstract][Full Text] [Related]
10. R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome.
Mesquita FCP; Arantes PC; Kasai-Brunswick TH; Araujo DS; Gubert F; Monnerat G; Silva Dos Santos D; Neiman G; Leitão IC; Barbosa RAQ; Coutinho JL; Vaz IM; Dos Santos MN; Borgonovo T; Cruz FES; Miriuka S; Medei EH; Campos de Carvalho AC; Carvalho AB
Sci Rep; 2019 Dec; 9(1):19203. PubMed ID: 31844156
[TBL] [Abstract][Full Text] [Related]
11. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function.
Lin EC; Moungey BM; Lim E; Concannon SP; Anderson CL; Kyle JW; Makielski JC; Balijepalli SY; January CT
J Am Heart Assoc; 2014 Dec; 3(6):e001491. PubMed ID: 25497881
[TBL] [Abstract][Full Text] [Related]
12. HERG trafficking and pharmacological rescue of LQTS-2 mutant channels.
Robertson GA; January CT
Handb Exp Pharmacol; 2006; (171):349-55. PubMed ID: 16610352
[TBL] [Abstract][Full Text] [Related]
13. Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.
Perrin MJ; Subbiah RN; Vandenberg JI; Hill AP
Prog Biophys Mol Biol; 2008; 98(2-3):137-48. PubMed ID: 19027781
[TBL] [Abstract][Full Text] [Related]
14. Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells.
Jehle J; Ficker E; Wan X; Deschenes I; Kisselbach J; Wiedmann F; Staudacher I; Schmidt C; Schweizer PA; Becker R; Katus HA; Thomas D
Br J Pharmacol; 2013 Mar; 168(5):1215-29. PubMed ID: 23061993
[TBL] [Abstract][Full Text] [Related]
15. Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model.
Mehta A; Ramachandra CJA; Singh P; Chitre A; Lua CH; Mura M; Crotti L; Wong P; Schwartz PJ; Gnecchi M; Shim W
Eur Heart J; 2018 Apr; 39(16):1446-1455. PubMed ID: 29020304
[TBL] [Abstract][Full Text] [Related]
16. hERG 1b is critical for human cardiac repolarization.
Jones DK; Liu F; Vaidyanathan R; Eckhardt LL; Trudeau MC; Robertson GA
Proc Natl Acad Sci U S A; 2014 Dec; 111(50):18073-7. PubMed ID: 25453103
[TBL] [Abstract][Full Text] [Related]
17. Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.
Bellin M; Casini S; Davis RP; D'Aniello C; Haas J; Ward-van Oostwaard D; Tertoolen LG; Jung CB; Elliott DA; Welling A; Laugwitz KL; Moretti A; Mummery CL
EMBO J; 2013 Dec; 32(24):3161-75. PubMed ID: 24213244
[TBL] [Abstract][Full Text] [Related]
18. Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes.
Matsa E; Dixon JE; Medway C; Georgiou O; Patel MJ; Morgan K; Kemp PJ; Staniforth A; Mellor I; Denning C
Eur Heart J; 2014 Apr; 35(16):1078-87. PubMed ID: 23470493
[TBL] [Abstract][Full Text] [Related]
19. Long QT syndrome-associated I593R mutation in HERG potassium channel activates ER stress pathways.
Keller SH; Platoshyn O; Yuan JX
Cell Biochem Biophys; 2005; 43(3):365-77. PubMed ID: 16244363
[TBL] [Abstract][Full Text] [Related]
20. Patient-Specific and Gene-Corrected Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Short QT Syndrome.
Guo F; Sun Y; Wang X; Wang H; Wang J; Gong T; Chen X; Zhang P; Su L; Fu G; Su J; Yang S; Lai R; Jiang C; Liang P
Circ Res; 2019 Jan; 124(1):66-78. PubMed ID: 30582453
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
