BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 24628236)

  • 1. Current view on the mechanism of action of perifosine in cancer.
    Fensterle J; Aicher B; Seipelt I; Teifel M; Engel J
    Anticancer Agents Med Chem; 2014 May; 14(4):629-35. PubMed ID: 24628236
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Perifosine: update on a novel Akt inhibitor.
    Gills JJ; Dennis PA
    Curr Oncol Rep; 2009 Mar; 11(2):102-10. PubMed ID: 19216841
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
    Chiarini F; Del Sole M; Mongiorgi S; Gaboardi GC; Cappellini A; Mantovani I; Follo MY; McCubrey JA; Martelli AM
    Leukemia; 2008 Jun; 22(6):1106-16. PubMed ID: 18385752
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anticancer mechanisms and clinical application of alkylphospholipids.
    van Blitterswijk WJ; Verheij M
    Biochim Biophys Acta; 2013 Mar; 1831(3):663-74. PubMed ID: 23137567
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
    Li Z; Tan F; Liewehr DJ; Steinberg SM; Thiele CJ
    J Natl Cancer Inst; 2010 Jun; 102(11):758-70. PubMed ID: 20463309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells.
    van der Luit AH; Vink SR; Klarenbeek JB; Perrissoud D; Solary E; Verheij M; van Blitterswijk WJ
    Mol Cancer Ther; 2007 Aug; 6(8):2337-45. PubMed ID: 17699729
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Perifosine synergistically enhances TRAIL-induced myeloma cell apoptosis via up-regulation of death receptors.
    David E; Sinha R; Chen J; Sun SY; Kaufman JL; Lonial S
    Clin Cancer Res; 2008 Aug; 14(16):5090-8. PubMed ID: 18698026
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Perifosine as a potential novel anti-cancer agent inhibits EGFR/MET-AKT axis in malignant pleural mesothelioma.
    Pinton G; Manente AG; Angeli G; Mutti L; Moro L
    PLoS One; 2012; 7(5):e36856. PubMed ID: 22590625
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preclinical evaluation of perifosine as a potential promising anti-rhabdomyosarcoma agent.
    Shen J; Hong Y; Zhao Q; Zhang JL
    Tumour Biol; 2016 Jan; 37(1):1025-33. PubMed ID: 26269112
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of programmed cell death by inhibition of AKT with the alkylphosphocholine perifosine in in vitro models of platinum sensitive and resistant ovarian cancers.
    Engel JB; Schönhals T; Häusler S; Krockenberger M; Schmidt M; Horn E; Köster F; Dietl J; Wischhusen J; Honig A
    Arch Gynecol Obstet; 2011 Mar; 283(3):603-10. PubMed ID: 20405296
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest.
    Al Sawah E; Chen X; Marchion DC; Xiong Y; Ramirez IJ; Abbasi F; Bou Zgheib N; Chon HS; Wenham RM; Apte SM; Judson PL; Lancaster JM
    Gynecol Oncol; 2013 Oct; 131(1):207-12. PubMed ID: 23877012
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
    Kumar A; Fillmore HL; Kadian R; Broaddus WC; Tye GW; Van Meter TE
    Mol Cancer Res; 2009 Nov; 7(11):1813-21. PubMed ID: 19887560
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.
    Engel JB; Honig A; Schönhals T; Weidler C; Häusler S; Krockenberger M; Grunewald TG; Dombrowski Y; Rieger L; Dietl J; Wischhusen J
    Eur J Obstet Gynecol Reprod Biol; 2008 Nov; 141(1):64-9. PubMed ID: 18687514
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
    Papa V; Tazzari PL; Chiarini F; Cappellini A; Ricci F; Billi AM; Evangelisti C; Ottaviani E; Martinelli G; Testoni N; McCubrey JA; Martelli AM
    Leukemia; 2008 Jan; 22(1):147-60. PubMed ID: 17928881
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.
    Reis-Sobreiro M; Gajate C; Mollinedo F
    Oncogene; 2009 Sep; 28(36):3221-34. PubMed ID: 19561642
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary.
    Sasano T; Mabuchi S; Kuroda H; Kawano M; Matsumoto Y; Takahashi R; Hisamatsu T; Sawada K; Hashimoto K; Isobe A; Testa JR; Kimura T
    Mol Cancer Res; 2015 Apr; 13(4):795-806. PubMed ID: 25519148
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M; Reese E; Dai Y; Bauer C; Payne SG; Dent P; Spiegel S; Grant S
    Cancer Res; 2005 Mar; 65(6):2422-32. PubMed ID: 15781658
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells.
    Li X; Luwor R; Lu Y; Liang K; Fan Z
    Oncogene; 2006 Jan; 25(4):525-35. PubMed ID: 16170346
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Perifosine induces cell apoptosis in human osteosarcoma cells: new implication for osteosarcoma therapy?
    Yao C; Wei JJ; Wang ZY; Ding HM; Li D; Yan SC; Yang YJ; Gu ZP
    Cell Biochem Biophys; 2013 Mar; 65(2):217-27. PubMed ID: 23015227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines.
    Dasmahapatra GP; Didolkar P; Alley MC; Ghosh S; Sausville EA; Roy KK
    Clin Cancer Res; 2004 Aug; 10(15):5242-52. PubMed ID: 15297428
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.