225 related articles for article (PubMed ID: 24632501)
1. Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues.
Heuzé Y; Singh N; Basilico C; Jabs EW; Holmes G; Richtsmeier JT
Bone; 2014 Jun; 63():101-9. PubMed ID: 24632501
[TBL] [Abstract][Full Text] [Related]
2. Mesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome.
Holmes G; Basilico C
Dev Biol; 2012 Aug; 368(2):283-93. PubMed ID: 22664175
[TBL] [Abstract][Full Text] [Related]
3. A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.
Yin L; Du X; Li C; Xu X; Chen Z; Su N; Zhao L; Qi H; Li F; Xue J; Yang J; Jin M; Deng C; Chen L
Bone; 2008 Apr; 42(4):631-43. PubMed ID: 18242159
[TBL] [Abstract][Full Text] [Related]
4. Beyond the closed suture in apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth.
Martínez-Abadías N; Percival C; Aldridge K; Hill CA; Ryan T; Sirivunnabood S; Wang Y; Jabs EW; Richtsmeier JT
Dev Dyn; 2010 Nov; 239(11):3058-71. PubMed ID: 20842696
[TBL] [Abstract][Full Text] [Related]
5. Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.
Wang Y; Sun M; Uhlhorn VL; Zhou X; Peter I; Martinez-Abadias N; Hill CA; Percival CJ; Richtsmeier JT; Huso DL; Jabs EW
BMC Dev Biol; 2010 Feb; 10():22. PubMed ID: 20175913
[TBL] [Abstract][Full Text] [Related]
6. Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant mice.
Motch Perrine SM; Cole TM; Martínez-Abadías N; Aldridge K; Jabs EW; Richtsmeier JT
BMC Dev Biol; 2014 Feb; 14():8. PubMed ID: 24580805
[TBL] [Abstract][Full Text] [Related]
7. The study of abnormal bone development in the Apert syndrome Fgfr2+/S252W mouse using a 3D hydrogel culture model.
Yang F; Wang Y; Zhang Z; Hsu B; Jabs EW; Elisseeff JH
Bone; 2008 Jul; 43(1):55-63. PubMed ID: 18407821
[TBL] [Abstract][Full Text] [Related]
8. Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model.
Morita J; Nakamura M; Kobayashi Y; Deng CX; Funato N; Moriyama K
Dev Dyn; 2014 Apr; 243(4):560-7. PubMed ID: 24259495
[TBL] [Abstract][Full Text] [Related]
9. Further analysis of the Crouzon mouse: effects of the FGFR2(C342Y) mutation are cranial bone-dependent.
Liu J; Nam HK; Wang E; Hatch NE
Calcif Tissue Int; 2013 May; 92(5):451-66. PubMed ID: 23358860
[TBL] [Abstract][Full Text] [Related]
10. Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology.
Holmes G; Rothschild G; Roy UB; Deng CX; Mansukhani A; Basilico C
Dev Biol; 2009 Apr; 328(2):273-84. PubMed ID: 19389359
[TBL] [Abstract][Full Text] [Related]
11. The Fgfr2(S252W/+) mutation in mice retards mandible formation and reduces bone mass as in human Apert syndrome.
Zhou X; Pu D; Liu R; Li X; Wen X; Zhang L; Chen L; Deng M; Liu L
Am J Med Genet A; 2013 May; 161A(5):983-92. PubMed ID: 23495007
[TBL] [Abstract][Full Text] [Related]
12. Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome.
Yeh E; Fanganiello RD; Sunaga DY; Zhou X; Holmes G; Rocha KM; Alonso N; Matushita H; Wang Y; Jabs EW; Passos-Bueno MR
PLoS One; 2013; 8(4):e60439. PubMed ID: 23593218
[TBL] [Abstract][Full Text] [Related]
13. From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome.
Martínez-Abadías N; Holmes G; Pankratz T; Wang Y; Zhou X; Jabs EW; Richtsmeier JT
Dis Model Mech; 2013 May; 6(3):768-79. PubMed ID: 23519026
[TBL] [Abstract][Full Text] [Related]
14. Facial suture synostosis of newborn Fgfr1(P250R/+) and Fgfr2(S252W/+) mouse models of Pfeiffer and Apert syndromes.
Purushothaman R; Cox TC; Maga AM; Cunningham ML
Birth Defects Res A Clin Mol Teratol; 2011 Jul; 91(7):603-9. PubMed ID: 21538817
[TBL] [Abstract][Full Text] [Related]
15. Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis.
Yokota M; Kobayashi Y; Morita J; Suzuki H; Hashimoto Y; Sasaki Y; Akiyoshi K; Moriyama K
PLoS One; 2014; 9(7):e101693. PubMed ID: 25003957
[TBL] [Abstract][Full Text] [Related]
16. A Ser252Trp mutation in fibroblast growth factor receptor 2 (FGFR2) mimicking human Apert syndrome reveals an essential role for FGF signaling in the regulation of endochondral bone formation.
Chen P; Zhang L; Weng T; Zhang S; Sun S; Chang M; Li Y; Zhang B; Zhang L
PLoS One; 2014; 9(1):e87311. PubMed ID: 24489893
[TBL] [Abstract][Full Text] [Related]
17. Negative autoregulation of fibroblast growth factor receptor 2 expression characterizing cranial development in cases of Apert (P253R mutation) and Pfeiffer (C278F mutation) syndromes and suggesting a basis for differences in their cranial phenotypes.
Britto JA; Moore RL; Evans RD; Hayward RD; Jones BM
J Neurosurg; 2001 Oct; 95(4):660-73. PubMed ID: 11596961
[TBL] [Abstract][Full Text] [Related]
18. A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome.
Tanimoto Y; Yokozeki M; Hiura K; Matsumoto K; Nakanishi H; Matsumoto T; Marie PJ; Moriyama K
J Biol Chem; 2004 Oct; 279(44):45926-34. PubMed ID: 15310757
[TBL] [Abstract][Full Text] [Related]
19. BCL11B regulates sutural patency in the mouse craniofacial skeleton.
Kyrylkova K; Iwaniec UT; Philbrick KA; Leid M
Dev Biol; 2016 Jul; 415(2):251-260. PubMed ID: 26453795
[TBL] [Abstract][Full Text] [Related]
20. FGF/FGFR signaling coordinates skull development by modulating magnitude of morphological integration: evidence from Apert syndrome mouse models.
Martínez-Abadías N; Heuzé Y; Wang Y; Jabs EW; Aldridge K; Richtsmeier JT
PLoS One; 2011; 6(10):e26425. PubMed ID: 22053191
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]