These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 24636344)

  • 1. High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity.
    Walter GM; Raveh A; Mok SA; McQuade TJ; Arevang CJ; Schultz PJ; Smith MC; Asare S; Cruz PG; Wisen S; Matainaho T; Sherman DH; Gestwicki JE
    Chem Biol Drug Des; 2014 Apr; 83(4):440-9. PubMed ID: 24636344
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.
    Chafekar SM; Wisén S; Thompson AD; Echeverria A; Walter GM; Evans CG; Makley LN; Gestwicki JE; Duennwald ML
    ACS Chem Biol; 2012 Sep; 7(9):1556-64. PubMed ID: 22709427
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes.
    Walter GM; Smith MC; Wisén S; Basrur V; Elenitoba-Johnson KS; Duennwald ML; Kumar A; Gestwicki JE
    J Biol Chem; 2011 Nov; 286(47):40486-93. PubMed ID: 21969373
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins.
    Krobitsch S; Lindquist S
    Proc Natl Acad Sci U S A; 2000 Feb; 97(4):1589-94. PubMed ID: 10677504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1.
    Meriin AB; Zhang X; He X; Newnam GP; Chernoff YO; Sherman MY
    J Cell Biol; 2002 Jun; 157(6):997-1004. PubMed ID: 12058016
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.
    Zhang X; Smith DL; Meriin AB; Engemann S; Russel DE; Roark M; Washington SL; Maxwell MM; Marsh JL; Thompson LM; Wanker EE; Young AB; Housman DE; Bates GP; Sherman MY; Kazantsev AG
    Proc Natl Acad Sci U S A; 2005 Jan; 102(3):892-7. PubMed ID: 15642944
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecule inducers of heat-shock response reduce polyQ-mediated huntingtin aggregation. A possible therapeutic strategy.
    Herbst M; Wanker EE
    Neurodegener Dis; 2007; 4(2-3):254-60. PubMed ID: 17596719
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Measurement of Chaperone-Mediated Effects on Polyglutamine Protein Aggregation by the Filter Trap Assay.
    van Waarde-Verhagen MAWH; Kampinga HH
    Methods Mol Biol; 2018; 1709():59-74. PubMed ID: 29177651
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity.
    Duennwald ML; Lindquist S
    Genes Dev; 2008 Dec; 22(23):3308-19. PubMed ID: 19015277
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease.
    Wetzel R
    Acc Chem Res; 2020 Oct; 53(10):2347-2357. PubMed ID: 32975927
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.
    Behrends C; Langer CA; Boteva R; Böttcher UM; Stemp MJ; Schaffar G; Rao BV; Giese A; Kretzschmar H; Siegers K; Hartl FU
    Mol Cell; 2006 Sep; 23(6):887-97. PubMed ID: 16973440
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sfp1 links TORC1 and cell growth regulation to the yeast SAGA-complex component Tra1 in response to polyQ proteotoxicity.
    Jiang Y; Berg MD; Genereaux J; Ahmed K; Duennwald ML; Brandl CJ; Lajoie P
    Traffic; 2019 Apr; 20(4):267-283. PubMed ID: 30740854
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel mechanism of Hsp70 chaperone-mediated prevention of polyglutamine aggregates in a cellular model of huntington disease.
    Guzhova IV; Lazarev VF; Kaznacheeva AV; Ippolitova MV; Muronetz VI; Kinev AV; Margulis BA
    Hum Mol Genet; 2011 Oct; 20(20):3953-63. PubMed ID: 21775503
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mimicking proteasomal release of polyglutamine peptides initiates aggregation and toxicity.
    Raspe M; Gillis J; Krol H; Krom S; Bosch K; van Veen H; Reits E
    J Cell Sci; 2009 Sep; 122(Pt 18):3262-71. PubMed ID: 19690053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells.
    Kar K; Arduini I; Drombosky KW; van der Wel PC; Wetzel R
    J Mol Biol; 2014 Feb; 426(4):816-29. PubMed ID: 24291210
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model.
    Schiffer NW; Broadley SA; Hirschberger T; Tavan P; Kretzschmar HA; Giese A; Haass C; Hartl FU; Schmid B
    J Biol Chem; 2007 Mar; 282(12):9195-203. PubMed ID: 17170113
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation.
    Yamanaka T; Wong HK; Tosaki A; Bauer PO; Wada K; Kurosawa M; Shimogori T; Hattori N; Nukina N
    PLoS One; 2014; 9(4):e93891. PubMed ID: 24705917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.
    Gillis J; Schipper-Krom S; Juenemann K; Gruber A; Coolen S; van den Nieuwendijk R; van Veen H; Overkleeft H; Goedhart J; Kampinga HH; Reits EA
    J Biol Chem; 2013 Jun; 288(24):17225-37. PubMed ID: 23612975
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth assays to assess polyglutamine toxicity in yeast.
    Duennwald ML
    J Vis Exp; 2012 Mar; (61):e3461. PubMed ID: 22415521
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin.
    Chafekar SM; Duennwald ML
    PLoS One; 2012; 7(5):e37929. PubMed ID: 22649566
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.