BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

408 related articles for article (PubMed ID: 24636985)

  • 1. Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis.
    Wu T; Zhao F; Gao B; Tan C; Yagishita N; Nakajima T; Wong PK; Chapman E; Fang D; Zhang DD
    Genes Dev; 2014 Apr; 28(7):708-22. PubMed ID: 24636985
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species.
    Wang L; Wang M; Niu H; Zhi Y; Li S; He X; Ren Z; Wen S; Wu L; Wen S; Zhang R; Wen Z; Yang J; Zhang X; Chen Y; Qian X; Shi G
    J Mol Cell Cardiol; 2024 Feb; 187():51-64. PubMed ID: 38171043
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human HRD1 promoter carries a functional unfolded protein response element to which XBP1 but not ATF6 directly binds.
    Yamamoto K; Suzuki N; Wada T; Okada T; Yoshida H; Kaufman RJ; Mori K
    J Biochem; 2008 Oct; 144(4):477-86. PubMed ID: 18664523
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The E3 Ubiquitin Ligase Ring Finger Protein 5 Ameliorates NASH Through Ubiquitin-Mediated Degradation of 3-Hydroxy-3-Methylglutaryl CoA Reductase Degradation Protein 1.
    Yang Q; Chen X; Zhang Y; Hu S; Hu F; Huang Y; Ma T; Hu H; Tian H; Tian S; Ji YX; She ZG; Zhang P; Zhang XJ; Hu Y; Yang H; Yuan Y; Li H
    Hepatology; 2021 Dec; 74(6):3018-3036. PubMed ID: 34272738
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation.
    Zhang J; Zhang J; Ni H; Wang Y; Katwal G; Zhao Y; Sun K; Wang M; Li Q; Chen G; Miao Y; Gong N
    Cell Death Discov; 2021 Mar; 7(1):44. PubMed ID: 33654072
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy.
    Hernández-Gea V; Hilscher M; Rozenfeld R; Lim MP; Nieto N; Werner S; Devi LA; Friedman SL
    J Hepatol; 2013 Jul; 59(1):98-104. PubMed ID: 23485523
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program.
    Kim H; Wei J; Song Z; Mottillo E; Samavati L; Zhang R; Li L; Chen X; Jena BP; Lin JD; Fang D; Zhang K
    Mol Metab; 2021 Jul; 49():101192. PubMed ID: 33592335
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
    Huang Y; Sun Y; Cao Y; Sun H; Li M; You H; Su D; Li Y; Liang X
    Cell Death Dis; 2017 Dec; 8(12):3202. PubMed ID: 29233968
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
    Liu Z; Nan P; Gong Y; Tian L; Zheng Y; Wu Z
    Biomed Pharmacother; 2023 Aug; 164():114897. PubMed ID: 37224754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Physiological Roles of Ubiquitin Ligases Related to the Endoplasmic Reticulum].
    Kaneko M
    Yakugaku Zasshi; 2016; 136(6):805-9. PubMed ID: 27252059
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway.
    Liu Y; Tao S; Liao L; Li Y; Li H; Li Z; Lin L; Wan X; Yang X; Chen L
    Nat Commun; 2020 Jan; 11(1):348. PubMed ID: 31953436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine-induced ER stress response.
    Xu Y; Melo-Cardenas J; Zhang Y; Gau I; Wei J; Montauti E; Zhang Y; Gao B; Jin H; Sun Z; Lee SM; Fang D
    JCI Insight; 2019 Mar; 4(5):. PubMed ID: 30843874
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention.
    Harder B; Jiang T; Wu T; Tao S; Rojo de la Vega M; Tian W; Chapman E; Zhang DD
    Biochem Soc Trans; 2015 Aug; 43(4):680-6. PubMed ID: 26551712
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
    Lo SC; Hannink M
    Mol Cell Biol; 2006 Feb; 26(4):1235-44. PubMed ID: 16449638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
    Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
    Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SMURF1 attenuates endoplasmic reticulum stress by promoting the degradation of KEAP1 to activate NRF2 antioxidant pathway.
    Dong L; Xu M; Li Y; Xu W; Wu C; Zheng H; Xiao Z; Sun G; Ding L; Li X; Li W; Zhou L; Xia Q
    Cell Death Dis; 2023 Jun; 14(6):361. PubMed ID: 37316499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Molecular pharmacological studies on the protection mechanism against endoplasmic reticulum stress-induced neurodegenerative disease].
    Kaneko M
    Yakugaku Zasshi; 2012; 132(12):1437-42. PubMed ID: 23208051
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HRD1-induced TMEM2 ubiquitination promotes ER stress-mediated apoptosis through a non-canonical pathway in intestinal ischemia/reperfusion.
    Zhao X; Liu D; Zhao Y; Wang Z; Wang Y; Chen Z; Ning S; Wang G; Meng L; Yao J; Tian X
    Cell Death Dis; 2024 Feb; 15(2):154. PubMed ID: 38378757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.
    Harada K; Kato M; Nakamura N
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827840
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T; Chu K; Kodama R; Byun S; Yoon KW; Hiraki M; Mandinova A; Lee SW
    Oncotarget; 2015 Aug; 6(24):19990-20001. PubMed ID: 26254280
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.