203 related articles for article (PubMed ID: 24649848)
1. Discovery of a potent and selective α3β4 nicotinic acetylcholine receptor antagonist from an α-conotoxin synthetic combinatorial library.
Chang YP; Banerjee J; Dowell C; Wu J; Gyanda R; Houghten RA; Toll L; McIntosh JM; Armishaw CJ
J Med Chem; 2014 Apr; 57(8):3511-21. PubMed ID: 24649848
[TBL] [Abstract][Full Text] [Related]
2. A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.
Armishaw CJ; Singh N; Medina-Franco JL; Clark RJ; Scott KC; Houghten RA; Jensen AA
J Biol Chem; 2010 Jan; 285(3):1809-21. PubMed ID: 19901032
[TBL] [Abstract][Full Text] [Related]
3. Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.
Kompella SN; Hung A; Clark RJ; Marí F; Adams DJ
J Biol Chem; 2015 Jan; 290(2):1039-48. PubMed ID: 25411242
[TBL] [Abstract][Full Text] [Related]
4. A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors.
Luo S; Zhangsun D; Schroeder CI; Zhu X; Hu Y; Wu Y; Weltzin MM; Eberhard S; Kaas Q; Craik DJ; McIntosh JM; Whiteaker P
FASEB J; 2014 Apr; 28(4):1842-53. PubMed ID: 24398291
[TBL] [Abstract][Full Text] [Related]
5. α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors.
van Hout M; Valdes A; Christensen SB; Tran PT; Watkins M; Gajewiak J; Jensen AA; Olivera BM; McIntosh JM
Neuropharmacology; 2019 Oct; 157():107691. PubMed ID: 31255696
[TBL] [Abstract][Full Text] [Related]
6. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins.
Cuny H; Kompella SN; Tae HS; Yu R; Adams DJ
J Biol Chem; 2016 Nov; 291(45):23779-23792. PubMed ID: 27646000
[TBL] [Abstract][Full Text] [Related]
7. Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors.
Luo S; Zhangsun D; Zhu X; Wu Y; Hu Y; Christensen S; Harvey PJ; Akcan M; Craik DJ; McIntosh JM
J Med Chem; 2013 Dec; 56(23):9655-63. PubMed ID: 24200193
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of α-conotoxin GID analogues as selective α4β2 nicotinic acetylcholine receptor antagonists.
Banerjee J; Yongye AB; Chang YP; Gyanda R; Medina-Franco JL; Armishaw CJ
Biopolymers; 2014 Jan; 102(1):78-87. PubMed ID: 24122487
[TBL] [Abstract][Full Text] [Related]
9. Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist.
Yu J; Zhu X; Harvey PJ; Kaas Q; Zhangsun D; Craik DJ; Luo S
J Med Chem; 2018 Oct; 61(20):9256-9265. PubMed ID: 30252466
[TBL] [Abstract][Full Text] [Related]
10. α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells.
Hone AJ; McIntosh JM; Azam L; Lindstrom J; Lucero L; Whiteaker P; Passas J; Blázquez J; Albillos A
Mol Pharmacol; 2015 Nov; 88(5):881-93. PubMed ID: 26330550
[TBL] [Abstract][Full Text] [Related]
11. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs.
Franco A; Kompella SN; Akondi KB; Melaun C; Daly NL; Luetje CW; Alewood PF; Craik DJ; Adams DJ; Marí F
Biochem Pharmacol; 2012 Feb; 83(3):419-26. PubMed ID: 22108175
[TBL] [Abstract][Full Text] [Related]
12. Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor.
Abraham N; Healy M; Ragnarsson L; Brust A; Alewood PF; Lewis RJ
Sci Rep; 2017 Mar; 7():45466. PubMed ID: 28361878
[TBL] [Abstract][Full Text] [Related]
13. Structural and Functional Characterization of a Novel α-Conotoxin Mr1.7 from Conus marmoreus Targeting Neuronal nAChR α3β2, α9α10 and α6/α3β2β3 Subtypes.
Wang S; Zhao C; Liu Z; Wang X; Liu N; Du W; Dai Q
Mar Drugs; 2015 May; 13(6):3259-75. PubMed ID: 26023835
[TBL] [Abstract][Full Text] [Related]
14. Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor.
Luo S; Akondi KB; Zhangsun D; Wu Y; Zhu X; Hu Y; Christensen S; Dowell C; Daly NL; Craik DJ; Wang CI; Lewis RJ; Alewood PF; Michael McIntosh J
J Biol Chem; 2010 Apr; 285(16):12355-66. PubMed ID: 20145249
[TBL] [Abstract][Full Text] [Related]
15. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes.
Sharples CG; Kaiser S; Soliakov L; Marks MJ; Collins AC; Washburn M; Wright E; Spencer JA; Gallagher T; Whiteaker P; Wonnacott S
J Neurosci; 2000 Apr; 20(8):2783-91. PubMed ID: 10751429
[TBL] [Abstract][Full Text] [Related]
16. Alpha-conotoxin Arenatus IB[V11L,V16D] [corrected] is a potent and selective antagonist at rat and human native alpha7 nicotinic acetylcholine receptors.
Innocent N; Livingstone PD; Hone A; Kimura A; Young T; Whiteaker P; McIntosh JM; Wonnacott S
J Pharmacol Exp Ther; 2008 Nov; 327(2):529-37. PubMed ID: 18664588
[TBL] [Abstract][Full Text] [Related]
17. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors.
Grishin AA; Wang CI; Muttenthaler M; Alewood PF; Lewis RJ; Adams DJ
J Biol Chem; 2010 Jul; 285(29):22254-63. PubMed ID: 20466726
[TBL] [Abstract][Full Text] [Related]
18. Alpha-conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors.
Nicke A; Samochocki M; Loughnan ML; Bansal PS; Maelicke A; Lewis RJ
FEBS Lett; 2003 Nov; 554(1-2):219-23. PubMed ID: 14596943
[TBL] [Abstract][Full Text] [Related]
19. Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors.
Kompella SN; Cuny H; Hung A; Adams DJ
Mol Pharmacol; 2015 Dec; 88(6):993-1001. PubMed ID: 26438212
[TBL] [Abstract][Full Text] [Related]
20. α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors.
Wu Y; Zhangsun D; Zhu X; Kaas Q; Zhangsun M; Harvey PJ; Craik DJ; McIntosh JM; Luo S
J Med Chem; 2017 Jul; 60(13):5826-5833. PubMed ID: 28603989
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
