These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia. Siska PJ; van der Windt GJ; Kishton RJ; Cohen S; Eisner W; MacIver NJ; Kater AP; Weinberg JB; Rathmell JC J Immunol; 2016 Sep; 197(6):2532-40. PubMed ID: 27511728 [TBL] [Abstract][Full Text] [Related]
7. E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer. Ladu S; Calvisi DF; Conner EA; Farina M; Factor VM; Thorgeirsson SS Gastroenterology; 2008 Oct; 135(4):1322-32. PubMed ID: 18722373 [TBL] [Abstract][Full Text] [Related]
8. 4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells. Yun S; Vincelette ND; Knorr KL; Almada LL; Schneider PA; Peterson KL; Flatten KS; Dai H; Pratz KW; Hess AD; Smith BD; Karp JE; Hendrickson AE; Fernandez-Zapico ME; Kaufmann SH Blood; 2016 Jun; 127(22):2711-22. PubMed ID: 26917778 [TBL] [Abstract][Full Text] [Related]
9. PI3K/mTOR inhibition upregulates NOTCH-MYC signalling leading to an impaired cytotoxic response. Shepherd C; Banerjee L; Cheung CW; Mansour MR; Jenkinson S; Gale RE; Khwaja A Leukemia; 2013 Mar; 27(3):650-60. PubMed ID: 23038273 [TBL] [Abstract][Full Text] [Related]
10. Rapamycin interacts synergistically with idarubicin to induce T-leukemia cell apoptosis in vitro and in a mesenchymal stem cell simulated drug-resistant microenvironment via Akt/mammalian target of rapamycin and extracellular signal-related kinase signaling pathways. Wu KN; Zhao YM; He Y; Wang BS; Du KL; Fu S; Hu KM; Zhang LF; Liu LZ; Hu YX; Wang YJ; Huang H Leuk Lymphoma; 2014 Mar; 55(3):668-76. PubMed ID: 23741975 [TBL] [Abstract][Full Text] [Related]
11. Signaling by FGF Receptor 2, Not FGF Receptor 1, Regulates Myelin Thickness through Activation of ERK1/2-MAPK, Which Promotes mTORC1 Activity in an Akt-Independent Manner. Furusho M; Ishii A; Bansal R J Neurosci; 2017 Mar; 37(11):2931-2946. PubMed ID: 28193689 [TBL] [Abstract][Full Text] [Related]
12. NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia. Guo D; Teng Q; Ji C Leuk Lymphoma; 2011 Jul; 52(7):1200-10. PubMed ID: 21463127 [TBL] [Abstract][Full Text] [Related]
13. Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism. Chen CH; Kiyan V; Zhylkibayev AA; Kazyken D; Bulgakova O; Page KE; Bersimbaev RI; Spooner E; Sarbassov DD J Biol Chem; 2013 Sep; 288(38):27019-27030. PubMed ID: 23928304 [TBL] [Abstract][Full Text] [Related]
14. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells. Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280 [TBL] [Abstract][Full Text] [Related]
15. mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc. Masui K; Tanaka K; Akhavan D; Babic I; Gini B; Matsutani T; Iwanami A; Liu F; Villa GR; Gu Y; Campos C; Zhu S; Yang H; Yong WH; Cloughesy TF; Mellinghoff IK; Cavenee WK; Shaw RJ; Mischel PS Cell Metab; 2013 Nov; 18(5):726-39. PubMed ID: 24140020 [TBL] [Abstract][Full Text] [Related]
16. SOX2 promotes tumor growth of esophageal squamous cell carcinoma through the AKT/mammalian target of rapamycin complex 1 signaling pathway. Gen Y; Yasui K; Nishikawa T; Yoshikawa T Cancer Sci; 2013 Jul; 104(7):810-6. PubMed ID: 23510069 [TBL] [Abstract][Full Text] [Related]
17. Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila. Kuo Y; Huang H; Cai T; Wang T Sci Rep; 2015 May; 5():10339. PubMed ID: 25999153 [TBL] [Abstract][Full Text] [Related]
18. Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer. Yang F; Deng R; Qian XJ; Chang SH; Wu XQ; Qin J; Feng GK; Ding K; Zhu XF Cell Death Dis; 2014 Mar; 5(3):e1114. PubMed ID: 24625973 [TBL] [Abstract][Full Text] [Related]