BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 24652283)

  • 1. Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation.
    Hong S; Zhao B; Lombard DB; Fingar DC; Inoki K
    J Biol Chem; 2014 May; 289(19):13132-41. PubMed ID: 24652283
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.
    Liu D; Bordicchia M; Zhang C; Fang H; Wei W; Li JL; Guilherme A; Guntur K; Czech MP; Collins S
    J Clin Invest; 2016 May; 126(5):1704-16. PubMed ID: 27018708
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells.
    Ahmed AR; Owens RJ; Stubbs CD; Parker AW; Hitchman R; Yadav RB; Dumoux M; Hawes C; Botchway SW
    Sci Rep; 2019 Mar; 9(1):3408. PubMed ID: 30833605
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1.
    Ben-Hur V; Denichenko P; Siegfried Z; Maimon A; Krainer A; Davidson B; Karni R
    Cell Rep; 2013 Jan; 3(1):103-15. PubMed ID: 23273915
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors.
    Melick CH; Jewell JL
    Biochem J; 2020 May; 477(10):1847-1863. PubMed ID: 32347294
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Butyrate inhibits the proliferation and induces the apoptosis of colorectal cancer HCT116 cells via the deactivation of mTOR/S6K1 signaling mediated partly by SIRT1 downregulation.
    Cao M; Zhang Z; Han S; Lu X
    Mol Med Rep; 2019 May; 19(5):3941-3947. PubMed ID: 30864709
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).
    Keshwani MM; von Daake S; Newton AC; Harris TK; Taylor SS
    J Biol Chem; 2011 Jul; 286(26):23552-8. PubMed ID: 21561857
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling.
    Gao S; Duan C; Gao G; Wang X; Yang H
    Int J Biochem Cell Biol; 2015 Jul; 64():25-33. PubMed ID: 25813876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity.
    Bartley CM; O'Keefe RA; Bordey A
    PLoS One; 2014; 9(5):e96956. PubMed ID: 24806451
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elevated protein kinase D3 (PKD3) expression supports proliferation of triple-negative breast cancer cells and contributes to mTORC1-S6K1 pathway activation.
    Huck B; Duss S; Hausser A; Olayioye MA
    J Biol Chem; 2014 Feb; 289(6):3138-47. PubMed ID: 24337579
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.
    Chen CH; Kiyan V; Zhylkibayev AA; Kazyken D; Bulgakova O; Page KE; Bersimbaev RI; Spooner E; Sarbassov DD
    J Biol Chem; 2013 Sep; 288(38):27019-27030. PubMed ID: 23928304
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.
    Arif A; Terenzi F; Potdar AA; Jia J; Sacks J; China A; Halawani D; Vasu K; Li X; Brown JM; Chen J; Kozma SC; Thomas G; Fox PL
    Nature; 2017 Feb; 542(7641):357-361. PubMed ID: 28178239
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PKD1 is downregulated in non-small cell lung cancer and mediates the feedback inhibition of mTORC1-S6K1 axis in response to phorbol ester.
    Ni Y; Wang L; Zhang J; Pang Z; Liu Q; Du J
    Int J Biochem Cell Biol; 2015 Mar; 60():34-42. PubMed ID: 25578563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.
    Tandelilin AA; Hirase T; Hudoyo AW; Cheng J; Toyama K; Morisaki H; Morisaki T
    BMC Endocr Disord; 2015 Mar; 15():11. PubMed ID: 25887856
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fisetin regulates obesity by targeting mTORC1 signaling.
    Jung CH; Kim H; Ahn J; Jeon TI; Lee DH; Ha TY
    J Nutr Biochem; 2013 Aug; 24(8):1547-54. PubMed ID: 23517912
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
    J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.
    Dunlop EA; Hunt DK; Acosta-Jaquez HA; Fingar DC; Tee AR
    Autophagy; 2011 Jul; 7(7):737-47. PubMed ID: 21460630
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of IRS1 at serine 307 in response to insulin in human adipocytes is not likely to be catalyzed by p70 ribosomal S6 kinase.
    Rajan MR; Fagerholm S; Jönsson C; Kjølhede P; Turkina MV; Strålfors P
    PLoS One; 2013; 8(4):e59725. PubMed ID: 23565163
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.