These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability. Horejsí Z; Takai H; Adelman CA; Collis SJ; Flynn H; Maslen S; Skehel JM; de Lange T; Boulton SJ Mol Cell; 2010 Sep; 39(6):839-50. PubMed ID: 20864032 [TBL] [Abstract][Full Text] [Related]
3. Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1. Pal M; Morgan M; Phelps SE; Roe SM; Parry-Morris S; Downs JA; Polier S; Pearl LH; Prodromou C Structure; 2014 Jun; 22(6):805-18. PubMed ID: 24794838 [TBL] [Abstract][Full Text] [Related]
4. RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Martino F; Pal M; Muñoz-Hernández H; Rodríguez CF; Núñez-Ramírez R; Gil-Carton D; Degliesposti G; Skehel JM; Roe SM; Prodromou C; Pearl LH; Llorca O Nat Commun; 2018 Apr; 9(1):1501. PubMed ID: 29662061 [TBL] [Abstract][Full Text] [Related]
5. RPAP3 C-Terminal Domain: A Conserved Domain for the Assembly of R2TP Co-Chaperone Complexes. Rodríguez CF; Llorca O Cells; 2020 May; 9(5):. PubMed ID: 32384603 [TBL] [Abstract][Full Text] [Related]
6. MRE11 stability is regulated by CK2-dependent interaction with R2TP complex. von Morgen P; Burdova K; Flower TG; O'Reilly NJ; Boulton SJ; Smerdon SJ; Macurek L; Hořejší Z Oncogene; 2017 Aug; 36(34):4943-4950. PubMed ID: 28436950 [TBL] [Abstract][Full Text] [Related]
7. Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. Henri J; Chagot ME; Bourguet M; Abel Y; Terral G; Maurizy C; Aigueperse C; Georgescauld F; Vandermoere F; Saint-Fort R; Behm-Ansmant I; Charpentier B; Pradet-Balade B; Verheggen C; Bertrand E; Meyer P; Cianférani S; Manival X; Quinternet M Structure; 2018 Sep; 26(9):1196-1209.e8. PubMed ID: 30033218 [TBL] [Abstract][Full Text] [Related]
8. Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes. Seraphim TV; Nano N; Cheung YWS; Aluksanasuwan S; Colleti C; Mao YQ; Bhandari V; Young G; Höll L; Phanse S; Gordiyenko Y; Southworth DR; Robinson CV; Thongboonkerd V; Gava LM; Borges JC; Babu M; Barbosa LRS; Ramos CHI; Kukura P; Houry WA Structure; 2022 Jan; 30(1):156-171.e12. PubMed ID: 34492227 [TBL] [Abstract][Full Text] [Related]
9. PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription. Kamano Y; Saeki M; Egusa H; Kakihara Y; Houry WA; Yatani H; Kamisaki Y FEBS Lett; 2013 Oct; 587(20):3303-8. PubMed ID: 24036451 [TBL] [Abstract][Full Text] [Related]
10. Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone. Pal M; Muñoz-Hernandez H; Bjorklund D; Zhou L; Degliesposti G; Skehel JM; Hesketh EL; Thompson RF; Pearl LH; Llorca O; Prodromou C Cell Rep; 2021 Jul; 36(1):109317. PubMed ID: 34233195 [TBL] [Abstract][Full Text] [Related]
11. Substrate recognition and function of the R2TP complex in response to cellular stress. von Morgen P; Hořejší Z; Macurek L Front Genet; 2015; 6():69. PubMed ID: 25767478 [TBL] [Abstract][Full Text] [Related]
12. The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones. Maurizy C; Quinternet M; Abel Y; Verheggen C; Santo PE; Bourguet M; C F Paiva A; Bragantini B; Chagot ME; Robert MC; Abeza C; Fabre P; Fort P; Vandermoere F; M F Sousa P; Rain JC; Charpentier B; Cianférani S; Bandeiras TM; Pradet-Balade B; Manival X; Bertrand E Nat Commun; 2018 May; 9(1):2093. PubMed ID: 29844425 [TBL] [Abstract][Full Text] [Related]
13. HSP90 and the R2TP co-chaperone complex: building multi-protein machineries essential for cell growth and gene expression. Boulon S; Bertrand E; Pradet-Balade B RNA Biol; 2012 Feb; 9(2):148-54. PubMed ID: 22418846 [TBL] [Abstract][Full Text] [Related]
14. Advances on the Structure of the R2TP/Prefoldin-like Complex. Muñoz-Hernández H; Pal M; Rodríguez CF; Prodromou C; Pearl LH; Llorca O Adv Exp Med Biol; 2018; 1106():73-83. PubMed ID: 30484153 [TBL] [Abstract][Full Text] [Related]
15. Tah1 helix-swap dimerization prevents mixed Hsp90 co-chaperone complexes. Morgan RM; Pal M; Roe SM; Pearl LH; Prodromou C Acta Crystallogr D Biol Crystallogr; 2015 May; 71(Pt 5):1197-206. PubMed ID: 25945584 [TBL] [Abstract][Full Text] [Related]
16. Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Muñoz-Hernández H; Pal M; Rodríguez CF; Fernandez-Leiro R; Prodromou C; Pearl LH; Llorca O Sci Adv; 2019 May; 5(5):eaaw1616. PubMed ID: 31049401 [TBL] [Abstract][Full Text] [Related]
17. Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries. Benbahouche Nel H; Iliopoulos I; Török I; Marhold J; Henri J; Kajava AV; Farkaš R; Kempf T; Schnölzer M; Meyer P; Kiss I; Bertrand E; Mechler BM; Pradet-Balade B J Biol Chem; 2014 Feb; 289(9):6236-47. PubMed ID: 24394412 [TBL] [Abstract][Full Text] [Related]
18. HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II. Boulon S; Pradet-Balade B; Verheggen C; Molle D; Boireau S; Georgieva M; Azzag K; Robert MC; Ahmad Y; Neel H; Lamond AI; Bertrand E Mol Cell; 2010 Sep; 39(6):912-924. PubMed ID: 20864038 [TBL] [Abstract][Full Text] [Related]
19. The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System. Rivera-Calzada A; Pal M; Muñoz-Hernández H; Luque-Ortega JR; Gil-Carton D; Degliesposti G; Skehel JM; Prodromou C; Pearl LH; Llorca O Structure; 2017 Jul; 25(7):1145-1152.e4. PubMed ID: 28648606 [TBL] [Abstract][Full Text] [Related]
20. PIH1D1, a subunit of R2TP complex, inhibits doxorubicin-induced apoptosis. Inoue M; Saeki M; Egusa H; Niwa H; Kamisaki Y Biochem Biophys Res Commun; 2010 Dec; 403(3-4):340-4. PubMed ID: 21078300 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]