163 related articles for article (PubMed ID: 24657156)
21. Thioredoxin inhibits MPK38-induced ASK1, TGF-β, and p53 function in a phosphorylation-dependent manner.
Manoharan R; Seong HA; Ha H
Free Radic Biol Med; 2013 Oct; 63():313-24. PubMed ID: 23747528
[TBL] [Abstract][Full Text] [Related]
22. Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma.
Kiseljak-Vassiliades K; Zhang Y; Kar A; Razzaghi R; Xu M; Gowan K; Raeburn CD; Albuja-Cruz M; Jones KL; Somerset H; Fishbein L; Leong S; Wierman ME
Endocrinology; 2018 Jul; 159(7):2532-2544. PubMed ID: 29790920
[TBL] [Abstract][Full Text] [Related]
23. MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway.
Xu Q; Ge Q; Zhou Y; Yang B; Yang Q; Jiang S; Jiang R; Ai Z; Zhang Z; Teng Y
EBioMedicine; 2020 Jan; 51():102609. PubMed ID: 31915116
[TBL] [Abstract][Full Text] [Related]
24. Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers.
Gray D; Jubb AM; Hogue D; Dowd P; Kljavin N; Yi S; Bai W; Frantz G; Zhang Z; Koeppen H; de Sauvage FJ; Davis DP
Cancer Res; 2005 Nov; 65(21):9751-61. PubMed ID: 16266996
[TBL] [Abstract][Full Text] [Related]
25. Crystal structure of Maternal Embryonic Leucine Zipper Kinase (MELK) in complex with dorsomorphin (Compound C).
Rembacz KP; Zrubek KM; Golik P; Michalik K; Bogusz J; Wladyka B; Romanowska M; Dubin G
Arch Biochem Biophys; 2019 Aug; 671():1-7. PubMed ID: 31108049
[TBL] [Abstract][Full Text] [Related]
26. Pharmacological inhibition of MELK restricts ferroptosis and the inflammatory response in colitis and colitis-propelled carcinogenesis.
Tang B; Zhu J; Fang S; Wang Y; Vinothkumar R; Li M; Weng Q; Zheng L; Yang Y; Qiu R; Xu M; Zhao Z; Ji J
Free Radic Biol Med; 2021 Aug; 172():312-329. PubMed ID: 34144192
[TBL] [Abstract][Full Text] [Related]
27. MELK Inhibition Effectively Suppresses Growth of Glioblastoma and Cancer Stem-Like Cells by Blocking AKT and FOXM1 Pathways.
Zhang X; Wang J; Wang Y; Liu G; Li H; Yu J; Wu R; Liang J; Yu R; Liu X
Front Oncol; 2020; 10():608082. PubMed ID: 33520717
[TBL] [Abstract][Full Text] [Related]
28. Mass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells.
McDonald IM; Grant GD; East MP; Gilbert TSK; Wilkerson EM; Goldfarb D; Beri J; Herring LE; Vaziri C; Cook JG; Emanuele MJ; Graves LM
J Biol Chem; 2020 Feb; 295(8):2359-2374. PubMed ID: 31896573
[TBL] [Abstract][Full Text] [Related]
29. MELK is not necessary for the proliferation of basal-like breast cancer cells.
Huang HT; Seo HS; Zhang T; Wang Y; Jiang B; Li Q; Buckley DL; Nabet B; Roberts JM; Paulk J; Dastjerdi S; Winter GE; McLauchlan H; Moran J; Bradner JE; Eck MJ; Dhe-Paganon S; Zhao JJ; Gray NS
Elife; 2017 Sep; 6():. PubMed ID: 28926338
[TBL] [Abstract][Full Text] [Related]
30. Thr55 phosphorylation of p21 by MPK38/MELK ameliorates defects in glucose, lipid, and energy metabolism in diet-induced obese mice.
Seong HA; Ha H
Cell Death Dis; 2019 May; 10(6):380. PubMed ID: 31097688
[TBL] [Abstract][Full Text] [Related]
31. Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
Lin ML; Park JH; Nishidate T; Nakamura Y; Katagiri T
Breast Cancer Res; 2007; 9(1):R17. PubMed ID: 17280616
[TBL] [Abstract][Full Text] [Related]
32. Maternal embryonic leucine zipper kinase: A novel biomarker and a potential therapeutic target of cervical cancer.
Wang J; Wang Y; Shen F; Xu Y; Zhang Y; Zou X; Zhou J; Chen Y
Cancer Med; 2018 Nov; 7(11):5665-5678. PubMed ID: 30334367
[TBL] [Abstract][Full Text] [Related]
33. DAXX ameliorates metabolic dysfunction in mice with diet-induced obesity by activating the AMP-activated protein kinase-related kinase MPK38/MELK.
Seong HA; Manoharan R; Ha H
Biochem Biophys Res Commun; 2021 Oct; 572():164-170. PubMed ID: 34365141
[TBL] [Abstract][Full Text] [Related]
34. Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma.
Cigliano A; Pilo MG; Mela M; Ribback S; Dombrowski F; Pes GM; Cossu A; Evert M; Calvisi DF; Utpatel K
Medicina (Kaunas); 2019 Dec; 56(1):. PubMed ID: 31861475
[No Abstract] [Full Text] [Related]
35. MELK is a novel therapeutic target in high-risk neuroblastoma.
Guan S; Lu J; Zhao Y; Yu Y; Li H; Chen Z; Shi Z; Liang H; Wang M; Guo K; Chen X; Sun W; Bieerkehazhi S; Xu X; Sun S; Agarwal S; Yang J
Oncotarget; 2018 Jan; 9(2):2591-2602. PubMed ID: 29416794
[TBL] [Abstract][Full Text] [Related]
36. Structural basis for the regulation of maternal embryonic leucine zipper kinase.
Cao LS; Wang J; Chen Y; Deng H; Wang ZX; Wu JW
PLoS One; 2013; 8(7):e70031. PubMed ID: 23922895
[TBL] [Abstract][Full Text] [Related]
37. Ablation of AMPK-Related Kinase MPK38/MELK Leads to Male-Specific Obesity in Aged Mature Adult Mice.
Seong HA; Ha H
Diabetes; 2021 Feb; 70(2):386-399. PubMed ID: 33268463
[TBL] [Abstract][Full Text] [Related]
38. Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Chlenski A; Park C; Dobratic M; Salwen HR; Budke B; Park JH; Miller R; Applebaum MA; Wilkinson E; Nakamura Y; Connell PP; Cohn SL
Mol Cancer Ther; 2019 Mar; 18(3):507-516. PubMed ID: 30674566
[TBL] [Abstract][Full Text] [Related]
39. Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight.
Touré BB; Giraldes J; Smith T; Sprague ER; Wang Y; Mathieu S; Chen Z; Mishina Y; Feng Y; Yan-Neale Y; Shakya S; Chen D; Meyer M; Puleo D; Brazell JT; Straub C; Sage D; Wright K; Yuan Y; Chen X; Duca J; Kim S; Tian L; Martin E; Hurov K; Shao W
J Med Chem; 2016 May; 59(10):4711-23. PubMed ID: 27187609
[TBL] [Abstract][Full Text] [Related]
40. Benzo[c][2,7]naphthyridines as inhibitors of PDK-1.
Kim KH; Wissner A; Floyd MB; Fraser HL; Wang YD; Dushin RG; Hu Y; Olland A; Guo B; Arndt K
Bioorg Med Chem Lett; 2009 Sep; 19(17):5225-8. PubMed ID: 19628388
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]