BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 24658326)

  • 1. MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme.
    Knubel KH; Pernu BM; Sufit A; Nelson S; Pierce AM; Keating AK
    Oncotarget; 2014 Mar; 5(5):1338-51. PubMed ID: 24658326
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo.
    Onken J; Torka R; Korsing S; Radke J; Krementeskaia I; Nieminen M; Bai X; Ullrich A; Heppner F; Vajkoczy P
    Oncotarget; 2016 Mar; 7(9):9876-89. PubMed ID: 26848524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MERTK Mediates Intrinsic and Adaptive Resistance to AXL-targeting Agents.
    McDaniel NK; Cummings CT; Iida M; Hülse J; Pearson HE; Vasileiadi E; Parker RE; Orbuch RA; Ondracek OJ; Welke NB; Kang GH; Davies KD; Wang X; Frye SV; Earp HS; Harari PM; Kimple RJ; DeRyckere D; Graham DK; Wheeler DL
    Mol Cancer Ther; 2018 Nov; 17(11):2297-2308. PubMed ID: 30093568
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme.
    Sufit A; Lee-Sherick AB; DeRyckere D; Rupji M; Dwivedi B; Varella-Garcia M; Pierce AM; Kowalski J; Wang X; Frye SV; Earp HS; Keating AK; Graham DK
    PLoS One; 2016; 11(10):e0165107. PubMed ID: 27783662
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells.
    Vouri M; An Q; Birt M; Pilkington GJ; Hafizi S
    Oncotarget; 2015 Jun; 6(18):16183-97. PubMed ID: 25980499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mer Tyrosine Kinase Regulates Disseminated Prostate Cancer Cellular Dormancy.
    Cackowski FC; Eber MR; Rhee J; Decker AM; Yumoto K; Berry JE; Lee E; Shiozawa Y; Jung Y; Aguirre-Ghiso JA; Taichman RS
    J Cell Biochem; 2017 Apr; 118(4):891-902. PubMed ID: 27753136
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.
    Branchford BR; Stalker TJ; Law L; Acevedo G; Sather S; Brzezinski C; Wilson KM; Minson K; Lee-Sherick AB; Davizon-Castillo P; Ng C; Zhang W; Neeves KB; Lentz SR; Wang X; Frye SV; Shelton Earp H; DeRyckere D; Brass LF; Graham DK; Di Paola JA
    J Thromb Haemost; 2018 Feb; 16(2):352-363. PubMed ID: 29045015
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status.
    Cummings CT; Zhang W; Davies KD; Kirkpatrick GD; Zhang D; DeRyckere D; Wang X; Frye SV; Earp HS; Graham DK
    Mol Cancer Ther; 2015 Sep; 14(9):2014-22. PubMed ID: 26162689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.
    Keating AK; Kim GK; Jones AE; Donson AM; Ware K; Mulcahy JM; Salzberg DB; Foreman NK; Liang X; Thorburn A; Graham DK
    Mol Cancer Ther; 2010 May; 9(5):1298-307. PubMed ID: 20423999
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells.
    Al Kafri N; Hafizi S
    Biomolecules; 2020 Jul; 10(7):. PubMed ID: 32664510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology.
    Rogers AE; Le JP; Sather S; Pernu BM; Graham DK; Pierce AM; Keating AK
    Oncogene; 2012 Sep; 31(38):4171-81. PubMed ID: 22179835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular pathways: MERTK signaling in cancer.
    Cummings CT; Deryckere D; Earp HS; Graham DK
    Clin Cancer Res; 2013 Oct; 19(19):5275-80. PubMed ID: 23833304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme.
    Wang Y; Moncayo G; Morin P; Xue G; Grzmil M; Lino MM; Clément-Schatlo V; Frank S; Merlo A; Hemmings BA
    Oncogene; 2013 Feb; 32(7):872-82. PubMed ID: 22469987
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors.
    Linger RM; Keating AK; Earp HS; Graham DK
    Expert Opin Ther Targets; 2010 Oct; 14(10):1073-90. PubMed ID: 20809868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL.
    Tworkoski KA; Platt JT; Bacchiocchi A; Bosenberg M; Boggon TJ; Stern DF
    Pigment Cell Melanoma Res; 2013 Jul; 26(4):527-41. PubMed ID: 23617806
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation.
    Zhou J; Yang A; Wang Y; Chen F; Zhao Z; Davra V; Suzuki-Inoue K; Ozaki Y; Birge RB; Lu Q; Wu Y
    Cell Commun Signal; 2018 Dec; 16(1):98. PubMed ID: 30541554
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks.
    Kataoka Y; Mukohara T; Tomioka H; Funakoshi Y; Kiyota N; Fujiwara Y; Yashiro M; Hirakawa K; Hirai M; Minami H
    Invest New Drugs; 2012 Aug; 30(4):1352-60. PubMed ID: 21655918
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Foretinib induces G2/M cell cycle arrest, apoptosis, and invasion in human glioblastoma cells through c-MET inhibition.
    Gortany NK; Panahi G; Ghafari H; Shekari M; Ghazi-Khansari M
    Cancer Chemother Pharmacol; 2021 Jun; 87(6):827-842. PubMed ID: 33688998
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.
    Lokker NA; Sullivan CM; Hollenbach SJ; Israel MA; Giese NA
    Cancer Res; 2002 Jul; 62(13):3729-35. PubMed ID: 12097282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer.
    Uribe DJ; Mandell EK; Watson A; Martinez JD; Leighton JA; Ghosh S; Rothlin CV
    PLoS One; 2017; 12(7):e0179979. PubMed ID: 28727830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.