BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

288 related articles for article (PubMed ID: 24662824)

  • 1. The E3 ubiquitin ligase NEDD4 negatively regulates HER3/ErbB3 level and signaling.
    Huang Z; Choi BK; Mujoo K; Fan X; Fa M; Mukherjee S; Owiti N; Zhang N; An Z
    Oncogene; 2015 Feb; 34(9):1105-15. PubMed ID: 24662824
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK.
    Lin Q; Wang J; Childress C; Sudol M; Carey DJ; Yang W
    Mol Cell Biol; 2010 Mar; 30(6):1541-54. PubMed ID: 20086093
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis.
    Verma N; Müller AK; Kothari C; Panayotopoulou E; Kedan A; Selitrennik M; Mills GB; Nguyen LK; Shin S; Karn T; Holtrich U; Lev S
    Cancer Res; 2017 Jan; 77(1):86-99. PubMed ID: 27793840
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of Nedd4-1 WW domains in binding and regulating human organic anion transporter 1.
    Xu D; Wang H; Gardner C; Pan Z; Zhang PL; Zhang J; You G
    Am J Physiol Renal Physiol; 2016 Aug; 311(2):F320-9. PubMed ID: 27226107
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.
    Aleidi SM; Howe V; Sharpe LJ; Yang A; Rao G; Brown AJ; Gelissen IC
    J Biol Chem; 2015 Oct; 290(40):24604-13. PubMed ID: 26296893
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.
    Edwin F; Anderson K; Patel TB
    J Biol Chem; 2010 Jan; 285(1):255-64. PubMed ID: 19864419
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1.
    Xu D; Wang H; Zhang Q; You G
    Am J Physiol Renal Physiol; 2016 May; 310(9):F821-31. PubMed ID: 26823285
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition.
    Wang J; Peng Q; Lin Q; Childress C; Carey D; Yang W
    J Biol Chem; 2010 Apr; 285(16):12279-88. PubMed ID: 20172859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Type I γ Phosphatidylinositol Phosphate 5-Kinase i5 Controls the Ubiquitination and Degradation of the Tumor Suppressor Mitogen-inducible Gene 6.
    Sun M; Cai J; Anderson RA; Sun Y
    J Biol Chem; 2016 Oct; 291(41):21461-21473. PubMed ID: 27557663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN.
    Hong SW; Moon JH; Kim JS; Shin JS; Jung KA; Lee WK; Jeong SY; Hwang JJ; Lee SJ; Suh YA; Kim I; Nam KY; Han S; Kim JE; Kim KP; Hong YS; Lee JL; Lee WJ; Choi EK; Lee JS; Jin DH; Kim TW
    Cell Death Differ; 2014 Jan; 21(1):146-60. PubMed ID: 24141722
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HER3/ErbB3, an emerging cancer therapeutic target.
    Zhang N; Chang Y; Rios A; An Z
    Acta Biochim Biophys Sin (Shanghai); 2016 Jan; 48(1):39-48. PubMed ID: 26496898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nedd4 is a specific E3 ubiquitin ligase for the NMDA receptor subunit GluN2D.
    Gautam V; Trinidad JC; Rimerman RA; Costa BM; Burlingame AL; Monaghan DT
    Neuropharmacology; 2013 Nov; 74():96-107. PubMed ID: 23639431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C.
    Conkright JJ; Apsley KS; Martin EP; Ridsdale R; Rice WR; Na CL; Yang B; Weaver TE
    Am J Respir Cell Mol Biol; 2010 Feb; 42(2):181-9. PubMed ID: 19423771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3.
    Chesarino NM; McMichael TM; Yount JS
    PLoS Pathog; 2015 Aug; 11(8):e1005095. PubMed ID: 26263374
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of Itch and Nedd4 E3 Ligase Activity and Degradation by LRAD3.
    Noyes NC; Hampton B; Migliorini M; Strickland DK
    Biochemistry; 2016 Mar; 55(8):1204-13. PubMed ID: 26854353
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation.
    Aronchik I; Kundu A; Quirit JG; Firestone GL
    Mol Cancer Res; 2014 Nov; 12(11):1621-1634. PubMed ID: 25009292
    [TBL] [Abstract][Full Text] [Related]  

  • 18. E3 ubiquitin ligase neural precursor cell-expressed developmentally downregulated gene 4 motivates FOXA1 ubiquitination and restrains proliferation of diffuse large B-cell lymphoma cells via the Wnt/β-Catenin pathway.
    Yang L; Li JN
    Cell Biol Int; 2023 Oct; 47(10):1688-1701. PubMed ID: 37415495
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle.
    D'Cruz R; Plant PJ; Pablo LA; Lin S; Chackowicz J; Correa J; Bain J; Batt J
    Biochem J; 2016 Feb; 473(3):267-76. PubMed ID: 26556890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impeded Nedd4-1-mediated Ras degradation underlies Ras-driven tumorigenesis.
    Zeng T; Wang Q; Fu J; Lin Q; Bi J; Ding W; Qiao Y; Zhang S; Zhao W; Lin H; Wang M; Lu B; Deng X; Zhou D; Yin Z; Wang HR
    Cell Rep; 2014 May; 7(3):871-82. PubMed ID: 24746824
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.