BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 24664955)

  • 1. A phase I trial of MK-2206 in children with refractory malignancies: a Children's Oncology Group study.
    Fouladi M; Perentesis JP; Phillips CL; Leary S; Reid JM; McGovern RM; Ingle AM; Ahern CH; Ames MM; Houghton P; Doyle LA; Weigel B; Blaney SM
    Pediatr Blood Cancer; 2014 Jul; 61(7):1246-51. PubMed ID: 24664955
    [TBL] [Abstract][Full Text] [Related]  

  • 2. First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors.
    Yap TA; Yan L; Patnaik A; Fearen I; Olmos D; Papadopoulos K; Baird RD; Delgado L; Taylor A; Lupinacci L; Riisnaes R; Pope LL; Heaton SP; Thomas G; Garrett MD; Sullivan DM; de Bono JS; Tolcher AW
    J Clin Oncol; 2011 Dec; 29(35):4688-95. PubMed ID: 22025163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interrogating two schedules of the AKT inhibitor MK-2206 in patients with advanced solid tumors incorporating novel pharmacodynamic and functional imaging biomarkers.
    Yap TA; Yan L; Patnaik A; Tunariu N; Biondo A; Fearen I; Papadopoulos KP; Olmos D; Baird R; Delgado L; Tetteh E; Beckman RA; Lupinacci L; Riisnaes R; Decordova S; Heaton SP; Swales K; deSouza NM; Leach MO; Garrett MD; Sullivan DM; de Bono JS; Tolcher AW
    Clin Cancer Res; 2014 Nov; 20(22):5672-85. PubMed ID: 25239610
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A phase 1 study of prexasertib (LY2606368), a CHK1/2 inhibitor, in pediatric patients with recurrent or refractory solid tumors, including CNS tumors: A report from the Children's Oncology Group Pediatric Early Phase Clinical Trials Network (ADVL1515).
    Cash T; Fox E; Liu X; Minard CG; Reid JM; Scheck AC; Weigel BJ; Wetmore C
    Pediatr Blood Cancer; 2021 Sep; 68(9):e29065. PubMed ID: 33881209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study.
    Fouladi M; Stewart CF; Olson J; Wagner LM; Onar-Thomas A; Kocak M; Packer RJ; Goldman S; Gururangan S; Gajjar A; Demuth T; Kun LE; Boyett JM; Gilbertson RJ
    J Clin Oncol; 2011 Sep; 29(26):3529-34. PubMed ID: 21825264
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors.
    Hudis C; Swanton C; Janjigian YY; Lee R; Sutherland S; Lehman R; Chandarlapaty S; Hamilton N; Gajria D; Knowles J; Shah J; Shannon K; Tetteh E; Sullivan DM; Moreno C; Yan L; Han HS
    Breast Cancer Res; 2013 Nov; 15(6):R110. PubMed ID: 24252402
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study.
    Hummel TR; Wagner L; Ahern C; Fouladi M; Reid JM; McGovern RM; Ames MM; Gilbertson RJ; Horton T; Ingle AM; Weigel B; Blaney SM
    Pediatr Blood Cancer; 2013 Sep; 60(9):1452-7. PubMed ID: 23554030
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors.
    Spunt SL; Grupp SA; Vik TA; Santana VM; Greenblatt DJ; Clancy J; Berkenblit A; Krygowski M; Ananthakrishnan R; Boni JP; Gilbertson RJ
    J Clin Oncol; 2011 Jul; 29(21):2933-40. PubMed ID: 21690471
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study.
    Mossé YP; Lim MS; Voss SD; Wilner K; Ruffner K; Laliberte J; Rolland D; Balis FM; Maris JM; Weigel BJ; Ingle AM; Ahern C; Adamson PC; Blaney SM
    Lancet Oncol; 2013 May; 14(6):472-80. PubMed ID: 23598171
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A study of axitinib, a VEGF receptor tyrosine kinase inhibitor, in children and adolescents with recurrent or refractory solid tumors: A Children's Oncology Group phase 1 and pilot consortium trial (ADVL1315).
    Geller JI; Fox E; Turpin BK; Goldstein SL; Liu X; Minard CG; Kudgus RA; Reid JM; Berg SL; Weigel BJ
    Cancer; 2018 Dec; 124(23):4548-4555. PubMed ID: 30394521
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A phase 1 study of entinostat in children and adolescents with recurrent or refractory solid tumors, including CNS tumors: Trial ADVL1513, Pediatric Early Phase-Clinical Trial Network (PEP-CTN).
    Bukowinski A; Chang B; Reid JM; Liu X; Minard CG; Trepel JB; Lee MJ; Fox E; Weigel BJ
    Pediatr Blood Cancer; 2021 Apr; 68(4):e28892. PubMed ID: 33438318
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A phase 1 study of eribulin mesylate (E7389), a novel microtubule-targeting chemotherapeutic agent, in children with refractory or recurrent solid tumors: A Children's Oncology Group Phase 1 Consortium study (ADVL1314).
    Schafer ES; Rau RE; Berg S; Liu X; Minard CG; D'Adamo D; Scott R; Reyderman L; Martinez G; Devarajan S; Reid JM; Fox E; Weigel BJ; Blaney SM
    Pediatr Blood Cancer; 2018 Aug; 65(8):e27066. PubMed ID: 29719113
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study.
    Hoffman LM; Fouladi M; Olson J; Daryani VM; Stewart CF; Wetmore C; Kocak M; Onar-Thomas A; Wagner L; Gururangan S; Packer RJ; Blaney SM; Gajjar A; Kun LE; Boyett JM; Gilbertson RJ
    Childs Nerv Syst; 2015 Aug; 31(8):1283-9. PubMed ID: 25930724
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phase 1 pharmacokinetic study of the oral pan-AKT inhibitor MK-2206 in Japanese patients with advanced solid tumors.
    Doi T; Tamura K; Tanabe Y; Yonemori K; Yoshino T; Fuse N; Kodaira M; Bando H; Noguchi K; Shimamoto T; Ohtsu A
    Cancer Chemother Pharmacol; 2015 Aug; 76(2):409-16. PubMed ID: 26104654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A phase I trial of MK-2206 and hydroxychloroquine in patients with advanced solid tumors.
    Mehnert JM; Kaveney AD; Malhotra J; Spencer K; Portal D; Goodin S; Tan AR; Aisner J; Moss RA; Lin H; Bertino JR; Gibbon D; Doyle LA; White EP; Stein MN
    Cancer Chemother Pharmacol; 2019 Oct; 84(4):899-907. PubMed ID: 31463691
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A phase 1 study of cabozantinib in children and adolescents with recurrent or refractory solid tumors, including CNS tumors: Trial ADVL1211, a report from the Children's Oncology Group.
    Chuk MK; Widemann BC; Minard CG; Liu X; Kim A; Bernhardt MB; Kudgus RA; Reid JM; Voss SD; Blaney S; Fox E; Weigel BJ
    Pediatr Blood Cancer; 2018 Aug; 65(8):e27077. PubMed ID: 29693796
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A phase I trial of vorinostat and bortezomib in children with refractory or recurrent solid tumors: a Children's Oncology Group phase I consortium study (ADVL0916).
    Muscal JA; Thompson PA; Horton TM; Ingle AM; Ahern CH; McGovern RM; Reid JM; Ames MM; Espinoza-Delgado I; Weigel BJ; Blaney SM
    Pediatr Blood Cancer; 2013 Mar; 60(3):390-5. PubMed ID: 22887890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor activity in RAS-driven tumors by blocking AKT and MEK.
    Tolcher AW; Khan K; Ong M; Banerji U; Papadimitrakopoulou V; Gandara DR; Patnaik A; Baird RD; Olmos D; Garrett CR; Skolnik JM; Rubin EH; Smith PD; Huang P; Learoyd M; Shannon KA; Morosky A; Tetteh E; Jou YM; Papadopoulos KP; Moreno V; Kaiser B; Yap TA; Yan L; de Bono JS
    Clin Cancer Res; 2015 Feb; 21(4):739-48. PubMed ID: 25516890
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phase I, open-label, multicentre, dose-escalation, pharmacokinetic and pharmacodynamic trial of the oral aurora kinase inhibitor PF-03814735 in advanced solid tumours.
    Schöffski P; Jones SF; Dumez H; Infante JR; Van Mieghem E; Fowst C; Gerletti P; Xu H; Jakubczak JL; English PA; Pierce KJ; Burris HA
    Eur J Cancer; 2011 Oct; 47(15):2256-64. PubMed ID: 21852114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Phase I Trial of Combined Ridaforolimus and MK-2206 in Patients with Advanced Malignancies.
    Gupta S; Argilés G; Munster PN; Hollebecque A; Dajani O; Cheng JD; Wang R; Swift A; Tosolini A; Piha-Paul SA
    Clin Cancer Res; 2015 Dec; 21(23):5235-44. PubMed ID: 26187616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.