BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

619 related articles for article (PubMed ID: 24664998)

  • 1. Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin.
    Vance JE; Karten B
    J Lipid Res; 2014 Aug; 55(8):1609-21. PubMed ID: 24664998
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo.
    Goldman SD; Krise JP
    J Biol Chem; 2010 Feb; 285(7):4983-94. PubMed ID: 20007703
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells.
    Abi-Mosleh L; Infante RE; Radhakrishnan A; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 2009 Nov; 106(46):19316-21. PubMed ID: 19884502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
    Boadu E; Nelson RC; Francis GA
    Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Function of the Niemann-Pick type C proteins and their bypass by cyclodextrin.
    Vance JE; Peake KB
    Curr Opin Lipidol; 2011 Jun; 22(3):204-9. PubMed ID: 21412152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells.
    Ebrahimi-Fakhari D; Wahlster L; Bartz F; Werenbeck-Ueding J; Praggastis M; Zhang J; Joggerst-Thomalla B; Theiss S; Grimm D; Ory DS; Runz H
    Hum Mol Genet; 2016 Aug; 25(16):3588-3599. PubMed ID: 27378690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Abnormal accumulation and recycling of glycoproteins visualized in Niemann-Pick type C cells using the chemical reporter strategy.
    Mbua NE; Flanagan-Steet H; Johnson S; Wolfert MA; Boons GJ; Steet R
    Proc Natl Acad Sci U S A; 2013 Jun; 110(25):10207-12. PubMed ID: 23733943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells.
    Rosenbaum AI; Zhang G; Warren JD; Maxfield FR
    Proc Natl Acad Sci U S A; 2010 Mar; 107(12):5477-82. PubMed ID: 20212119
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches.
    Rosenbaum AI; Maxfield FR
    J Neurochem; 2011 Mar; 116(5):789-95. PubMed ID: 20807315
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered vitamin E status in Niemann-Pick type C disease.
    Ulatowski L; Parker R; Davidson C; Yanjanin N; Kelley TJ; Corey D; Atkinson J; Porter F; Arai H; Walkley SU; Manor D
    J Lipid Res; 2011 Jul; 52(7):1400-10. PubMed ID: 21550990
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice.
    Peake KB; Vance JE
    J Biol Chem; 2012 Mar; 287(12):9290-8. PubMed ID: 22277650
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
    Singhal A; Szente L; Hildreth JEK; Song B
    Cell Death Dis; 2018 Oct; 9(10):1019. PubMed ID: 30282967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
    Newton J; Palladino END; Weigel C; Maceyka M; Gräler MH; Senkal CE; Enriz RD; Marvanova P; Jampilek J; Lima S; Milstien S; Spiegel S
    J Biol Chem; 2020 Jul; 295(27):9121-9133. PubMed ID: 32385114
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Niemann-Pick Disease Type C: from molecule to clinic.
    Tang Y; Li H; Liu JP
    Clin Exp Pharmacol Physiol; 2010 Jan; 37(1):132-40. PubMed ID: 19566836
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells.
    Pipalia NH; Subramanian K; Mao S; Ralph H; Hutt DM; Scott SM; Balch WE; Maxfield FR
    J Lipid Res; 2017 Apr; 58(4):695-708. PubMed ID: 28193631
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C disease.
    Chen J; Soni RK; Xu Y; Simoes S; Liang FX; DeFreitas L; Hwang R; Montesinos J; Lee JH; Area-Gomez E; Nandakumar R; Vardarajan B; Marquer C
    EBioMedicine; 2023 Jun; 92():104628. PubMed ID: 37245481
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular dynamics study with mutation shows that N-terminal domain structural re-orientation in Niemann-Pick type C1 is required for proper alignment of cholesterol transport.
    Yoon HJ; Jeong H; Lee HH; Jang S
    J Neurochem; 2021 Mar; 156(6):967-978. PubMed ID: 32880929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice.
    Ashikawa H; Mogi H; Honda T; Nakamura H; Murayama T
    Eur J Pharmacol; 2021 Apr; 896():173907. PubMed ID: 33503462
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes.
    Pfeffer SR
    J Biol Chem; 2019 Feb; 294(5):1706-1709. PubMed ID: 30710017
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.
    Yañez MJ; Marín T; Balboa E; Klein AD; Alvarez AR; Zanlungo S
    Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165875. PubMed ID: 32522631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.