BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 24667739)

  • 1. Rescue of the Friedreich ataxia knockout mutation in transgenic mice containing an FXN-EGFP genomic reporter.
    Sarsero JP; Holloway TP; Li L; Finkelstein DI; Ioannou PA
    PLoS One; 2014; 9(3):e93307. PubMed ID: 24667739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological screening using an FXN-EGFP cellular genomic reporter assay for the therapy of Friedreich ataxia.
    Li L; Voullaire L; Sandi C; Pook MA; Ioannou PA; Delatycki MB; Sarsero JP
    PLoS One; 2013; 8(2):e55940. PubMed ID: 23418481
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of an FRDA-EGFP genomic reporter assay in transgenic mice.
    Sarsero JP; Holloway TP; Li L; McLenachan S; Fowler KJ; Bertoncello I; Voullaire L; Gazeas S; Ioannou PA
    Mamm Genome; 2005 Apr; 16(4):228-41. PubMed ID: 15965784
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds.
    Lufino MM; Silva AM; Németh AH; Alegre-Abarrategui J; Russell AJ; Wade-Martins R
    Hum Mol Genet; 2013 Dec; 22(25):5173-87. PubMed ID: 23943791
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology.
    Al-Mahdawi S; Pinto RM; Varshney D; Lawrence L; Lowrie MB; Hughes S; Webster Z; Blake J; Cooper JM; King R; Pook MA
    Genomics; 2006 Nov; 88(5):580-90. PubMed ID: 16919418
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human BAC-mediated rescue of the Friedreich ataxia knockout mutation in transgenic mice.
    Sarsero JP; Li L; Holloway TP; Voullaire L; Gazeas S; Fowler KJ; Kirby DM; Thorburn DR; Galle A; Cheema S; Koenig M; Williamson R; Ioannou PA
    Mamm Genome; 2004 May; 15(5):370-82. PubMed ID: 15170226
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia.
    Soragni E; Herman D; Dent SY; Gottesfeld JM; Wells RD; Napierala M
    Nucleic Acids Res; 2008 Nov; 36(19):6056-65. PubMed ID: 18820300
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations.
    Medina-Carbonero M; Sanz-Alcázar A; Britti E; Delaspre F; Cabiscol E; Ros J; Tamarit J
    Cell Mol Life Sci; 2022 Jan; 79(2):74. PubMed ID: 35038030
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Upregulation of expression from the FRDA genomic locus for the therapy of Friedreich ataxia.
    Sarsero JP; Li L; Wardan H; Sitte K; Williamson R; Ioannou PA
    J Gene Med; 2003 Jan; 5(1):72-81. PubMed ID: 12516053
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin.
    Fil D; Conley RL; Zuberi AR; Lutz CM; Gemelli T; Napierala M; Napierala JS
    Neurobiol Dis; 2023 Feb; 177():105996. PubMed ID: 36638893
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues.
    Al-Mahdawi S; Pinto RM; Ismail O; Varshney D; Lymperi S; Sandi C; Trabzuni D; Pook M
    Hum Mol Genet; 2008 Mar; 17(5):735-46. PubMed ID: 18045775
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia.
    Anjomani Virmouni S; Ezzatizadeh V; Sandi C; Sandi M; Al-Mahdawi S; Chutake Y; Pook MA
    Dis Model Mech; 2015 Mar; 8(3):225-35. PubMed ID: 25681319
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel deletion-insertion mutation identified in exon 3 of FXN in two siblings with a severe Friedreich ataxia phenotype.
    Evans-Galea MV; Corben LA; Hasell J; Galea CA; Fahey MC; du Sart D; Delatycki MB
    Neurogenetics; 2011 Nov; 12(4):307-13. PubMed ID: 21830088
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Long range regulation of human FXN gene expression.
    Puspasari N; Rowley SM; Gordon L; Lockhart PJ; Ioannou PA; Delatycki MB; Sarsero JP
    PLoS One; 2011; 6(7):e22001. PubMed ID: 21760943
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia.
    Anjomani Virmouni S; Sandi C; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(9):e107416. PubMed ID: 25198290
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Missense mutations linked to friedreich ataxia have different but synergistic effects on mitochondrial frataxin isoforms.
    Li H; Gakh O; Smith DY; Ranatunga WK; Isaya G
    J Biol Chem; 2013 Feb; 288(6):4116-27. PubMed ID: 23269675
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generation of induced pluripotent stem cell lines from Friedreich ataxia patients.
    Liu J; Verma PJ; Evans-Galea MV; Delatycki MB; Michalska A; Leung J; Crombie D; Sarsero JP; Williamson R; Dottori M; Pébay A
    Stem Cell Rev Rep; 2011 Sep; 7(3):703-13. PubMed ID: 21181307
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Compound heterozygous FXN mutations and clinical outcome in friedreich ataxia.
    Galea CA; Huq A; Lockhart PJ; Tai G; Corben LA; Yiu EM; Gurrin LC; Lynch DR; Gelbard S; Durr A; Pousset F; Parkinson M; Labrum R; Giunti P; Perlman SL; Delatycki MB; Evans-Galea MV
    Ann Neurol; 2016 Mar; 79(3):485-95. PubMed ID: 26704351
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of human frataxin is regulated by transcription factors SRF and TFAP2.
    Li K; Singh A; Crooks DR; Dai X; Cong Z; Pan L; Ha D; Rouault TA
    PLoS One; 2010 Aug; 5(8):e12286. PubMed ID: 20808827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia.
    Igoillo-Esteve M; Oliveira AF; Cosentino C; Fantuzzi F; Demarez C; Toivonen S; Hu A; Chintawar S; Lopes M; Pachera N; Cai Y; Abdulkarim B; Rai M; Marselli L; Marchetti P; Tariq M; Jonas JC; Boscolo M; Pandolfo M; Eizirik DL; Cnop M
    JCI Insight; 2020 Jan; 5(2):. PubMed ID: 31877117
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.