These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 24669276)

  • 1. Noninvasive theranostic imaging of HSV1-sr39TK-NTR/GCV-CB1954 dual-prodrug therapy in metastatic lung lesions of MDA-MB-231 triple negative breast cancer in mice.
    Sekar TV; Foygel K; Ilovich O; Paulmurugan R
    Theranostics; 2014; 4(5):460-74. PubMed ID: 24669276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual-therapeutic reporter genes fusion for enhanced cancer gene therapy and imaging.
    Sekar TV; Foygel K; Willmann JK; Paulmurugan R
    Gene Ther; 2013 May; 20(5):529-37. PubMed ID: 22914496
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ultrasound-guided delivery of thymidine kinase-nitroreductase dual therapeutic genes by PEGylated-PLGA/PIE nanoparticles for enhanced triple negative breast cancer therapy.
    Devulapally R; Lee T; Barghava-Shah A; Sekar TV; Foygel K; Bachawal SV; Willmann JK; Paulmurugan R
    Nanomedicine (Lond); 2018 May; 13(9):1051-1066. PubMed ID: 29790803
    [TBL] [Abstract][Full Text] [Related]  

  • 4. STAT3/NF-κB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer.
    Kuo WY; Hwu L; Wu CY; Lee JS; Chang CW; Liu RS
    Theranostics; 2017; 7(3):647-663. PubMed ID: 28255357
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SP94-Targeted Triblock Copolymer Nanoparticle Delivers Thymidine Kinase-p53-Nitroreductase Triple Therapeutic Gene and Restores Anticancer Function against Hepatocellular Carcinoma in Vivo.
    Sukumar UK; Rajendran JCB; Gambhir SS; Massoud TF; Paulmurugan R
    ACS Appl Mater Interfaces; 2020 Mar; 12(10):11307-11319. PubMed ID: 32048820
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals.
    Bhaumik S; Sekar TV; Depuy J; Klimash J; Paulmurugan R
    Gene Ther; 2012 Mar; 19(3):295-302. PubMed ID: 21753794
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repurposing
    Ruiz de Garibay G; García de Jalón E; Stigen E; Lund KB; Popa M; Davidson B; Safont MM; Rygh CB; Espedal H; Barrett TM; Haug BE; McCormack E
    Theranostics; 2021; 11(12):6044-6057. PubMed ID: 33897898
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metabolite.
    Bridgewater JA; Knox RJ; Pitts JD; Collins MK; Springer CJ
    Hum Gene Ther; 1997 Apr; 8(6):709-17. PubMed ID: 9113510
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Theranostic Imaging of Cancer Gene Therapy.
    Sekar TV; Paulmurugan R
    Methods Mol Biol; 2016; 1461():241-54. PubMed ID: 27424910
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Advances in imaging gene-directed enzyme prodrug therapy.
    Bhaumik S
    Curr Pharm Biotechnol; 2011 Apr; 12(4):497-507. PubMed ID: 21342105
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene therapy with HSV1-sr39TK/GCV exhibits a stronger therapeutic efficacy than HSV1-TK/GCV in rat C6 glioma cells.
    Li LQ; Shen F; Xu XY; Zhang H; Yang XF; Liu WG
    ScientificWorldJournal; 2013; 2013():951343. PubMed ID: 23533367
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.
    Lukashev AN; Fuerer C; Chen MJ; Searle P; Iggo R
    Hum Gene Ther; 2005 Dec; 16(12):1473-83. PubMed ID: 16390278
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer.
    Wang HE; Yu HM; Liu RS; Lin M; Gelovani JG; Hwang JJ; Wei HJ; Deng WP
    J Nucl Med; 2006 Jul; 47(7):1161-71. PubMed ID: 16818951
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Virus-directed enzyme prodrug therapy using CB1954.
    Grove JI; Searle PF; Weedon SJ; Green NK; McNeish IA; Kerr DJ
    Anticancer Drug Des; 1999 Dec; 14(6):461-72. PubMed ID: 10834268
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954.
    Prosser GA; Copp JN; Syddall SP; Williams EM; Smaill JB; Wilson WR; Patterson AV; Ackerley DF
    Biochem Pharmacol; 2010 Mar; 79(5):678-87. PubMed ID: 19852945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.
    Searle PF; Chen MJ; Hu L; Race PR; Lovering AL; Grove JI; Guise C; Jaberipour M; James ND; Mautner V; Young LS; Kerr DJ; Mountain A; White SA; Hyde EI
    Clin Exp Pharmacol Physiol; 2004 Nov; 31(11):811-6. PubMed ID: 15566399
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and Characterization of 9-(4-[
    Fuchigami T; Haywood T; Gowrishankar G; Anders D; Namavari M; Wardak M; Gambhir SS
    Mol Imaging Biol; 2020 Oct; 22(5):1151-1160. PubMed ID: 32691392
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.
    Bridgewater JA; Springer CJ; Knox RJ; Minton NP; Michael NP; Collins MK
    Eur J Cancer; 1995 Dec; 31A(13-14):2362-70. PubMed ID: 8652270
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954.
    McNeish IA; Green NK; Gilligan MG; Ford MJ; Mautner V; Young LS; Kerr DJ; Searle PF
    Gene Ther; 1998 Aug; 5(8):1061-9. PubMed ID: 10326029
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Virus-directed, enzyme prodrug therapy with nitroimidazole reductase: a phase I and pharmacokinetic study of its prodrug, CB1954.
    Chung-Faye G; Palmer D; Anderson D; Clark J; Downes M; Baddeley J; Hussain S; Murray PI; Searle P; Seymour L; Harris PA; Ferry D; Kerr DJ
    Clin Cancer Res; 2001 Sep; 7(9):2662-8. PubMed ID: 11555577
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.