BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 24677340)

  • 21. Murine hepatic aldehyde dehydrogenase 1a1 is a major contributor to oxidation of aldehydes formed by lipid peroxidation.
    Makia NL; Bojang P; Falkner KC; Conklin DJ; Prough RA
    Chem Biol Interact; 2011 May; 191(1-3):278-87. PubMed ID: 21256123
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).
    Yang SM; Yasgar A; Miller B; Lal-Nag M; Brimacombe K; Hu X; Sun H; Wang A; Xu X; Nguyen K; Oppermann U; Ferrer M; Vasiliou V; Simeonov A; Jadhav A; Maloney DJ
    J Med Chem; 2015 Aug; 58(15):5967-78. PubMed ID: 26207746
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
    Khanna M; Chen CH; Kimble-Hill A; Parajuli B; Perez-Miller S; Baskaran S; Kim J; Dria K; Vasiliou V; Mochly-Rosen D; Hurley TD
    J Biol Chem; 2011 Dec; 286(50):43486-94. PubMed ID: 22021038
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Raloxifene and bazedoxifene as selective ALDH1A1 inhibitors to ameliorate cyclophosphamide resistance: A drug repurposing approach.
    Narendra G; Raju B; Verma H; Kumar M; Jain SK; Tung GK; Thakur S; Kaur R; Kaur S; Sapra B; Singh PK; Silakari O
    Int J Biol Macromol; 2023 Jul; 242(Pt 1):124749. PubMed ID: 37160174
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer.
    Rebollido-Rios R; Venton G; Sánchez-Redondo S; Iglesias I Felip C; Fournet G; González E; Romero Fernández W; Borroto Escuela DO; Di Stefano B; Penarroche-Díaz R; Martin G; Ceylan I; Costello R; Perez-Alea M
    Oncogene; 2020 Mar; 39(13):2756-2771. PubMed ID: 32015486
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Selective protection by stably transfected human ALDH3A1 (but not human ALDH1A1) against toxicity of aliphatic aldehydes in V79 cells.
    Townsend AJ; Leone-Kabler S; Haynes RL; Wu Y; Szweda L; Bunting KD
    Chem Biol Interact; 2001 Jan; 130-132(1-3):261-73. PubMed ID: 11306050
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
    Morgan CA; Hurley TD
    Chem Biol Interact; 2015 Jun; 234():29-37. PubMed ID: 25450233
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
    Jiménez R; Pequerul R; Amor A; Lorenzo J; Metwally K; Avilés FX; Parés X; Farrés J
    Chem Biol Interact; 2019 Jun; 306():123-130. PubMed ID: 30958995
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Enhanced expressions of glucose-6-phosphate dehydrogenase and cytosolic aldehyde dehydrogenase and elevation of reduced glutathione level in cyclophosphamide-resistant human leukemia cells.
    Tsukamoto N; Chen J; Yoshida A
    Blood Cells Mol Dis; 1998 Jun; 24(2):231-8. PubMed ID: 9714700
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Detoxification of cyclophosphamide by human aldehyde dehydrogenase isozymes.
    von Eitzen U; Meier-Tackmann D; Agarwal DP; Goedde HW
    Cancer Lett; 1994 Jan; 76(1):45-9. PubMed ID: 8124665
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines.
    Kohn FR; Sladek NE
    Biochem Pharmacol; 1985 Oct; 34(19):3465-71. PubMed ID: 2996550
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells.
    Voulgaridou GP; Kiziridou M; Mantso T; Chlichlia K; Galanis A; Koukourakis MI; Franco R; Panayiotidis MI; Pappa A
    Int J Biochem Cell Biol; 2016 Aug; 77(Pt A):120-128. PubMed ID: 27276244
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Potentiation of the cytotoxic action of mafosfamide by N-isopropyl-p-formylbenzamide, a metabolite of procarbazine.
    Maki PA; Sladek NE
    Cancer Res; 1991 Aug; 51(16):4170-5. PubMed ID: 1868438
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues.
    Rekha GK; Devaraj VR; Sreerama L; Lee MJ; Nagasawa HT; Sladek NE
    Biochem Pharmacol; 1998 Feb; 55(4):465-74. PubMed ID: 9514081
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target.
    Counihan JL; Wiggenhorn AL; Anderson KE; Nomura DK
    ACS Chem Biol; 2018 Aug; 13(8):1970-1977. PubMed ID: 30004670
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues.
    Sládek NE; Rekha GK; Lee MJ; Nagasawa HT
    Chem Biol Interact; 2001 Nov; 138(2):201-15. PubMed ID: 11672702
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
    Sullivan JP; Spinola M; Dodge M; Raso MG; Behrens C; Gao B; Schuster K; Shao C; Larsen JE; Sullivan LA; Honorio S; Xie Y; Scaglioni PP; DiMaio JM; Gazdar AF; Shay JW; Wistuba II; Minna JD
    Cancer Res; 2010 Dec; 70(23):9937-48. PubMed ID: 21118965
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of novel regulators of aldehyde dehydrogenase isoenzymes.
    Parajuli B; Kimble-Hill AC; Khanna M; Ivanova Y; Meroueh S; Hurley TD
    Chem Biol Interact; 2011 May; 191(1-3):153-8. PubMed ID: 21349255
    [TBL] [Abstract][Full Text] [Related]  

  • 39. RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide.
    Moreb JS; Mohuczy D; Ostmark B; Zucali JR
    Cancer Chemother Pharmacol; 2007 Jan; 59(1):127-36. PubMed ID: 16614850
    [TBL] [Abstract][Full Text] [Related]  

  • 40. In vitro organic nitrate bioactivation to nitric oxide by recombinant aldehyde dehydrogenase 3A1.
    Lin S; Page NA; Fung SM; Fung HL
    Nitric Oxide; 2013 Nov; 35():137-43. PubMed ID: 24126018
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.