320 related articles for article (PubMed ID: 24677446)
1. Structure and function of LGR5: an enigmatic G-protein coupled receptor marking stem cells.
Kumar KK; Burgess AW; Gulbis JM
Protein Sci; 2014 May; 23(5):551-65. PubMed ID: 24677446
[TBL] [Abstract][Full Text] [Related]
2. R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
Ruffner H; Sprunger J; Charlat O; Leighton-Davies J; Grosshans B; Salathe A; Zietzling S; Beck V; Therier M; Isken A; Xie Y; Zhang Y; Hao H; Shi X; Liu D; Song Q; Clay I; Hintzen G; Tchorz J; Bouchez LC; Michaud G; Finan P; Myer VE; Bouwmeester T; Porter J; Hild M; Bassilana F; Parker CN; Cong F
PLoS One; 2012; 7(7):e40976. PubMed ID: 22815884
[TBL] [Abstract][Full Text] [Related]
3. LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.
Carmon KS; Gong X; Yi J; Wu L; Thomas A; Moore CM; Masuho I; Timson DJ; Martemyanov KA; Liu QJ
J Biol Chem; 2017 Sep; 292(36):14989-15001. PubMed ID: 28739799
[TBL] [Abstract][Full Text] [Related]
4. Non-equivalence of Wnt and R-spondin ligands during Lgr5
Yan KS; Janda CY; Chang J; Zheng GXY; Larkin KA; Luca VC; Chia LA; Mah AT; Han A; Terry JM; Ootani A; Roelf K; Lee M; Yuan J; Li X; Bolen CR; Wilhelmy J; Davies PS; Ueno H; von Furstenberg RJ; Belgrader P; Ziraldo SB; Ordonez H; Henning SJ; Wong MH; Snyder MP; Weissman IL; Hsueh AJ; Mikkelsen TS; Garcia KC; Kuo CJ
Nature; 2017 May; 545(7653):238-242. PubMed ID: 28467820
[TBL] [Abstract][Full Text] [Related]
5. Structural basis for R-spondin recognition by LGR4/5/6 receptors.
Wang D; Huang B; Zhang S; Yu X; Wu W; Wang X
Genes Dev; 2013 Jun; 27(12):1339-44. PubMed ID: 23756652
[TBL] [Abstract][Full Text] [Related]
6. Leucine-rich repeat-containing G-protein coupled receptor 5/GPR49 activates G12/13-Rho GTPase pathway.
Kwon MS; Park BO; Kim HM; Kim S
Mol Cells; 2013 Sep; 36(3):267-72. PubMed ID: 23912594
[TBL] [Abstract][Full Text] [Related]
7. Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.
Peng WC; de Lau W; Forneris F; Granneman JC; Huch M; Clevers H; Gros P
Cell Rep; 2013 Jun; 3(6):1885-92. PubMed ID: 23809763
[TBL] [Abstract][Full Text] [Related]
8. R-Spondin1/LGR5 Activates TGFβ Signaling and Suppresses Colon Cancer Metastasis.
Zhou X; Geng L; Wang D; Yi H; Talmon G; Wang J
Cancer Res; 2017 Dec; 77(23):6589-6602. PubMed ID: 28939678
[TBL] [Abstract][Full Text] [Related]
9. The structural basis of R-spondin recognition by LGR5 and RNF43.
Chen PH; Chen X; Lin Z; Fang D; He X
Genes Dev; 2013 Jun; 27(12):1345-50. PubMed ID: 23756651
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).
Xu JG; Huang C; Yang Z; Jin M; Fu P; Zhang N; Luo J; Li D; Liu M; Zhou Y; Zhu Y
J Biol Chem; 2015 Jan; 290(4):2455-65. PubMed ID: 25480784
[TBL] [Abstract][Full Text] [Related]
11. R-spondins: Multi-mode WNT signaling regulators in adult stem cells.
Raslan AA; Yoon JK
Int J Biochem Cell Biol; 2019 Jan; 106():26-34. PubMed ID: 30439551
[TBL] [Abstract][Full Text] [Related]
12. LGR5 constitutively activates NF-κB signaling to regulate the growth of intestinal crypts.
Lai S; Cheng R; Gao D; Chen YG; Deng C
FASEB J; 2020 Nov; 34(11):15605-15620. PubMed ID: 33001511
[TBL] [Abstract][Full Text] [Related]
13. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.
Huch M; Dorrell C; Boj SF; van Es JH; Li VS; van de Wetering M; Sato T; Hamer K; Sasaki N; Finegold MJ; Haft A; Vries RG; Grompe M; Clevers H
Nature; 2013 Feb; 494(7436):247-50. PubMed ID: 23354049
[TBL] [Abstract][Full Text] [Related]
14. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.
Carmon KS; Gong X; Yi J; Thomas A; Liu Q
Proc Natl Acad Sci U S A; 2014 Apr; 111(13):E1221-9. PubMed ID: 24639526
[TBL] [Abstract][Full Text] [Related]
15. Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.
Sasaki N; Sachs N; Wiebrands K; Ellenbroek SI; Fumagalli A; Lyubimova A; Begthel H; van den Born M; van Es JH; Karthaus WR; Li VS; López-Iglesias C; Peters PJ; van Rheenen J; van Oudenaarden A; Clevers H
Proc Natl Acad Sci U S A; 2016 Sep; 113(37):E5399-407. PubMed ID: 27573849
[TBL] [Abstract][Full Text] [Related]
16. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
de Lau W; Peng WC; Gros P; Clevers H
Genes Dev; 2014 Feb; 28(4):305-16. PubMed ID: 24532711
[TBL] [Abstract][Full Text] [Related]
17. LGR5 is associated with tumor aggressiveness in papillary thyroid cancer.
Michelotti G; Jiang X; Sosa JA; Diehl AM; Henderson BB
Oncotarget; 2015 Oct; 6(33):34549-60. PubMed ID: 26416247
[TBL] [Abstract][Full Text] [Related]
18. Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines.
Alharbi SA; Ovchinnikov DA; Wolvetang E
World J Gastroenterol; 2021 Apr; 27(15):1578-1594. PubMed ID: 33958845
[TBL] [Abstract][Full Text] [Related]
19. Crystal structures of Lgr4 and its complex with R-spondin1.
Xu K; Xu Y; Rajashankar KR; Robev D; Nikolov DB
Structure; 2013 Sep; 21(9):1683-9. PubMed ID: 23891289
[TBL] [Abstract][Full Text] [Related]
20. Exploiting the Receptor-Binding Domains of R-Spondin 1 to Target Leucine-Rich Repeat-Containin G-Coupled Protein Receptor 5-Expressing Stem Cells in Ovarian Cancer.
Wong C; Mulero MC; Barth EI; Wang K; Shang X; Tikle S; Rice C; Gately D; Howell SB
J Pharmacol Exp Ther; 2023 May; 385(2):95-105. PubMed ID: 36849411
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
