These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 24678849)

  • 1. Nonracemic synthesis of GK-GKRP disruptor AMG-3969.
    Bourbeau MP; Ashton KS; Yan J; St Jean DJ
    J Org Chem; 2014 Apr; 79(8):3684-7. PubMed ID: 24678849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
    St Jean DJ; Ashton KS; Bartberger MD; Chen J; Chmait S; Cupples R; Galbreath E; Helmering J; Hong FT; Jordan SR; Liu L; Kunz RK; Michelsen K; Nishimura N; Pennington LD; Poon SF; Reid D; Sivits G; Stec MM; Tadesse S; Tamayo N; Van G; Yang KC; Zhang J; Norman MH; Fotsch C; Lloyd DJ; Hale C
    J Med Chem; 2014 Jan; 57(2):325-38. PubMed ID: 24405213
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 4. Exploration of a novel binding pocket.
    Hong FT; Norman MH; Ashton KS; Bartberger MD; Chen J; Chmait S; Cupples R; Fotsch C; Jordan SR; Lloyd DJ; Sivits G; Tadesse S; Hale C; St Jean DJ
    J Med Chem; 2014 Jul; 57(14):5949-64. PubMed ID: 25001129
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
    Lloyd DJ; St Jean DJ; Kurzeja RJ; Wahl RC; Michelsen K; Cupples R; Chen M; Wu J; Sivits G; Helmering J; Komorowski R; Ashton KS; Pennington LD; Fotsch C; Vazir M; Chen K; Chmait S; Zhang J; Liu L; Norman MH; Andrews KL; Bartberger MD; Van G; Galbreath EJ; Vonderfecht SL; Wang M; Jordan SR; VĂ©niant MM; Hale C
    Nature; 2013 Dec; 504(7480):437-40. PubMed ID: 24226772
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-concept.
    Ashton KS; Andrews KL; Bryan MC; Chen J; Chen K; Chen M; Chmait S; Croghan M; Cupples R; Fotsch C; Helmering J; Jordan SR; Kurzeja RJ; Michelsen K; Pennington LD; Poon SF; Sivits G; Van G; Vonderfecht SL; Wahl RC; Zhang J; Lloyd DJ; Hale C; St Jean DJ
    J Med Chem; 2014 Jan; 57(2):309-24. PubMed ID: 24405172
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series.
    Nishimura N; Norman MH; Liu L; Yang KC; Ashton KS; Bartberger MD; Chmait S; Chen J; Cupples R; Fotsch C; Helmering J; Jordan SR; Kunz RK; Pennington LD; Poon SF; Siegmund A; Sivits G; Lloyd DJ; Hale C; St Jean DJ
    J Med Chem; 2014 Apr; 57(7):3094-116. PubMed ID: 24611879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and application of a new fluorous-tagged ammonia equivalent.
    Nielsen SD; Smith G; Begtrup M; Kristensen JL
    Chemistry; 2010 Apr; 16(15):4557-66. PubMed ID: 20333716
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Synthesis of Alkyl and (Hetero)aryl Sulfonamides From Sulfamoyl Inner Salts.
    Young JM; Lee AG; Chandrasekaran RY; Tucker JW
    J Org Chem; 2015 Aug; 80(16):8417-23. PubMed ID: 26172089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A new strategy for the synthesis of benzylic sulfonamides: palladium-catalyzed arylation and sulfonamide metathesis.
    Grimm JB; Katcher MH; Witter DJ; Northrup AB
    J Org Chem; 2007 Oct; 72(21):8135-8. PubMed ID: 17880242
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modular, gold-catalyzed approach to the synthesis of lead-like piperazine scaffolds.
    James T; Simpson I; Grant JA; Sridharan V; Nelson A
    Org Lett; 2013 Dec; 15(23):6094-7. PubMed ID: 24219794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Organocatalytic, Enantioselective Synthesis of 1- and 3-Substituted Isochromans via Intramolecular Oxa-Michael Reaction of Alkoxyboronate: Synthesis of (+)-Sonepiprazole.
    Raveendra B; Maity S; Das BG; Ghorai P
    J Org Chem; 2015 Jul; 80(14):7008-18. PubMed ID: 26102523
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Synthesis of several 2-piperazinylpyridinic derivatives (Sulfonated derivatives)].
    Thunus L
    Ann Pharm Fr; 1974 Jun; 32(6):376-82. PubMed ID: 4433139
    [No Abstract]   [Full Text] [Related]  

  • 13. Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as gamma-secretase inhibitors.
    Guo T; Gu H; Hobbs DW; Rokosz LL; Stauffer TM; Jacob B; Clader JW
    Bioorg Med Chem Lett; 2007 Jun; 17(11):3010-3. PubMed ID: 17418571
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Annulation of primary amines to piperazines and diazaspirocycles utilizing alpha-methyl benzyl resin.
    Macleod C; Martinez-Teipel BI; Barker WM; Dolle RE
    J Comb Chem; 2006; 8(1):132-40. PubMed ID: 16398564
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Complete regioselective addition of grignard reagents to pyrazine N-oxides, toward an efficient enantioselective synthesis of substituted piperazines.
    Andersson H; Banchelin TS; Das S; Gustafsson M; Olsson R; Almqvist F
    Org Lett; 2010 Jan; 12(2):284-6. PubMed ID: 20000607
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Asymmetric synthesis of sulfinamides using (-)-quinine as chiral auxiliary.
    Zhang Y; Chitale S; Goyal N; Li G; Han ZS; Shen S; Ma S; Grinberg N; Lee H; Lu BZ; Senanayake CH
    J Org Chem; 2012 Jan; 77(1):690-5. PubMed ID: 22126231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization.
    Okamoto N; Takeda K; Yanada R
    J Org Chem; 2010 Nov; 75(22):7615-25. PubMed ID: 20964314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.
    Chu W; Zhang J; Zeng C; Rothfuss J; Tu Z; Chu Y; Reichert DE; Welch MJ; Mach RH
    J Med Chem; 2005 Dec; 48(24):7637-47. PubMed ID: 16302804
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of biologically active amines via rhodium-bisphosphite-catalyzed hydroaminomethylation.
    Briggs JR; Klosin J; Whiteker GT
    Org Lett; 2005 Oct; 7(22):4795-8. PubMed ID: 16235891
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of substituted N-benzyl pyridones via an O- to N-alkyl migration.
    Lanni EL; Bosscher MA; Ooms BD; Shandro CA; Ellsworth BA; Anderson CE
    J Org Chem; 2008 Aug; 73(16):6425-8. PubMed ID: 18610979
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.