BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 24681946)

  • 1. SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylation.
    Seo KS; Park JH; Heo JY; Jing K; Han J; Min KN; Kim C; Koh GY; Lim K; Kang GY; Uee Lee J; Yim YH; Shong M; Kwak TH; Kweon GR
    Oncogene; 2015 Mar; 34(11):1354-62. PubMed ID: 24681946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RUNX3 inhibits hypoxia-inducible factor-1α protein stability by interacting with prolyl hydroxylases in gastric cancer cells.
    Lee SH; Bae SC; Kim KW; Lee YM
    Oncogene; 2014 Mar; 33(11):1458-67. PubMed ID: 23542169
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxia.
    Lee SD; Kim W; Jeong JW; Park JW; Kim JE
    Cancer Lett; 2016 Apr; 373(1):138-145. PubMed ID: 26808575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SIRT2 inhibition activates hypoxia-inducible factor 1α signaling and mediates neuronal survival.
    Kaitsuka T; Matsushita M; Matsushita N
    Biochem Biophys Res Commun; 2020 Sep; 529(4):957-962. PubMed ID: 32819605
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K; Seo S; Ki SH; Shin SM
    Free Radic Biol Med; 2016 Dec; 101():511-523. PubMed ID: 27840318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells.
    Lin HC; Su SL; Lu CY; Lin AH; Lin WC; Liu CS; Yang YC; Wang HM; Lii CK; Chen HW
    Environ Toxicol; 2017 Mar; 32(3):918-930. PubMed ID: 27297870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alternative regulation of HIF-1α stability through Phosphorylation on Ser451.
    Han HJ; Saeidi S; Kim SJ; Piao JY; Lim S; Guillen-Quispe YN; Choi BY; Surh YJ
    Biochem Biophys Res Commun; 2021 Mar; 545():150-156. PubMed ID: 33550096
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.
    Trisciuoglio D; Gabellini C; Desideri M; Ziparo E; Zupi G; Del Bufalo D
    PLoS One; 2010 Jul; 5(7):e11772. PubMed ID: 20668552
    [TBL] [Abstract][Full Text] [Related]  

  • 10. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
    Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
    Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours.
    Snell CE; Turley H; McIntyre A; Li D; Masiero M; Schofield CJ; Gatter KC; Harris AL; Pezzella F
    PLoS One; 2014; 9(2):e88955. PubMed ID: 24563687
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions.
    Laemmle A; Lechleiter A; Roh V; Schwarz C; Portmann S; Furer C; Keogh A; Tschan MP; Candinas D; Vorburger SA; Stroka D
    PLoS One; 2012; 7(3):e33433. PubMed ID: 22479397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha.
    Baek JH; Liu YV; McDonald KR; Wesley JB; Zhang H; Semenza GL
    J Biol Chem; 2007 Nov; 282(46):33358-33366. PubMed ID: 17875644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Decursin promotes HIF-1α proteasomal degradation and immune responses in hypoxic tumour microenvironment.
    Ge Y; Yoon SH; Jang H; Jeong JH; Lee YM
    Phytomedicine; 2020 Nov; 78():153318. PubMed ID: 32896707
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.
    Pagé EL; Chan DA; Giaccia AJ; Levine M; Richard DE
    Mol Biol Cell; 2008 Jan; 19(1):86-94. PubMed ID: 17942596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability.
    Park MH; Choi KY; Jung Y; Min do S
    Oncotarget; 2014 Dec; 5(23):11857-72. PubMed ID: 25361009
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.
    Foxler DE; Bridge KS; James V; Webb TM; Mee M; Wong SC; Feng Y; Constantin-Teodosiu D; Petursdottir TE; Bjornsson J; Ingvarsson S; Ratcliffe PJ; Longmore GD; Sharp TV
    Nat Cell Biol; 2012 Jan; 14(2):201-8. PubMed ID: 22286099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ERRα augments HIF-1 signalling by directly interacting with HIF-1α in normoxic and hypoxic prostate cancer cells.
    Zou C; Yu S; Xu Z; Wu D; Ng CF; Yao X; Yew DT; Vanacker JM; Chan FL
    J Pathol; 2014 May; 233(1):61-73. PubMed ID: 24425001
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Feedback regulation of ALDOA activates the HIF-1α/MMP9 axis to promote lung cancer progression.
    Chang YC; Chan YC; Chang WM; Lin YF; Yang CJ; Su CY; Huang MS; Wu ATH; Hsiao M
    Cancer Lett; 2017 Sep; 403():28-36. PubMed ID: 28610954
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endothelin-1 regulates hypoxia-inducible factor-1α and -2α stability through prolyl hydroxylase domain 2 inhibition in human lymphatic endothelial cells.
    Caprara V; Scappa S; Garrafa E; Di Castro V; Rosanò L; Bagnato A; Spinella F
    Life Sci; 2014 Nov; 118(2):185-90. PubMed ID: 24607784
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.