328 related articles for article (PubMed ID: 24681959)
1. Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.
Bharadwaj U; Eckols TK; Kolosov M; Kasembeli MM; Adam A; Torres D; Zhang X; Dobrolecki LE; Wei W; Lewis MT; Dave B; Chang JC; Landis MD; Creighton CJ; Mancini MA; Tweardy DJ
Oncogene; 2015 Mar; 34(11):1341-53. PubMed ID: 24681959
[TBL] [Abstract][Full Text] [Related]
2. Piperlongumine derivative, CG-06, inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells.
Kim YH; Yoon YJ; Lee YJ; Kim CH; Lee S; Choung DH; Han DC; Kwon BM
Bioorg Med Chem Lett; 2018 Aug; 28(14):2566-2572. PubMed ID: 29807795
[TBL] [Abstract][Full Text] [Related]
3. 10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation.
Zhao Q; Bi Y; Zhong J; Li X; Guo J; Liu YX; Pan LR; Tan Y; Deng ZS; Yu XJ
Acta Pharmacol Sin; 2021 May; 42(5):791-800. PubMed ID: 32868906
[TBL] [Abstract][Full Text] [Related]
4. A new synthetic derivative of cryptotanshinone KYZ3 as STAT3 inhibitor for triple-negative breast cancer therapy.
Zhang W; Yu W; Cai G; Zhu J; Zhang C; Li S; Guo J; Yin G; Chen C; Kong L
Cell Death Dis; 2018 Oct; 9(11):1098. PubMed ID: 30368518
[TBL] [Abstract][Full Text] [Related]
5. Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.
Lewis KM; Bharadwaj U; Eckols TK; Kolosov M; Kasembeli MM; Fridley C; Siller R; Tweardy DJ
Lung Cancer; 2015 Nov; 90(2):182-90. PubMed ID: 26410177
[TBL] [Abstract][Full Text] [Related]
6. Piperlongumine Induces Apoptosis and Synergizes with Doxorubicin by Inhibiting the JAK2-STAT3 Pathway in Triple-Negative Breast Cancer.
Chen D; Ma Y; Li P; Liu M; Fang Y; Zhang J; Zhang B; Hui Y; Yin Y
Molecules; 2019 Jun; 24(12):. PubMed ID: 31242627
[TBL] [Abstract][Full Text] [Related]
7. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
Duan Z; Bradner JE; Greenberg E; Levine R; Foster R; Mahoney J; Seiden MV
Clin Cancer Res; 2006 Nov; 12(22):6844-52. PubMed ID: 17121906
[TBL] [Abstract][Full Text] [Related]
8. Piperlongumine inhibits the proliferation and survival of B-cell acute lymphoblastic leukemia cell lines irrespective of glucocorticoid resistance.
Han SS; Han S; Kamberos NL
Biochem Biophys Res Commun; 2014 Sep; 452(3):669-75. PubMed ID: 25193702
[TBL] [Abstract][Full Text] [Related]
9. Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway.
Wang J; Zhang L; Chen G; Zhang J; Li Z; Lu W; Liu M; Pang X
Breast Cancer Res Treat; 2014 Nov; 148(2):279-89. PubMed ID: 25301089
[TBL] [Abstract][Full Text] [Related]
10. Scoparone exerts anti-tumor activity against DU145 prostate cancer cells via inhibition of STAT3 activity.
Kim JK; Kim JY; Kim HJ; Park KG; Harris RA; Cho WJ; Lee JT; Lee IK
PLoS One; 2013; 8(11):e80391. PubMed ID: 24260381
[TBL] [Abstract][Full Text] [Related]
11. Two Natural Alkaloids Synergistically Induce Apoptosis in Breast Cancer Cells by Inhibiting STAT3 Activation.
Chen D; Ma Y; Guo Z; Liu L; Yang Y; Wang Y; Pan B; Wu L; Hui Y; Yang W
Molecules; 2020 Jan; 25(1):. PubMed ID: 31948057
[TBL] [Abstract][Full Text] [Related]
12. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
Duan Z; Bradner J; Greenberg E; Mazitschek R; Foster R; Mahoney J; Seiden MV
Mol Pharmacol; 2007 Nov; 72(5):1137-45. PubMed ID: 17675586
[TBL] [Abstract][Full Text] [Related]
13. Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells.
Yao Y; Sun Y; Shi M; Xia D; Zhao K; Zeng L; Yao R; Zhang Y; Li Z; Niu M; Xu K
Oncotarget; 2016 Nov; 7(45):73497-73508. PubMed ID: 27634873
[TBL] [Abstract][Full Text] [Related]
14. Piperlongumine inhibits head and neck squamous cell carcinoma proliferation by docking to Akt.
Lv F; Deng M; Bai J; Zou D; Wang J; Li H; Zhang Y; Ji X
Phytother Res; 2020 Dec; 34(12):3345-3358. PubMed ID: 32798277
[TBL] [Abstract][Full Text] [Related]
15. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
Lin L; Hutzen B; Li PK; Ball S; Zuo M; DeAngelis S; Foust E; Sobo M; Friedman L; Bhasin D; Cen L; Li C; Lin J
Neoplasia; 2010 Jan; 12(1):39-50. PubMed ID: 20072652
[TBL] [Abstract][Full Text] [Related]
16. STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits.
Chung SS; Giehl N; Wu Y; Vadgama JV
Int J Oncol; 2014 Feb; 44(2):403-11. PubMed ID: 24297508
[TBL] [Abstract][Full Text] [Related]
17. Chemical probes that competitively and selectively inhibit Stat3 activation.
Xu X; Kasembeli MM; Jiang X; Tweardy BJ; Tweardy DJ
PLoS One; 2009; 4(3):e4783. PubMed ID: 19274102
[TBL] [Abstract][Full Text] [Related]
18. Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo.
Mohan CD; Bharathkumar H; Bulusu KC; Pandey V; Rangappa S; Fuchs JE; Shanmugam MK; Dai X; Li F; Deivasigamani A; Hui KM; Kumar AP; Lobie PE; Bender A; Basappa ; Sethi G; Rangappa KS
J Biol Chem; 2014 Dec; 289(49):34296-307. PubMed ID: 25320076
[TBL] [Abstract][Full Text] [Related]
19. Ginkgetin inhibits the growth of DU-145 prostate cancer cells through inhibition of signal transducer and activator of transcription 3 activity.
Jeon YJ; Jung SN; Yun J; Lee CW; Choi J; Lee YJ; Han DC; Kwon BM
Cancer Sci; 2015 Apr; 106(4):413-20. PubMed ID: 25611086
[TBL] [Abstract][Full Text] [Related]
20. Piperlongumine inhibits gastric cancer cells via suppression of the JAK1,2/STAT3 signaling pathway.
Song B; Zhan H; Bian Q; Gu J
Mol Med Rep; 2016 May; 13(5):4475-80. PubMed ID: 27053336
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
