176 related articles for article (PubMed ID: 24682532)
1. The impact of 5-formyltetrahydrofolate on the anti-tumor activity of pralatrexate, as compared to methotrexate, in HeLa cells in vitro.
Visentin M; Unal ES; Goldman ID
Cancer Chemother Pharmacol; 2014 May; 73(5):1055-62. PubMed ID: 24682532
[TBL] [Abstract][Full Text] [Related]
2. The membrane transport and polyglutamation of pralatrexate: a new-generation dihydrofolate reductase inhibitor.
Visentin M; Unal ES; Zhao R; Goldman ID
Cancer Chemother Pharmacol; 2013 Sep; 72(3):597-606. PubMed ID: 23881211
[TBL] [Abstract][Full Text] [Related]
3. Distinct mechanistic activity profile of pralatrexate in comparison to other antifolates in in vitro and in vivo models of human cancers.
Izbicka E; Diaz A; Streeper R; Wick M; Campos D; Steffen R; Saunders M
Cancer Chemother Pharmacol; 2009 Oct; 64(5):993-9. PubMed ID: 19221750
[TBL] [Abstract][Full Text] [Related]
4. Single agent and combination studies of pralatrexate and molecular correlates of sensitivity.
Serova M; Bieche I; Sablin MP; Pronk GJ; Vidaud M; Cvitkovic E; Faivre S; Raymond E
Br J Cancer; 2011 Jan; 104(2):272-80. PubMed ID: 21179031
[TBL] [Abstract][Full Text] [Related]
5. Leucovorin rescue allows effective high-dose pralatrexate treatment and an increase in therapeutic index in mesothelioma xenografts.
Tedeschi PM; Kathari YK; Farooqi IN; Bertino JR
Cancer Chemother Pharmacol; 2014 Nov; 74(5):1029-32. PubMed ID: 25205429
[TBL] [Abstract][Full Text] [Related]
6. In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
van der Laan BF; Jansen G; Kathmann GA; Westerhof GR; Schornagel JH; Hordijk GJ
Int J Cancer; 1992 Jul; 51(6):909-14. PubMed ID: 1639538
[TBL] [Abstract][Full Text] [Related]
7. Novel 6,5-fused ring heterocyclic antifolates: biochemical and biological characterization.
McGuire JJ; Bergoltz VV; Heitzman KJ; Haile WH; Russell CA; Bolanowska WE; Kotake Y; Haneda T; Nomura H
Cancer Res; 1994 May; 54(10):2673-9. PubMed ID: 8168096
[TBL] [Abstract][Full Text] [Related]
8. Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.
Braakhuis BJ; Jansen G; Noordhuis P; Kegel A; Peters GJ
Biochem Pharmacol; 1993 Dec; 46(12):2155-61. PubMed ID: 7506025
[TBL] [Abstract][Full Text] [Related]
9. Effect of nitrous oxide and methotrexate on folate coenzyme pools of blast cells from leukemia patients.
Ermens AA; Schoester M; Lindemans J; Abels J
Leuk Res; 1991; 15(2-3):165-71. PubMed ID: 2016907
[TBL] [Abstract][Full Text] [Related]
10. Pralatrexate - from bench to bedside.
Zain JM; Marchi E
Drugs Today (Barc); 2010 Feb; 46(2):91-9. PubMed ID: 20393637
[TBL] [Abstract][Full Text] [Related]
11. Pralatrexate Monitoring Using a Commercially Available Methotrexate Assay to Avoid Potential Drug Interactions.
McPherson JP; Vrontikis A; Sedillo C; Halwani AS; Gilreath JA
Pharmacotherapy; 2016 Feb; 36(2):e8-e11. PubMed ID: 26809959
[TBL] [Abstract][Full Text] [Related]
12. Pralatrexate, a dihydrofolate reductase inhibitor for the potential treatment of several malignancies.
Molina JR
IDrugs; 2008 Jul; 11(7):508-21. PubMed ID: 18600598
[TBL] [Abstract][Full Text] [Related]
13. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
[TBL] [Abstract][Full Text] [Related]
14. Biochemical and growth inhibition studies of methotrexate and aminopterin analogues containing a tetrazole ring in place of the gamma-carboxyl group.
McGuire JJ; Russell CA; Bolanowska WE; Freitag CM; Jones CS; Kalman TI
Cancer Res; 1990 Mar; 50(6):1726-31. PubMed ID: 2306727
[TBL] [Abstract][Full Text] [Related]
15. Cytotoxicity, uptake, polyglutamate formation, and antileukemic effects of 8-deaza analogues of methotrexate and aminopterin in mice.
Kuehl M; Brixner DI; Broom AD; Avery TL; Blakley RL
Cancer Res; 1988 Mar; 48(6):1481-8. PubMed ID: 2449950
[TBL] [Abstract][Full Text] [Related]
16. A phase 1 study of pralatrexate in combination with paclitaxel or docetaxel in patients with advanced solid tumors.
Azzoli CG; Krug LM; Gomez J; Miller VA; Kris MG; Ginsberg MS; Henry R; Jones J; Tyson L; Dunne M; Pizzo B; Farmer A; Venkatraman E; Steffen R; Sirotnak FM
Clin Cancer Res; 2007 May; 13(9):2692-8. PubMed ID: 17473201
[TBL] [Abstract][Full Text] [Related]
17. A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice.
Sirotnak FM; DeGraw JI; Colwell WT; Piper JR
Cancer Chemother Pharmacol; 1998; 42(4):313-8. PubMed ID: 9744777
[TBL] [Abstract][Full Text] [Related]
18. The schedule-dependent effects of the novel antifolate pralatrexate and gemcitabine are superior to methotrexate and cytarabine in models of human non-Hodgkin's lymphoma.
Toner LE; Vrhovac R; Smith EA; Gardner J; Heaney M; Gonen M; Teruya-Feldstein J; Sirotnak F; O'Connor OA
Clin Cancer Res; 2006 Feb; 12(3 Pt 1):924-32. PubMed ID: 16467107
[TBL] [Abstract][Full Text] [Related]
19. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
Jansen G; Mauritz RM; Assaraf YG; Sprecher H; Drori S; Kathmann I; Westerhof GR; Priest DG; Bunni M; Pinedo HM; Schornagel JH; Peters GJ
Adv Enzyme Regul; 1997; 37():59-76. PubMed ID: 9381986
[TBL] [Abstract][Full Text] [Related]
20. Methotrexate and Pralatrexate.
Wood GS; Wu J
Dermatol Clin; 2015 Oct; 33(4):747-55. PubMed ID: 26433846
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
