BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 24685158)

  • 1. Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR.
    Houck SA; Ren HY; Madden VJ; Bonner JN; Conlin MP; Janovick JA; Conn PM; Cyr DM
    Mol Cell; 2014 Apr; 54(1):166-179. PubMed ID: 24685158
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy.
    He L; Kennedy AS; Houck S; Aleksandrov A; Quinney NL; Cyr-Scully A; Cholon DM; Gentzsch M; Randell SH; Ren HY; Cyr DM
    Mol Biol Cell; 2021 Apr; 32(7):538-553. PubMed ID: 33534640
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis.
    Sopha P; Ren HY; Grove DE; Cyr DM
    J Biol Chem; 2017 Jul; 292(28):11792-11803. PubMed ID: 28536268
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel mammalian ER-located J-protein, DNAJB14, can accelerate ERAD of misfolded membrane proteins.
    Sopha P; Kadokura H; Yamamoto YH; Takeuchi M; Saito M; Tsuru A; Kohno K
    Cell Struct Funct; 2012; 37(2):177-87. PubMed ID: 23018488
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect.
    Brothers SP; Cornea A; Janovick JA; Conn PM
    Mol Endocrinol; 2004 Jul; 18(7):1787-97. PubMed ID: 15105440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNAJB12 and Hsp70 Mediate Triage of Misfolded Membrane Proteins for Proteasomal versus Lysosomal Degradation.
    Kennedy A; Cyr DM
    Autophagy Rep; 2022; 1(1):559-562. PubMed ID: 36743458
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress.
    Kondratyev M; Avezov E; Shenkman M; Groisman B; Lederkremer GZ
    Exp Cell Res; 2007 Oct; 313(16):3395-407. PubMed ID: 17707796
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The endoplasmic reticulum-associated degradation and disulfide reductase ERdj5.
    Ushioda R; Nagata K
    Methods Enzymol; 2011; 490():235-58. PubMed ID: 21266254
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.
    Huyer G; Piluek WF; Fansler Z; Kreft SG; Hochstrasser M; Brodsky JL; Michaelis S
    J Biol Chem; 2004 Sep; 279(37):38369-78. PubMed ID: 15252059
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Use of pharmacoperones to reveal GPCR structural changes associated with constitutive activation and trafficking.
    Janovick JA; Conn PM
    Methods Enzymol; 2010; 485():277-92. PubMed ID: 21050923
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disposing of misfolded ER proteins: A troubled substrate's way out of the ER.
    Oikonomou C; Hendershot LM
    Mol Cell Endocrinol; 2020 Jan; 500():110630. PubMed ID: 31669350
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Herp coordinates compartmentalization and recruitment of HRD1 and misfolded proteins for ERAD.
    Leitman J; Shenkman M; Gofman Y; Shtern NO; Ben-Tal N; Hendershot LM; Lederkremer GZ
    Mol Biol Cell; 2014 Apr; 25(7):1050-60. PubMed ID: 24478453
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteasomal and lysosomal clearance of faulty secretory proteins: ER-associated degradation (ERAD) and ER-to-lysosome-associated degradation (ERLAD) pathways.
    Fregno I; Molinari M
    Crit Rev Biochem Mol Biol; 2019 Apr; 54(2):153-163. PubMed ID: 31084437
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.
    Chiritoiu M; Chiritoiu GN; Munteanu CVA; Pastrama F; Ivessa NE; Petrescu SM
    Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32423001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fusion of an intact secretory protein permits a misfolded protein to exit from the endoplasmic reticulum in yeast.
    Suyama K; Hori M; Gomi K; Shintani T
    Biosci Biotechnol Biochem; 2014; 78(1):49-59. PubMed ID: 25036483
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rescue of misrouted GnRHR mutants reveals its constitutive activity.
    Janovick JA; Pogozheva ID; Mosberg HI; Cornea A; Conn PM
    Mol Endocrinol; 2012 Jul; 26(7):1179-88. PubMed ID: 22595961
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity.
    Lamriben L; Oster ME; Tamura T; Tian W; Yang Z; Clausen H; Hebert DN
    J Biol Chem; 2018 Sep; 293(36):13932-13945. PubMed ID: 30021839
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.
    Ushioda R; Hoseki J; Araki K; Jansen G; Thomas DY; Nagata K
    Science; 2008 Jul; 321(5888):569-72. PubMed ID: 18653895
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.
    Ishida Y; Yamamoto A; Kitamura A; Lamandé SR; Yoshimori T; Bateman JF; Kubota H; Nagata K
    Mol Biol Cell; 2009 Jun; 20(11):2744-54. PubMed ID: 19357194
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Turnover of EDEM1, an ERAD-enhancing factor, is mediated by multiple degradation routes.
    Katsuki R; Kanuka M; Ohta R; Yoshida S; Tamura T
    Genes Cells; 2024 Apr; ():. PubMed ID: 38682256
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.