BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 24687871)

  • 1. Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance.
    Monsma DJ; Cherba DM; Richardson PJ; Vance S; Rangarajan S; Dylewski D; Eugster E; Scott SB; Beuschel NL; Davidson PJ; Axtell R; Mitchell D; Lester EP; Junewick JJ; Webb CP; Monks NR
    Pediatr Blood Cancer; 2014 Sep; 61(9):1570-7. PubMed ID: 24687871
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurrent tumors.
    Manzella G; Moonamale DC; Römmele M; Bode P; Wachtel M; Schäfer BW
    Neoplasia; 2021 Sep; 23(9):929-938. PubMed ID: 34329950
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preclinical rationale for entinostat in embryonal rhabdomyosarcoma.
    Bharathy N; Berlow NE; Wang E; Abraham J; Settelmeyer TP; Hooper JE; Svalina MN; Bajwa Z; Goros MW; Hernandez BS; Wolff JE; Pal R; Davies AM; Ashok A; Bushby D; Mancini M; Noakes C; Goodwin NC; Ordentlich P; Keck J; Hawkins DS; Rudzinski ER; Mansoor A; Perkins TJ; Vakoc CR; Michalek JE; Keller C
    Skelet Muscle; 2019 May; 9(1):12. PubMed ID: 31113472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer.
    Dobbin ZC; Katre AA; Steg AD; Erickson BK; Shah MM; Alvarez RD; Conner MG; Schneider D; Chen D; Landen CN
    Oncotarget; 2014 Sep; 5(18):8750-64. PubMed ID: 25209969
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma.
    Berlow NE; Rikhi R; Geltzeiler M; Abraham J; Svalina MN; Davis LE; Wise E; Mancini M; Noujaim J; Mansoor A; Quist MJ; Matlock KL; Goros MW; Hernandez BS; Doung YC; Thway K; Tsukahara T; Nishio J; Huang ET; Airhart S; Bult CJ; Gandour-Edwards R; Maki RG; Jones RL; Michalek JE; Milovancev M; Ghosh S; Pal R; Keller C
    BMC Cancer; 2019 Jun; 19(1):593. PubMed ID: 31208434
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies.
    Krepler C; Xiao M; Sproesser K; Brafford PA; Shannan B; Beqiri M; Liu Q; Xu W; Garman B; Nathanson KL; Xu X; Karakousis GC; Mills GB; Lu Y; Ahmed TA; Poulikakos PI; Caponigro G; Boehm M; Peters M; Schuchter LM; Weeraratna AT; Herlyn M
    Clin Cancer Res; 2016 Apr; 22(7):1592-602. PubMed ID: 26673799
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of glutathione-S-transferase as a treatment strategy for multidrug resistance in childhood rhabdomyosarcoma.
    Seitz G; Bonin M; Fuchs J; Poths S; Ruck P; Warmann SW; Armeanu-Ebinger S
    Int J Oncol; 2010 Feb; 36(2):491-500. PubMed ID: 20043085
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Using the neoadjuvant chemotherapy paradigm to develop precision therapy for muscle-invasive bladder cancer.
    Chedgy EC; Douglas J; Wright JL; Seiler R; van Rhijn BW; Boormans J; Todenhöfer T; Dinney CP; Collins CC; Van der Heijden MS; Black PC
    Urol Oncol; 2016 Oct; 34(10):469-76. PubMed ID: 27317490
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PDXGEM: patient-derived tumor xenograft-based gene expression model for predicting clinical response to anticancer therapy in cancer patients.
    Kim Y; Kim D; Cao B; Carvajal R; Kim M
    BMC Bioinformatics; 2020 Jul; 21(1):288. PubMed ID: 32631229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts.
    Palmer AC; Plana D; Gao H; Korn JM; Yang G; Green J; Zhang X; Velazquez R; McLaughlin ME; Ruddy DA; Kowal C; Muszynski J; Bullock C; Rivera S; Rakiec DP; Elliott G; Fordjour P; Meyer R; Loo A; Kurth E; Engelman JA; Bitter H; Sellers WR; Williams JA; Sorger PK
    Cancer Res; 2020 Oct; 80(19):4278-4287. PubMed ID: 32747364
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells.
    Wachtel M; Rakic J; Okoniewski M; Bode P; Niggli F; Schäfer BW
    Int J Cancer; 2014 Oct; 135(7):1543-52. PubMed ID: 24550147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of MT4-MMP, EGFR, and RB in Triple-Negative Breast Cancer Strongly Sensitizes Tumors to Erlotinib and Palbociclib Combination Therapy.
    Foidart P; Yip C; Radermacher J; Blacher S; Lienard M; Montero-Ruiz L; Maquoi E; Montaudon E; Château-Joubert S; Collignon J; Coibion M; Jossa V; Marangoni E; Noël A; Sounni NE; Jerusalem G
    Clin Cancer Res; 2019 Mar; 25(6):1838-1850. PubMed ID: 30504427
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance.
    Grasse S; Lienhard M; Frese S; Kerick M; Steinbach A; Grimm C; Hussong M; Rolff J; Becker M; Dreher F; Schirmer U; Boerno S; Ramisch A; Leschber G; Timmermann B; Grohé C; Lüders H; Vingron M; Fichtner I; Klein S; Odenthal M; Büttner R; Lehrach H; Sültmann H; Herwig R; Schweiger MR
    Genome Med; 2018 Jul; 10(1):55. PubMed ID: 30029672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fusion status in patients with lymph node-positive (N1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: Experience of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG).
    Gallego S; Zanetti I; Orbach D; Ranchère D; Shipley J; Zin A; Bergeron C; de Salvo GL; Chisholm J; Ferrari A; Jenney M; Mandeville HC; Rogers T; Merks JHM; Mudry P; Glosli H; Milano GM; Ferman S; Bisogno G;
    Cancer; 2018 Aug; 124(15):3201-3209. PubMed ID: 29797665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer.
    Owonikoko TK; Zhang G; Kim HS; Stinson RM; Bechara R; Zhang C; Chen Z; Saba NF; Pakkala S; Pillai R; Deng X; Sun SY; Rossi MR; Sica GL; Ramalingam SS; Khuri FR
    J Transl Med; 2016 May; 14(1):111. PubMed ID: 27142472
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Precision medicine approaches to lung adenocarcinoma with concomitant MET and HER2 amplification.
    Oh DY; Jung K; Song JY; Kim S; Shin S; Kwon YJ; Oh E; Park WY; Song SY; Choi YL
    BMC Cancer; 2017 Aug; 17(1):535. PubMed ID: 28806950
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.
    Hersh DS; Harder BG; Roos A; Peng S; Heath JE; Legesse T; Kim AJ; Woodworth GF; Tran NL; Winkles JA
    Neuro Oncol; 2018 Sep; 20(10):1321-1330. PubMed ID: 29897522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alveolar rhabdomyosarcoma: morphoproteomics and personalized tumor graft testing further define the biology of PAX3-FKHR(FOXO1) subtype and provide targeted therapeutic options.
    Brown RE; Buryanek J; Katz AM; Paz K; Wolff JE
    Oncotarget; 2016 Jul; 7(29):46263-46272. PubMed ID: 27323832
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Chemoresistance in Primary Tumor Cells by
    Giorgi C; Gasser UE; Lafont ME; Holzgang HE; Thalhammer VF
    Anticancer Res; 2019 Aug; 39(8):4101-4110. PubMed ID: 31366494
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.
    Capasso A; Lang J; Pitts TM; Jordan KR; Lieu CH; Davis SL; Diamond JR; Kopetz S; Barbee J; Peterson J; Freed BM; Yacob BW; Bagby SM; Messersmith WA; Slansky JE; Pelanda R; Eckhardt SG
    J Immunother Cancer; 2019 Feb; 7(1):37. PubMed ID: 30736857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.