BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 24691127)

  • 1. Extracellular Hb enhances cardiac toxicity in endotoxemic guinea pigs: protective role of haptoglobin.
    Baek JH; Zhang X; Williams MC; Schaer DJ; Buehler PW; D'Agnillo F
    Toxins (Basel); 2014 Mar; 6(4):1244-59. PubMed ID: 24691127
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs.
    Boretti FS; Buehler PW; D'Agnillo F; Kluge K; Glaus T; Butt OI; Jia Y; Goede J; Pereira CP; Maggiorini M; Schoedon G; Alayash AI; Schaer DJ
    J Clin Invest; 2009 Aug; 119(8):2271-80. PubMed ID: 19620788
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hemopexin increases the neurotoxicity of hemoglobin when haptoglobin is absent.
    Chen-Roetling J; Ma SK; Cao Y; Shah A; Regan RF
    J Neurochem; 2018 Jun; 145(6):464-473. PubMed ID: 29500821
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Infusion of esmolol attenuates lipopolysaccharide-induced myocardial dysfunction.
    Wang Z; Wu Q; Nie X; Guo J; Yang C
    J Surg Res; 2016 Jan; 200(1):283-9. PubMed ID: 26316443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Haptoglobin attenuates hemoglobin-induced heme oxygenase-1 in renal proximal tubule cells and kidneys of a mouse model of sickle cell disease.
    Chintagari NR; Nguyen J; Belcher JD; Vercellotti GM; Alayash AI
    Blood Cells Mol Dis; 2015 Mar; 54(3):302-6. PubMed ID: 25582460
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Haptoglobin Therapeutics and Compartmentalization of Cell-Free Hemoglobin Toxicity.
    Buehler PW; Humar R; Schaer DJ
    Trends Mol Med; 2020 Jul; 26(7):683-697. PubMed ID: 32589936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human Hp1-1 and Hp2-2 phenotype-specific haptoglobin therapeutics are both effective in vitro and in guinea pigs to attenuate hemoglobin toxicity.
    Lipiski M; Deuel JW; Baek JH; Engelsberger WR; Buehler PW; Schaer DJ
    Antioxid Redox Signal; 2013 Nov; 19(14):1619-33. PubMed ID: 23418677
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration.
    Irwin DC; Baek JH; Hassell K; Nuss R; Eigenberger P; Lisk C; Loomis Z; Maltzahn J; Stenmark KR; Nozik-Grayck E; Buehler PW
    Free Radic Biol Med; 2015 May; 82():50-62. PubMed ID: 25656991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy.
    Baek JH; D'Agnillo F; Vallelian F; Pereira CP; Williams MC; Jia Y; Schaer DJ; Buehler PW
    J Clin Invest; 2012 Apr; 122(4):1444-58. PubMed ID: 22446185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease.
    Yalamanoglu A; Deuel JW; Hunt RC; Baek JH; Hassell K; Redinius K; Irwin DC; Schaer DJ; Buehler PW
    Am J Physiol Lung Cell Mol Physiol; 2018 Nov; 315(5):L765-L774. PubMed ID: 30047285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deletion of capn4 Protects the Heart Against Endotoxemic Injury by Preventing ATP Synthase Disruption and Inhibiting Mitochondrial Superoxide Generation.
    Ni R; Zheng D; Wang Q; Yu Y; Chen R; Sun T; Wang W; Fan GC; Greer PA; Gardiner RB; Peng T
    Circ Heart Fail; 2015 Sep; 8(5):988-96. PubMed ID: 26246018
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sodium nitrite potentiates renal oxidative stress and injury in hemoglobin exposed guinea pigs.
    Baek JH; Zhang X; Williams MC; Hicks W; Buehler PW; D'Agnillo F
    Toxicology; 2015 Jul; 333():89-99. PubMed ID: 25891524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cardiac-specific expression of heat shock protein 27 attenuated endotoxin-induced cardiac dysfunction and mortality in mice through a PI3K/Akt-dependent mechanism.
    You W; Min X; Zhang X; Qian B; Pang S; Ding Z; Li C; Gao X; Di R; Cheng Y; Liu L
    Shock; 2009 Jul; 32(1):108-17. PubMed ID: 19106822
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity.
    Deuel JW; Vallelian F; Schaer CA; Puglia M; Buehler PW; Schaer DJ
    Free Radic Biol Med; 2015 Dec; 89():931-43. PubMed ID: 26475040
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme.
    Munoz CJ; Pires IS; Baek JH; Buehler PW; Palmer AF; Cabrales P
    Am J Physiol Heart Circ Physiol; 2020 May; 318(5):H1296-H1307. PubMed ID: 32302494
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of hemoglobin-induced protection against endotoxemia in rats: a ferritin-independent pathway.
    Otterbein L; Chin BY; Otterbein SL; Lowe VC; Fessler HE; Choi AM
    Am J Physiol; 1997 Feb; 272(2 Pt 1):L268-75. PubMed ID: 9124378
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Renal Toxicodynamic Effects of Extracellular Hemoglobin After Acute Exposure.
    Baek JH; Yalamanoglu A; Brown RP; Saylor DM; Malinauskas RA; Buehler PW
    Toxicol Sci; 2018 Nov; 166(1):180-191. PubMed ID: 30085279
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction.
    Tian W; Guo HS; Li CY; Cao W; Wang XY; Mo D; Hao XW; Feng YD; Sun Y; Lei F; Zhang HN; Zhao MG; Li XQ
    Toxicol Appl Pharmacol; 2019 Apr; 368():26-36. PubMed ID: 30776389
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitogen-activated protein kinase phosphatase-1 inhibits myocardial TNF-α expression and improves cardiac function during endotoxemia.
    Zhang T; Lu X; Arnold P; Liu Y; Baliga R; Huang H; Bauer JA; Liu Y; Feng Q
    Cardiovasc Res; 2012 Mar; 93(3):471-9. PubMed ID: 22198506
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by
    Mikkelsen JH; Runager K; Andersen CBF
    J Biol Chem; 2020 Feb; 295(7):1781-1791. PubMed ID: 31819010
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.