BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 24692446)

  • 1. Phosphoinositide-mediated oligomerization of a defensin induces cell lysis.
    Poon IKh; Baxter AA; Lay FT; Mills GD; Adda CG; Payne JA; Phan TK; Ryan GF; White JA; Veneer PK; van der Weerden NL; Anderson MA; Kvansakul M; Hulett MD
    Elife; 2014 Apr; 3():e01808. PubMed ID: 24692446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis.
    Baxter AA; Richter V; Lay FT; Poon IK; Adda CG; Veneer PK; Phan TK; Bleackley MR; Anderson MA; Kvansakul M; Hulett MD
    Mol Cell Biol; 2015 Jun; 35(11):1964-78. PubMed ID: 25802281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the defensin NsD7 in complex with PIP
    Järvå M; Lay FT; Hulett MD; Kvansakul M
    FEBS Lett; 2017 Aug; 591(16):2482-2490. PubMed ID: 28741756
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dimerization of plant defensin NaD1 enhances its antifungal activity.
    Lay FT; Mills GD; Poon IK; Cowieson NP; Kirby N; Baxter AA; van der Weerden NL; Dogovski C; Perugini MA; Anderson MA; Kvansakul M; Hulett MD
    J Biol Chem; 2012 Jun; 287(24):19961-72. PubMed ID: 22511788
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural and functional characterization of the membrane-permeabilizing activity of
    Lay FT; Ryan GF; Caria S; Phan TK; Veneer PK; White JA; Kvansakul M; Hulett MD
    FASEB J; 2019 May; 33(5):6470-6482. PubMed ID: 30794440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.
    Järvå M; Lay FT; Phan TK; Humble C; Poon IKH; Bleackley MR; Anderson MA; Hulett MD; Kvansakul M
    Nat Commun; 2018 May; 9(1):1962. PubMed ID: 29773800
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Permeabilization of fungal hyphae by the plant defensin NaD1 occurs through a cell wall-dependent process.
    van der Weerden NL; Hancock RE; Anderson MA
    J Biol Chem; 2010 Nov; 285(48):37513-20. PubMed ID: 20861017
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human β-defensin 2 kills
    Järvå M; Phan TK; Lay FT; Caria S; Kvansakul M; Hulett MD
    Sci Adv; 2018 Jul; 4(7):eaat0979. PubMed ID: 30050988
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
    Kvansakul M; Lay FT; Adda CG; Veneer PK; Baxter AA; Phan TK; Poon IK; Hulett MD
    Proc Natl Acad Sci U S A; 2016 Oct; 113(40):11202-11207. PubMed ID: 27647905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process.
    Baxter AA; Poon IK; Hulett MD
    Cell Death Discov; 2017; 3():16102. PubMed ID: 28179997
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant.
    Bleackley MR; Payne JA; Hayes BM; Durek T; Craik DJ; Shafee TM; Poon IK; Hulett MD; van der Weerden NL; Anderson MA
    Antimicrob Agents Chemother; 2016 Oct; 60(10):6302-12. PubMed ID: 27503651
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation.
    Phan TK; Lay FT; Poon IK; Hinds MG; Kvansakul M; Hulett MD
    Oncotarget; 2016 Jan; 7(2):2054-69. PubMed ID: 26657293
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate.
    Payne JA; Bleackley MR; Lee TH; Shafee TM; Poon IK; Hulett MD; Aguilar MI; van der Weerden NL; Anderson MA
    Biochim Biophys Acta; 2016 Jun; 1858(6):1099-109. PubMed ID: 26896695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and mechanism of action of the plant defensin NaD1 as a new member of the antifungal drug arsenal against Candida albicans.
    Hayes BM; Bleackley MR; Wiltshire JL; Anderson MA; Traven A; van der Weerden NL
    Antimicrob Agents Chemother; 2013 Aug; 57(8):3667-75. PubMed ID: 23689717
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae.
    van der Weerden NL; Lay FT; Anderson MA
    J Biol Chem; 2008 May; 283(21):14445-52. PubMed ID: 18339623
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of cereal rust fungi by both class I and II defensins derived from the flowers of Nicotiana alata.
    Dracatos PM; van der Weerden NL; Carroll KT; Johnson ED; Plummer KM; Anderson MA
    Mol Plant Pathol; 2014 Jan; 15(1):67-79. PubMed ID: 24015961
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel bi-domain plant defensin MtDef5 with potent broad-spectrum antifungal activity binds to multiple phospholipids and forms oligomers.
    Islam KT; Velivelli SLS; Berg RH; Oakley B; Shah DM
    Sci Rep; 2017 Nov; 7(1):16157. PubMed ID: 29170445
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of rice defensin OsAFP1 and molecular insight into lipid-binding.
    Ochiai A; Ogawa K; Fukuda M; Suzuki M; Ito K; Tanaka T; Sagehashi Y; Taniguchi M
    J Biosci Bioeng; 2020 Jul; 130(1):6-13. PubMed ID: 32192842
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1.
    Lay FT; Mills GD; Hulett MD; Kvansakul M
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Jan; 68(Pt 1):85-8. PubMed ID: 22232180
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The structure of human beta-defensin-2 shows evidence of higher order oligomerization.
    Hoover DM; Rajashankar KR; Blumenthal R; Puri A; Oppenheim JJ; Chertov O; Lubkowski J
    J Biol Chem; 2000 Oct; 275(42):32911-8. PubMed ID: 10906336
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.