BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 24694247)

  • 1. Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase β.
    Koag MC; Lee S
    J Am Chem Soc; 2014 Apr; 136(15):5709-21. PubMed ID: 24694247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine.
    Koag MC; Kou Y; Ouzon-Shubeita H; Lee S
    Nucleic Acids Res; 2014 Jul; 42(13):8755-66. PubMed ID: 24966350
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β.
    Koag MC; Lee S
    Biochem J; 2018 Feb; 475(3):571-585. PubMed ID: 29301983
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Replication.
    Kou Y; Koag MC; Lee S
    Biochemistry; 2018 Aug; 57(34):5105-5116. PubMed ID: 29957995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for promutagenicity of 8-halogenated guanine.
    Koag MC; Min K; Lee S
    J Biol Chem; 2014 Feb; 289(9):6289-98. PubMed ID: 24425881
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase β.
    Koag MC; Lai L; Lee S
    J Biol Chem; 2014 Nov; 289(45):31341-8. PubMed ID: 25237188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase β.
    Koag MC; Nam K; Lee S
    Nucleic Acids Res; 2014; 42(17):11233-45. PubMed ID: 25200079
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota.
    Pence MG; Choi JY; Egli M; Guengerich FP
    J Biol Chem; 2010 Dec; 285(52):40666-72. PubMed ID: 20961860
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
    Kou Y; Koag MC; Lee S
    Molecules; 2019 Sep; 24(19):. PubMed ID: 31569643
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4.
    Jung H; Lee S
    Biochem J; 2020 Aug; 477(15):2859-2871. PubMed ID: 32686822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity.
    Arora K; Beard WA; Wilson SH; Schlick T
    Biochemistry; 2005 Oct; 44(40):13328-41. PubMed ID: 16201758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mismatched base-pair simulations for ASFV Pol X/DNA complexes help interpret frequent G*G misincorporation.
    Sampoli Benítez BA; Arora K; Balistreri L; Schlick T
    J Mol Biol; 2008 Dec; 384(5):1086-97. PubMed ID: 18955064
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred.
    Eoff RL; Irimia A; Egli M; Guengerich FP
    J Biol Chem; 2007 Jan; 282(2):1456-67. PubMed ID: 17105728
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing.
    Eoff RL; Angel KC; Egli M; Guengerich FP
    J Biol Chem; 2007 May; 282(18):13573-84. PubMed ID: 17337730
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
    Koag MC; Jung H; Lee S
    J Am Chem Soc; 2019 Mar; 141(11):4584-4596. PubMed ID: 30817143
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site.
    Batra VK; Beard WA; Hou EW; Pedersen LC; Prasad R; Wilson SH
    Nat Struct Mol Biol; 2010 Jul; 17(7):889-90. PubMed ID: 20526335
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of N7-Alkylguanine Conformation and Metal Cofactors on the Translesion Synthesis by Human DNA Polymerase η.
    Jung H; Rayala NK; Lee S
    Chem Res Toxicol; 2022 Mar; 35(3):512-521. PubMed ID: 35239327
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography.
    Vyas R; Reed AJ; Tokarsky EJ; Suo Z
    J Am Chem Soc; 2015 Apr; 137(15):5225-30. PubMed ID: 25825995
    [TBL] [Abstract][Full Text] [Related]  

  • 19. How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.
    Wu WJ; Su MI; Wu JL; Kumar S; Lim LH; Wang CW; Nelissen FH; Chen MC; Doreleijers JF; Wijmenga SS; Tsai MD
    J Am Chem Soc; 2014 Apr; 136(13):4927-37. PubMed ID: 24617852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Insights into the Translesion Synthesis of Benzyl-Guanine from Molecular Dynamics Simulations: Structural Evidence of Mutagenic and Nonmutagenic Replication.
    Wilson KA; Wetmore SD
    Biochemistry; 2017 Apr; 56(13):1841-1853. PubMed ID: 28290677
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.