229 related articles for article (PubMed ID: 24695733)
1. Binding site and inhibitory mechanism of the mambalgin-2 pain-relieving peptide on acid-sensing ion channel 1a.
Salinas M; Besson T; Delettre Q; Diochot S; Boulakirba S; Douguet D; Lingueglia E
J Biol Chem; 2014 May; 289(19):13363-73. PubMed ID: 24695733
[TBL] [Abstract][Full Text] [Related]
2. Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a.
Salinas M; Kessler P; Douguet D; Sarraf D; Tonali N; Thai R; Servent D; Lingueglia E
Neuropharmacology; 2021 Mar; 185():108453. PubMed ID: 33450275
[TBL] [Abstract][Full Text] [Related]
3. Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
Mourier G; Salinas M; Kessler P; Stura EA; Leblanc M; Tepshi L; Besson T; Diochot S; Baron A; Douguet D; Lingueglia E; Servent D
J Biol Chem; 2016 Feb; 291(6):2616-29. PubMed ID: 26680001
[TBL] [Abstract][Full Text] [Related]
4. Revealing molecular determinants governing mambalgin-3 pharmacology at acid-sensing ion channel 1 variants.
Cristofori-Armstrong B; Budusan E; Smith JJ; Reynaud S; Voll K; Chassagnon IR; Durek T; Rash LD
Cell Mol Life Sci; 2024 Jun; 81(1):266. PubMed ID: 38880807
[TBL] [Abstract][Full Text] [Related]
5. Cryo-EM structure of the ASIC1a-mambalgin-1 complex reveals that the peptide toxin mambalgin-1 inhibits acid-sensing ion channels through an unusual allosteric effect.
Sun D; Yu Y; Xue X; Pan M; Wen M; Li S; Qu Q; Li X; Zhang L; Li X; Liu L; Yang M; Tian C
Cell Discov; 2018; 4():27. PubMed ID: 29872539
[TBL] [Abstract][Full Text] [Related]
6. Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.
Schroeder CI; Rash LD; Vila-Farrés X; Rosengren KJ; Mobli M; King GF; Alewood PF; Craik DJ; Durek T
Angew Chem Int Ed Engl; 2014 Jan; 53(4):1017-20. PubMed ID: 24323786
[TBL] [Abstract][Full Text] [Related]
7. Black mamba venom peptides target acid-sensing ion channels to abolish pain.
Diochot S; Baron A; Salinas M; Douguet D; Scarzello S; Dabert-Gay AS; Debayle D; Friend V; Alloui A; Lazdunski M; Lingueglia E
Nature; 2012 Oct; 490(7421):552-5. PubMed ID: 23034652
[TBL] [Abstract][Full Text] [Related]
8. Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: Implications as an analgesic lead.
Cristofori-Armstrong B; Budusan E; Rash LD
Proc Natl Acad Sci U S A; 2021 Feb; 118(8):. PubMed ID: 33602819
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ).
Besson T; Lingueglia E; Salinas M
Neuropharmacology; 2017 Oct; 125():429-440. PubMed ID: 28802647
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of Action of the Peptide Toxins Targeting Human and Rodent Acid-Sensing Ion Channels and Relevance to Their In Vivo Analgesic Effects.
Verkest C; Salinas M; Diochot S; Deval E; Lingueglia E; Baron A
Toxins (Basel); 2022 Oct; 14(10):. PubMed ID: 36287977
[TBL] [Abstract][Full Text] [Related]
11. Mambalgins, the Venom-origin Peptides as a Potentially Novel Group of Analgesics: Mini Review.
Brzezicki MA; Zakowicz PT
CNS Neurol Disord Drug Targets; 2018; 17(2):87-97. PubMed ID: 29268691
[TBL] [Abstract][Full Text] [Related]
12. Mutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides.
Bargeton B; Iwaszkiewicz J; Bonifacio G; Roy S; Zoete V; Kellenberger S
Sci Rep; 2019 Feb; 9(1):2599. PubMed ID: 30796301
[TBL] [Abstract][Full Text] [Related]
13. Molecular Basis for Mambalgin-2 Interaction with Heterotrimeric α-ENaC/ASIC1a/γ-ENaC Channels in Cancer Cells.
Lyukmanova EN; Zaigraev MM; Kulbatskii DS; Isaev AB; Kukushkin ID; Bychkov ML; Shulepko MA; Chugunov AO; Kirpichnikov MP
Toxins (Basel); 2023 Oct; 15(10):. PubMed ID: 37888643
[TBL] [Abstract][Full Text] [Related]
14. Site-specific fluorescence spectrum detection and characterization of hASIC1a channels upon toxin mambalgin-1 binding in live mammalian cells.
Wen M; Guo X; Sun P; Xiao L; Li J; Xiong Y; Bao J; Xue T; Zhang L; Tian C
Chem Commun (Camb); 2015 May; 51(38):8153-6. PubMed ID: 25873388
[TBL] [Abstract][Full Text] [Related]
15. The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: Importance of interactions at the channel subunit interface and potential for engineering selective analogues.
Cristofori-Armstrong B; Saez NJ; Chassagnon IR; King GF; Rash LD
Biochem Pharmacol; 2019 May; 163():381-390. PubMed ID: 30849303
[TBL] [Abstract][Full Text] [Related]
16. Total synthesis of mambalgin-1/2/3 by two-segment hydrazide-based native chemical ligation.
Lan H; Wu K; Zheng Y; Pan M; Huang YC; Gao S; Zheng QY; Zheng JS; Li YM; Xiao B; Liu L
J Pept Sci; 2016 May; 22(5):320-6. PubMed ID: 26991634
[TBL] [Abstract][Full Text] [Related]
17. Conformational dynamics and role of the acidic pocket in ASIC pH-dependent gating.
Vullo S; Bonifacio G; Roy S; Johner N; Bernèche S; Kellenberger S
Proc Natl Acad Sci U S A; 2017 Apr; 114(14):3768-3773. PubMed ID: 28320963
[TBL] [Abstract][Full Text] [Related]
18. Analgesic effects of mambalgin peptide inhibitors of acid-sensing ion channels in inflammatory and neuropathic pain.
Diochot S; Alloui A; Rodrigues P; Dauvois M; Friend V; Aissouni Y; Eschalier A; Lingueglia E; Baron A
Pain; 2016 Mar; 157(3):552-559. PubMed ID: 26492527
[TBL] [Abstract][Full Text] [Related]
19. Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
Sun D; Liu S; Li S; Zhang M; Yang F; Wen M; Shi P; Wang T; Pan M; Chang S; Zhang X; Zhang L; Tian C; Liu L
Elife; 2020 Sep; 9():. PubMed ID: 32915133
[TBL] [Abstract][Full Text] [Related]
20. The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization.
Krauson AJ; Carattino MD
J Biol Chem; 2016 May; 291(21):11407-19. PubMed ID: 27015804
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
